{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T05:08:46Z","timestamp":1791090526024,"version":"4.1.0"},"reference-count":20,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2006,7,14]],"date-time":"2006-07-14T00:00:00Z","timestamp":1152835200000},"content-version":"vor","delay-in-days":4577,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Environ and Mol Mutagen"],"published-print":{"date-parts":[[1994,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Fifty chemicals were tested for mutagenic activity in post\u2010meiotic and meiotic germ cells of male Drosophila melanogaster using the sex\u2010linked recessive lethal (SLRL) assay. As in the previous studies in this series, feeding was chosen as the first route of administration. If the compound failed to induce mutations by this route, injection exposure was used. One gaseous chemical (1,3\u2010butadiene) was tested only by inhalation. Those chemicals that were mutagenic in the sex\u2010linked recessive lethal assay were further tested for the ability to induce reciprocal translocations. Eleven of the 50 chemicals tested were mutagenic in the SLRL assay. These included bis(2\u2010chloroethyl) ether, 1,4\u2010butanediol diglycidyl ether, 1\u2010chloro\u20102\u2010propanol, dimethyl methylphosphonate, dimethyl morpholinophosphoramidate, dimethyloldihydroxy\u2010ethylene urea, 2,2\u2010dimethyl vinyl chloride, hexamethylphosphoramide, isatin\u20105\u2010sulfonic acid (Na salt), isopropyl glycidyl ether, and urethane. Five of these, including 1,4\u2010butanediol diglycidyl ether, 2,2\u2010dimethyl vinyl chloride, hexamethylphosphoramide, isopropyl glycidyl ether, and urethane, also induced reciprocal translocations. \u00a9 1994 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/em.2850230109","type":"journal-article","created":{"date-parts":[[2007,2,21]],"date-time":"2007-02-21T19:02:56Z","timestamp":1172084576000},"page":"51-63","source":"Crossref","is-referenced-by-count":51,"title":["Chemical mutagenesis testing in <i>Drosophila<\/i>. IX. Results of 50 coded compounds tested for the national toxicology program"],"prefix":"10.1002","volume":"23","author":[{"given":"P.","family":"Foureman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. 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