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The present report summarizes results which indicate that phototherapy is endowed with DNA\u2010modifying properties and has therefore the potential for inducing genetic and carcinogenic effects. These disconcerting findings concerning the long\u2010term hazardous consequences of an accepted therapeutic procedure require that the unique physiologic and pharmacologic characteristics of the newborn populations be recognized when assessing the risks and benefits of phototherapy.<\/jats:p>","DOI":"10.1002\/em.2860010404","type":"journal-article","created":{"date-parts":[[2007,2,20]],"date-time":"2007-02-20T21:38:53Z","timestamp":1172007533000},"page":"321-336","source":"Crossref","is-referenced-by-count":35,"title":["Phototherapy for neonatal hyperbilirubinemia\u2014a potential environmental health hazard to newborn infants: A review"],"prefix":"10.1002","volume":"1","author":[{"given":"William T.","family":"Speck","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Herbert S.","family":"Rosenkranz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,7,14]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(58)91849-X"},{"key":"e_1_2_1_3_2","first-page":"316","article-title":"Transmission of light through living tissue","volume":"7","author":"Sisson TRC","year":"1973","journal-title":"Pediatr Res"},{"key":"e_1_2_1_4_2","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1542\/peds.41.6.1047","article-title":"Prevention of hyperbilirubinemia of prematurity by phototherapy","volume":"41","author":"Lucy J","year":"1968","journal-title":"Pediatrics"},{"key":"e_1_2_1_5_2","first-page":"473","article-title":"Phototherapy and hyperbilirubinemia of the premature","volume":"219","author":"Hodgman JE","year":"1970","journal-title":"Am J Dis Child"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(71)80182-8"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(69)80475-0"},{"key":"e_1_2_1_8_2","first-page":"1191","article-title":"Riboflavin under the lights","volume":"1","year":"1978","journal-title":"Lancet"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(74)80575-5"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(78)90713-8"},{"key":"e_1_2_1_11_2","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1542\/peds.2.5.520","article-title":"Replacement transfusion as a treatment for erythroblastosis fetalis","volume":"2","author":"Diamond LK","year":"1948","journal-title":"Pediatrics"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0031-3955(16)31299-8"},{"key":"e_1_2_1_13_2","first-page":"294","article-title":"The photodecomposition of bilirubin and other bile pigments","volume":"288","author":"Gray CH","year":"1972","journal-title":"J Chem Soc Perkin I"},{"key":"e_1_2_1_14_2","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/S0016-5085(70)80087-7","article-title":"Photodecomposition of bilirubin and biliverdin in vitro","volume":"58","author":"Ostrow JD","year":"1970","journal-title":"Gastroenterology"},{"key":"e_1_2_1_15_2","first-page":"205","article-title":"Photodecomposition products of bilirubin. 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