{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T17:18:32Z","timestamp":1791307112882,"version":"4.3.1"},"reference-count":24,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2006,7,14]],"date-time":"2006-07-14T00:00:00Z","timestamp":1152835200000},"content-version":"vor","delay-in-days":7499,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Environ. mutagen"],"published-print":{"date-parts":[[1986,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The induction of several SOS genes of <jats:italic>Escherichia coli<\/jats:italic> such as <jats:italic>recA, umuC<\/jats:italic>, and <jats:italic>sfiA<\/jats:italic> by hexavalent (K<jats:sub>2<\/jats:sub>Cr<jats:sub>2<\/jats:sub>O<jats:sub>7<\/jats:sub>, K<jats:sub>2<\/jats:sub>CrO<jats:sub>4<\/jats:sub>, and CrO<jats:sub>3<\/jats:sub>) and trivalent (CrCl<jats:sub>3<\/jats:sub>, Cr(NO<jats:sub>3<\/jats:sub>)<jats:sub>3<\/jats:sub>, and (CH<jats:sub>3<\/jats:sub>COO)<jats:sub>3<\/jats:sub>Cr) compounds of chromium was studied. Induction was measured as \u03b2\u2010galactosidase activity, using <jats:italic>lacZ<\/jats:italic> gene fusions under the control region of different SOS genes. The hexavalent chromium forms induced the genes responsible for massive synthesis of RecA protein, error\u2010prone repair, and inhibition of cell division. On the other hand, the trivalent chromium compounds were unable to induce any of the SOS genes tested. Individual assay of hexavalent chromium compounds showed that K<jats:sub>2<\/jats:sub>Cr<jats:sub>2<\/jats:sub>O<jats:sub>7<\/jats:sub> was a stronger inducing agent of those three SOS genes tested than K<jats:sub>2<\/jats:sub>CrO<jats:sub>4<\/jats:sub>, which, in turn, was stronger than CrO<jats:sub>3<\/jats:sub>. All this data led to the conclusion that hexavalent chromium compounds, but not trivalent, are proficient agents of induction of the SOS system and can produce indirect mutagenesis in <jats:italic>Escherichia coli<\/jats:italic>.<\/jats:p>","DOI":"10.1002\/em.2860080408","type":"journal-article","created":{"date-parts":[[2007,2,20]],"date-time":"2007-02-20T22:51:05Z","timestamp":1172011865000},"page":"571-577","source":"Crossref","is-referenced-by-count":48,"title":["Induction of SOS genes of <i>Escherichia coli<\/i> by chromium compounds"],"prefix":"10.1002","volume":"8","author":[{"given":"Montserrat","family":"Llagostera","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salvador","family":"Garrido","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ricardo","family":"Guerrero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jordi","family":"Barb\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006,7,14]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"2079","article-title":"Discriminated induction of SOS functions in Escherichia coli by alkylating agents","volume":"129","author":"Barb\u00e9 J","year":"1983","journal-title":"J Gen Microbiol"},{"key":"e_1_2_1_3_1","doi-asserted-by":"crossref","unstructured":"Barb\u00e9J GibertI GuerreroR(1985): 5\u2010Azacytidine: survival and induction of SOS system in Escherichia coli K\u201012.Mutat Res(in press).","DOI":"10.1016\/0167-8817(86)90035-0"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0165-1218(83)90128-3"},{"key":"e_1_2_1_5_1","first-page":"147","article-title":"Genetic effects of potassium dichromate in Schizosaccharomyces pombe.","volume":"38","author":"Bonatti S","year":"1976","journal-title":"Mutat Res"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00334135"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00330785"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00405200"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/em.2860060307"},{"key":"e_1_2_1_10_1","first-page":"72","volume-title":"Mutagenicity, carcinogenicity and teratogenicity of industrial pollutants","author":"Leonard 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