{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T22:04:19Z","timestamp":1790114659101,"version":"4.0.1"},"reference-count":21,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2006,7,14]],"date-time":"2006-07-14T00:00:00Z","timestamp":1152835200000},"content-version":"vor","delay-in-days":4942,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Environ and Mol Mutagen"],"published-print":{"date-parts":[[1993,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Cytotoxic and cell transforming activities of the pesticides cyanazine, diflubenzuron, dithianon, procymidone, and vinclozolin were investigated in vitro by utilizing the BALB\/c 3T3 cell transformation test performed in the presence or in the absence of S\u20109 mix as an exogenous bioactivation system for the chemicals. All the assayed pesticides were cytotoxic in the absence of S\u20109 mix, whereas only dithianon exerted cytotoxic effects in the presence of metabolic activation. All the chemicals tested did induce BALB\/c 3T3 cell transformation, to a various extent, in the absence of S\u20109 mix. Cell transforming ability of cyanazine and diflubenzuron was not detectable in the presence of S\u20109. \u00a9 1993 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/em.2850210111","type":"journal-article","created":{"date-parts":[[2007,2,21]],"date-time":"2007-02-21T18:47:30Z","timestamp":1172083650000},"page":"81-86","source":"Crossref","is-referenced-by-count":35,"title":["In vitro cytotoxic and cell transforming activities exerted by the pesticides cyanazine, dithianon, diflubenzuron, procymidone, and vinclozolin on BALB\/c 3T3 cells"],"prefix":"10.1002","volume":"21","author":[{"given":"Paolo","family":"Perocco","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annamaria","family":"Colacci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandro","family":"Grilli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006,7,14]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1139\/g72-018"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0165-1161(75)90046-1"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0065-230X(08)60222-5"},{"key":"e_1_2_1_5_1","first-page":"267","volume-title":"Long\u2010term and Short\u2010term Assays for Carcinogens: a Critical Appraisal","author":"Barrett JC","year":"1986"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1114343"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-68511-8_64"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1349-7006.1990.tb02646.x"},{"key":"e_1_2_1_9_1","volume-title":"Registration Standard on February 2, 1985\u201d","author":"Environmental Protection Agency (EPA)","year":"1985"},{"key":"e_1_2_1_10_1","first-page":"1","volume-title":"Tox. 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