{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T12:51:45Z","timestamp":1791982305806,"version":"4.4.0"},"reference-count":59,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2013,12,16]],"date-time":"2013-12-16T00:00:00Z","timestamp":1387152000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2013,12,16]],"date-time":"2013-12-16T00:00:00Z","timestamp":1387152000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"name":"Max Planck Society","award":["SFB670"],"award-info":[{"award-number":["SFB670"]}]},{"name":"MEXT of Japan","award":["20380027"],"award-info":[{"award-number":["20380027"]}]},{"name":"International Max Planck Research School Program"},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"crossref","award":["10J03196"],"award-info":[{"award-number":["10J03196"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["EMBO J"],"published-print":{"date-parts":[[2014,1,2]]},"DOI":"10.1002\/embj.201284303","type":"journal-article","created":{"date-parts":[[2013,12,16]],"date-time":"2013-12-16T13:32:37Z","timestamp":1387200757000},"page":"62-75","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":142,"title":["The Arabidopsis PEPR pathway couples local and systemic plant immunity"],"prefix":"10.1038","volume":"33","author":[{"given":"Annegret","family":"Ross","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kohji","family":"Yamada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kei","family":"Hiruma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Misuzu","family":"Yamashita\u2010Yamada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xunli","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshitaka","family":"Takano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenichi","family":"Tsuda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yusuke","family":"Saijo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2013,12,16]]},"reference":[{"key":"BFEMBJ201284303_CR1","doi-asserted-by":"crossref","first-page":"2148","DOI":"10.1126\/science.284.5423.2148","volume":"284","author":"JM Alonso","year":"1999","unstructured":"Alonso JM, Hirayama T, Roman G, Nourizadeh S, Ecker JR (1999) EIN2, a bifunctional transducer of ethylene and stress responses in Arabidopsis. Science 284: 2148\u20132152","journal-title":"Science"},{"key":"BFEMBJ201284303_CR2","doi-asserted-by":"crossref","first-page":"1038","DOI":"10.1105\/tpc.105.039982","volume":"18","author":"M Bartsch","year":"2006","unstructured":"Bartsch M, Gobbato E, Bednarek P, Debey S, Schultze JL, Bautor J, Parker JE (2006) Salicylic acid\u2010independent ENHANCED DISEASE SUSCEPTIBILITY1 signaling in Arabidopsis immunity and cell death is regulated by the monooxygenase FMO1 and the Nudix hydrolase NUDT7. Plant Cell 18: 1038\u20131051","journal-title":"Plant Cell"},{"key":"BFEMBJ201284303_CR3","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1104\/pp.104.057794","volume":"138","author":"P Bednarek","year":"2005","unstructured":"Bednarek P, Schneider B, Svatos A, Oldham NJ, Hahlbrock K (2005) Structural complexity, differential response to infection, and tissue specificity of indolic and phenylpropanoid secondary metabolism in Arabidopsis roots. Plant Physiol 138: 1058\u20131070","journal-title":"Plant Physiol"},{"key":"BFEMBJ201284303_CR4","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1146\/annurev.arplant.57.032905.105346","volume":"60","author":"T Boller","year":"2009","unstructured":"Boller T, Felix G (2009) A renaissance of elicitors: perception of microbe\u2010associated molecular patterns and danger signals by pattern\u2010recognition receptors. Annu Rev Plant Biol 60: 379\u2013406","journal-title":"Annu Rev Plant Biol"},{"key":"BFEMBJ201284303_CR5","doi-asserted-by":"crossref","first-page":"14502","DOI":"10.1073\/pnas.1003347107","volume":"107","author":"F Boutrot","year":"2010","unstructured":"Boutrot F, Segonzac C, Chang KN, Qiao H, Ecker JR, Zipfel C, Rathjen JP (2010) Direct transcriptional control of the Arabidopsis immune receptor FLS2 by the ethylene\u2010dependent transcription factors EIN3 and EIL1. Proc Natl Acad Sci USA 107: 14502\u201314507","journal-title":"Proc Natl Acad Sci USA"},{"key":"BFEMBJ201284303_CR6","doi-asserted-by":"crossref","first-page":"e11342","DOI":"10.1371\/journal.pone.0011342","volume":"5","author":"A Christensen","year":"2010","unstructured":"Christensen A, Svensson K, Thelin L, Zhang WJ, Tintor N, Prins D, Funke N, Michalak M, Schulze\u2010Lefert P, Saijo Y, Sommarin M, Widell S, Persson S (2010) Higher plant calreticulins have acquired specialized functions in Arabidopsis. PLoS One 5: e11342","journal-title":"PLoS One"},{"key":"BFEMBJ201284303_CR7","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1104\/pp.105.063743","volume":"139","author":"T Czechowski","year":"2005","unstructured":"Czechowski T, Stitt M, Altmann T, Udvardi MK, Scheible WR (2005) Genome\u2010wide identification and testing of superior reference genes for transcript normalization in Arabidopsis. Plant Physiol 139: 5\u201317","journal-title":"Plant Physiol"},{"key":"BFEMBJ201284303_CR8","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1016\/j.tplants.2012.05.011","volume":"17","author":"DA Dempsey","year":"2012","unstructured":"Dempsey DA, Klessig DF (2012) SOS \u2013 too many signals for systemic acquired resistance? Trends Plant Sci 17: 538\u2013545","journal-title":"Trends Plant Sci"},{"key":"BFEMBJ201284303_CR9","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1146\/annurev.phyto.42.040803.140421","volume":"42","author":"WE Durrant","year":"2004","unstructured":"Durrant WE, Dong X (2004) Systemic acquired resistance. Annu Rev Phytopathol 42: 185\u2013209","journal-title":"Annu Rev Phytopathol"},{"key":"BFEMBJ201284303_CR10","doi-asserted-by":"crossref","first-page":"2023","DOI":"10.1104\/pp.113.216077","volume":"161","author":"P Flury","year":"2013","unstructured":"Flury P, Klauser D, Schulze B, Boller T, Bartels S (2013) The anticipation of danger: microbe\u2010associated molecular pattern perception enhances AtPep\u2010triggered oxidative burst. Plant Physiol 161: 2023\u20132035","journal-title":"Plant Physiol"},{"key":"BFEMBJ201284303_CR11","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1111\/j.1600-065X.2011.01037.x","volume":"243","author":"MF Fontana","year":"2011","unstructured":"Fontana MF, Vance RE (2011) Two signal models in innate immunity. Immunol Rev 243: 26\u201339","journal-title":"Immunol Rev"},{"key":"BFEMBJ201284303_CR12","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1126\/science.7638602","volume":"269","author":"MR Grant","year":"1995","unstructured":"Grant MR, Godiard L, Straube E, Ashfield T, Lewald J, Sattler A, Innes RW, Dangl JL (1995) Structure of the Arabidopsis RPM1 gene enabling dual specificity disease resistance. Science 269: 843\u2013846","journal-title":"Science"},{"key":"BFEMBJ201284303_CR13","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1111\/j.1365-313X.2011.04651.x","volume":"67","author":"K Hiruma","year":"2011","unstructured":"Hiruma K, Nishiuchi T, Kato T, Bednarek P, Okuno T, Schulze\u2010Lefert P, Takano Y (2011) Arabidopsis ENHANCED DISEASE RESISTANCE 1 is required for pathogen\u2010induced expression of plant defensins in nonhost resistance, and acts through interference of MYC2\u2010mediated repressor function. Plant J 67: 980\u2013992","journal-title":"Plant J"},{"key":"BFEMBJ201284303_CR14","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.1104\/pp.110.166710","volume":"155","author":"A Huffaker","year":"2011","unstructured":"Huffaker A, Dafoe NJ, Schmelz EA (2011) ZmPep1, an ortholog of Arabidopsis elicitor peptide 1, regulates maize innate immunity and enhances disease resistance. Plant Physiol 155: 1325\u20131338","journal-title":"Plant Physiol"},{"key":"BFEMBJ201284303_CR15","doi-asserted-by":"crossref","first-page":"10098","DOI":"10.1073\/pnas.0603727103","volume":"103","author":"A Huffaker","year":"2006","unstructured":"Huffaker A, Pearce G, Ryan CA (2006) An endogenous peptide signal in Arabidopsis activates components of the innate immune response. Proc Natl Acad Sci USA 103: 10098\u201310103","journal-title":"Proc Natl Acad Sci USA"},{"key":"BFEMBJ201284303_CR16","doi-asserted-by":"crossref","first-page":"5707","DOI":"10.1073\/pnas.1214668110","volume":"110","author":"A Huffaker","year":"2013","unstructured":"Huffaker A, Pearce G, Veyrat N, Erb M, Turlings TC, Sartor R, Shen Z, Briggs SP, Vaughan MM, Alborn HT, Teal PE, Schmelz EA (2013) Plant elicitor peptides are conserved signals regulating direct and indirect antiherbivore defense. Proc Natl Acad Sci USA 110: 5707\u20135712","journal-title":"Proc Natl Acad Sci USA"},{"key":"BFEMBJ201284303_CR17","doi-asserted-by":"crossref","first-page":"10732","DOI":"10.1073\/pnas.0703343104","volume":"104","author":"A Huffaker","year":"2007","unstructured":"Huffaker A, Ryan CA (2007) Endogenous peptide defense signals in Arabidopsis differentially amplify signaling for the innate immune response. Proc Natl Acad Sci USA 104: 10732\u201310736","journal-title":"Proc Natl Acad Sci USA"},{"key":"BFEMBJ201284303_CR18","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1094\/MPMI-22-2-0143","volume":"22","author":"A Huser","year":"2009","unstructured":"Huser A, Takahara H, Schmalenbach W, O'Connell R (2009) Discovery of pathogenicity genes in the crucifer anthracnose fungus Colletotrichum higginsianum, using random insertional mutagenesis. Mol Plant Microbe Interact 22: 143\u2013156","journal-title":"Mol Plant Microbe Interact"},{"key":"BFEMBJ201284303_CR19","doi-asserted-by":"crossref","first-page":"13583","DOI":"10.1073\/pnas.96.23.13583","volume":"96","author":"D Jirage","year":"1999","unstructured":"Jirage D, Tootle TL, Reuber TL, Frost LN, Feys BJ, Parker JE, Ausubel FM, Glazebrook J (1999) Arabidopsis thaliana PAD4 encodes a lipase\u2010like gene that is important for salicylic acid signaling. Proc Natl Acad Sci USA 96: 13583\u201313588","journal-title":"Proc Natl Acad Sci USA"},{"key":"BFEMBJ201284303_CR20","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1016\/j.immuni.2011.05.006","volume":"34","author":"T Kawai","year":"2011","unstructured":"Kawai T, Akira S (2011) Toll\u2010like receptors and their crosstalk with other innate receptors in infection and immunity. Immunity 34: 637\u2013650","journal-title":"Immunity"},{"key":"BFEMBJ201284303_CR21","doi-asserted-by":"crossref","first-page":"e25346","DOI":"10.4161\/psb.25346","volume":"8","author":"D Klauser","year":"2013","unstructured":"Klauser D, Flury P, Boller T, Bartels S (2013) Several MAMPs, including chitin fragments, enhance AtPep\u2010triggered oxidative burst independently of wounding. Plant Signal Behav 8: e25346","journal-title":"Plant Signal Behav"},{"key":"BFEMBJ201284303_CR22","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1111\/j.1365-313X.2006.02813.x","volume":"47","author":"M Koch","year":"2006","unstructured":"Koch M, Vorwerk S, Masur C, Sharifi\u2010Sirchi G, Olivieri N, Schlaich NL (2006) A role for a flavin\u2010containing mono\u2010oxygenase in resistance against microbial pathogens in Arabidopsis. Plant J 47: 629\u2013639","journal-title":"Plant J"},{"key":"BFEMBJ201284303_CR23","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1094\/PHYTO.1998.88.7.692","volume":"88","author":"HI Lee","year":"1998","unstructured":"Lee HI, Raskin I (1998) Glucosylation of salicylic acid in Nicotiana tabacum cv. Xanthi\u2010nc. Phytopathology 88: 692\u2013697","journal-title":"Phytopathology"},{"key":"BFEMBJ201284303_CR24","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1094\/MPMI-23-2-0187","volume":"23","author":"A Leon\u2010Reyes","year":"2010","unstructured":"Leon\u2010Reyes A, Du Y, Koornneef A, Proietti S, Korbes AP, Memelink J, Pieterse CM, Ritsema T (2010) Ethylene signaling renders the jasmonate response of Arabidopsis insensitive to future suppression by salicylic Acid. Mol Plant Microbe Interact 23: 187\u2013197","journal-title":"Mol Plant Microbe Interact"},{"key":"BFEMBJ201284303_CR25","doi-asserted-by":"crossref","first-page":"1180","DOI":"10.1126\/science.1119409","volume":"310","author":"V Lipka","year":"2005","unstructured":"Lipka V, Dittgen J, Bednarek P, Bhat R, Wiermer M, Stein M, Landtag J, Brandt W, Rosahl S, Scheel D, Llorente F, Molina A, Parker J, Somerville S, Schulze\u2010Lefert P (2005) Pre\u2010 and postinvasion defenses both contribute to nonhost resistance in Arabidopsis. Science 310: 1180\u20131183","journal-title":"Science"},{"key":"BFEMBJ201284303_CR26","doi-asserted-by":"crossref","first-page":"6205","DOI":"10.1073\/pnas.1215543110","volume":"110","author":"Z Liu","year":"2013","unstructured":"Liu Z, Wu Y, Yang F, Zhang Y, Chen S, Xie Q, Tian X, Zhou JM (2013) BIK1 interacts with PEPRs to mediate ethylene\u2010induced immunity. Proc Natl Acad Sci USA 110: 6205\u20136210","journal-title":"Proc Natl Acad Sci USA"},{"key":"BFEMBJ201284303_CR27","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1111\/nph.12233","volume":"198","author":"E Logemann","year":"2013","unstructured":"Logemann E, Birkenbihl RP, Rawat V, Schneeberger K, Schmelzer E, Somssich IE (2013) Functional dissection of the PROPEP2 and PROPEP3 promoters reveals the importance of WRKY factors in mediating microbe\u2010associated molecular pattern\u2010induced expression. New Phytol 198: 1165\u20131177","journal-title":"New Phytol"},{"key":"BFEMBJ201284303_CR28","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1146\/annurev.phyto.44.070505.143425","volume":"44","author":"LC van Loon","year":"2006","unstructured":"van Loon LC, Rep M, Pieterse CM (2006) Significance of inducible defense\u2010related proteins in infected plants. Annu Rev Phytopathol 44: 135\u2013162","journal-title":"Annu Rev Phytopathol"},{"key":"BFEMBJ201284303_CR29","doi-asserted-by":"crossref","first-page":"22522","DOI":"10.1073\/pnas.0907711106","volume":"106","author":"X Lu","year":"2009","unstructured":"Lu X, Tintor N, Mentzel T, Kombrink E, Boller T, Robatzek S, Schulze\u2010Lefert P, Saijo Y (2009) Uncoupling of sustained MAMP receptor signaling from early outputs in an Arabidopsis endoplasmic reticulum glucosidase II allele. Proc Natl Acad Sci USA 106: 22522\u201322527","journal-title":"Proc Natl Acad Sci USA"},{"key":"BFEMBJ201284303_CR30","doi-asserted-by":"crossref","first-page":"19852","DOI":"10.1073\/pnas.1205448109","volume":"109","author":"Y Ma","year":"2012","unstructured":"Ma Y, Walker RK, Zhao Y, Berkowitz GA (2012) Linking ligand perception by PEPR pattern recognition receptors to cytosolic Ca2+ elevation and downstream immune signaling in plants. Proc Natl Acad Sci USA 109: 19852\u201319857","journal-title":"Proc Natl Acad Sci USA"},{"key":"BFEMBJ201284303_CR31","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1104\/pp.110.154567","volume":"154","author":"S Mersmann","year":"2010","unstructured":"Mersmann S, Bourdais G, Rietz S, Robatzek S (2010) Ethylene signaling regulates accumulation of the FLS2 receptor and is required for the oxidative burst contributing to plant immunity. Plant Physiol 154: 391\u2013400","journal-title":"Plant Physiol"},{"key":"BFEMBJ201284303_CR32","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1111\/j.1365-313X.2007.03067.x","volume":"50","author":"TE Mishina","year":"2007","unstructured":"Mishina TE, Zeier J (2007) Pathogen\u2010associated molecular pattern recognition rather than development of tissue necrosis contributes to bacterial induction of systemic acquired resistance in Arabidopsis. Plant J 50: 500\u2013513","journal-title":"Plant J"},{"key":"BFEMBJ201284303_CR33","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1111\/j.1365-313X.2009.03949.x","volume":"60","author":"M Narusaka","year":"2009","unstructured":"Narusaka M, Shirasu K, Noutoshi Y, Kubo Y, Shiraishi T, Iwabuchi M, Narusaka Y (2009) RRS1 and RPS4 provide a dual Resistance\u2010gene system against fungal and bacterial pathogens. Plant J 60: 218\u2013226","journal-title":"Plant J"},{"key":"BFEMBJ201284303_CR34","doi-asserted-by":"crossref","first-page":"5123","DOI":"10.1105\/tpc.112.103564","volume":"24","author":"H Navarova","year":"2012","unstructured":"Navarova H, Bernsdorff F, Doring AC, Zeier J (2012) Pipecolic acid, an endogenous mediator of defense amplification and priming, is a critical regulator of inducible plant immunity. Plant Cell 24: 5123\u20135141","journal-title":"Plant Cell"},{"key":"BFEMBJ201284303_CR35","doi-asserted-by":"crossref","first-page":"3428","DOI":"10.1038\/emboj.2009.262","volume":"28","author":"V Nekrasov","year":"2009","unstructured":"Nekrasov V, Li J, Batoux M, Roux M, Chu ZH, Lacombe S, Rougon A, Bittel P, Kiss\u2010Papp M, Chinchilla D, van Esse HP, Jorda L, Schwessinger B, Nicaise V, Thomma BP, Molina A, Jones JD, Zipfel C (2009) Control of the pattern\u2010recognition receptor EFR by an ER protein complex in plant immunity. EMBO J 28: 3428\u20133438","journal-title":"EMBO J"},{"key":"BFEMBJ201284303_CR36","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1046\/j.1365-313X.2002.01328.x","volume":"31","author":"JH Park","year":"2002","unstructured":"Park JH, Halitschke R, Kim HB, Baldwin IT, Feldmann KA, Feyereisen R (2002) A knock\u2010out mutation in allene oxide synthase results in male sterility and defective wound signal transduction in Arabidopsis due to a block in jasmonic acid biosynthesis. Plant J 31: 1\u201312","journal-title":"Plant J"},{"key":"BFEMBJ201284303_CR37","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1146\/annurev-cellbio-092910-154055","volume":"28","author":"CM Pieterse","year":"2012","unstructured":"Pieterse CM, Van der Does D, Zamioudis C, Leon\u2010Reyes A, Van Wees SC (2012) Hormonal modulation of plant immunity. Annu Rev Cell Dev Biol 28: 489\u2013521","journal-title":"Annu Rev Cell Dev Biol"},{"key":"BFEMBJ201284303_CR38","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1146\/annurev-phyto-073009-114447","volume":"49","author":"A Robert\u2010Seilaniantz","year":"2011","unstructured":"Robert\u2010Seilaniantz A, Grant M, Jones JD (2011) Hormone crosstalk in plant disease and defense: more than just jasmonate\u2010salicylate antagonism. Annu Rev Phytopathol 49: 317\u2013343","journal-title":"Annu Rev Phytopathol"},{"key":"BFEMBJ201284303_CR39","doi-asserted-by":"crossref","first-page":"1902","DOI":"10.1111\/j.1462-5822.2007.00991.x","volume":"9","author":"CA Ryan","year":"2007","unstructured":"Ryan CA, Huffaker A, Yamaguchi Y (2007) New insights into innate immunity in Arabidopsis. Cell Microbiol 9: 1902\u20131908","journal-title":"Cell Microbiol"},{"key":"BFEMBJ201284303_CR40","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1111\/j.1462-5822.2010.01472.x","volume":"12","author":"Y Saijo","year":"2010","unstructured":"Saijo Y (2010) ER quality control of immune receptors and regulators in plants. Cell Microbiol 12: 716\u2013724","journal-title":"Cell Microbiol"},{"key":"BFEMBJ201284303_CR41","doi-asserted-by":"crossref","first-page":"3439","DOI":"10.1038\/emboj.2009.263","volume":"28","author":"Y Saijo","year":"2009","unstructured":"Saijo Y, Tintor N, Lu X, Rauf P, Pajerowska\u2010Mukhtar K, Haweker H, Dong X, Robatzek S, Schulze\u2010Lefert P (2009) Receptor quality control in the endoplasmic reticulum for plant innate immunity. EMBO J 28: 3439\u20133449","journal-title":"EMBO J"},{"key":"BFEMBJ201284303_CR42","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/j.pbi.2005.05.008","volume":"8","author":"AL Schilmiller","year":"2005","unstructured":"Schilmiller AL, Howe GA (2005) Systemic signaling in the wound response. Curr Opin Plant Biol 8: 369\u2013377","journal-title":"Curr Opin Plant Biol"},{"key":"BFEMBJ201284303_CR43","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.mib.2010.12.005","volume":"14","author":"C Segonzac","year":"2011","unstructured":"Segonzac C, Zipfel C (2011) Activation of plant pattern\u2010recognition receptors by bacteria. Curr Opin Microbiol 14: 54\u201361","journal-title":"Curr Opin Microbiol"},{"key":"BFEMBJ201284303_CR44","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1104\/pp.111.183459","volume":"158","author":"M Serrano","year":"2012","unstructured":"Serrano M, Kanehara K, Torres M, Yamada K, Tintor N, Kombrink E, Schulze\u2010Lefert P, Saijo Y (2012) Repression of sucrose\/ultraviolet B light\u2010induced flavonoid accumulation in microbe\u2010associated molecular pattern\u2010triggered immunity in Arabidopsis. Plant Physiol 158: 408\u2013422","journal-title":"Plant Physiol"},{"key":"BFEMBJ201284303_CR45","doi-asserted-by":"crossref","first-page":"4293","DOI":"10.1038\/sj.emboj.7601854","volume":"26","author":"QH Shen","year":"2007","unstructured":"Shen QH, Schulze\u2010Lefert P (2007) Rumble in the nuclear jungle: compartmentalization, trafficking, and nuclear action of plant immune receptors. EMBO J 26: 4293\u20134301","journal-title":"EMBO J"},{"key":"BFEMBJ201284303_CR46","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1111\/j.1365-313X.2004.02200.x","volume":"40","author":"JT Song","year":"2004","unstructured":"Song JT, Lu H, McDowell JM, Greenberg JT (2004) A key role for ALD1 in activation of local and systemic defenses in Arabidopsis. Plant J 40: 200\u2013212","journal-title":"Plant J"},{"key":"BFEMBJ201284303_CR47","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1007\/s00425-002-0902-6","volume":"216","author":"BP Thomma","year":"2002","unstructured":"Thomma BP, Cammue BP, Thevissen K (2002) Plant defensins. Planta 216: 193\u2013202","journal-title":"Planta"},{"key":"BFEMBJ201284303_CR48","doi-asserted-by":"crossref","first-page":"6211","DOI":"10.1073\/pnas.1216780110","volume":"110","author":"N Tintor","year":"2013","unstructured":"Tintor N, Ross A, Kanehara K, Yamada K, Fan L, Kemmerling B, Nurnberger T, Tsuda K, Saijo Y (2013) Layered pattern receptor signaling via ethylene and endogenous elicitor peptides during Arabidopsis immunity to bacterial infection. Proc Natl Acad Sci USA 110: 6211\u20136216","journal-title":"Proc Natl Acad Sci USA"},{"key":"BFEMBJ201284303_CR49","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1073\/pnas.0605423104","volume":"104","author":"W Truman","year":"2007","unstructured":"Truman W, Bennett MH, Kubigsteltig I, Turnbull C, Grant M (2007) Arabidopsis systemic immunity uses conserved defense signaling pathways and is mediated by jasmonates. Proc Natl Acad Sci USA 104: 1075\u20131080","journal-title":"Proc Natl Acad Sci USA"},{"key":"BFEMBJ201284303_CR50","doi-asserted-by":"crossref","first-page":"e1000772","DOI":"10.1371\/journal.pgen.1000772","volume":"5","author":"K Tsuda","year":"2009","unstructured":"Tsuda K, Sato M, Stoddard T, Glazebrook J, Katagiri F (2009) Network properties of robust immunity in plants. PLoS Genet 5: e1000772","journal-title":"PLoS Genet"},{"key":"BFEMBJ201284303_CR51","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.1126\/science.1108791","volume":"308","author":"D Wang","year":"2005","unstructured":"Wang D, Weaver ND, Kesarwani M, Dong X (2005) Induction of protein secretory pathway is required for systemic acquired resistance. Science 308: 1036\u20131040","journal-title":"Science"},{"key":"BFEMBJ201284303_CR52","doi-asserted-by":"crossref","first-page":"8711","DOI":"10.1073\/pnas.130425197","volume":"97","author":"SC van Wees","year":"2000","unstructured":"van Wees SC, de Swart EA, van Pelt JA, van Loon LC, Pieterse CM (2000) Enhancement of induced disease resistance by simultaneous activation of salicylate\u2010 and jasmonate\u2010dependent defense pathways in Arabidopsis thaliana. Proc Natl Acad Sci USA 97: 8711\u20138716","journal-title":"Proc Natl Acad Sci USA"},{"key":"BFEMBJ201284303_CR53","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1038\/35107108","volume":"414","author":"MC Wildermuth","year":"2001","unstructured":"Wildermuth MC, Dewdney J, Wu G, Ausubel FM (2001) Isochorismate synthase is required to synthesize salicylic acid for plant defence. Nature 414: 562\u2013565","journal-title":"Nature"},{"key":"BFEMBJ201284303_CR54","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/j.pbi.2011.05.001","volume":"14","author":"Y Yamaguchi","year":"2011","unstructured":"Yamaguchi Y, Huffaker A (2011) Endogenous peptide elicitors in higher plants. Curr Opin Plant Biol 14: 351\u2013357","journal-title":"Curr Opin Plant Biol"},{"key":"BFEMBJ201284303_CR55","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1105\/tpc.109.068874","volume":"22","author":"Y Yamaguchi","year":"2010","unstructured":"Yamaguchi Y, Huffaker A, Bryan AC, Tax FE, Ryan CA (2010) PEPR2 is a second receptor for the Pep1 and Pep2 peptides and contributes to defense responses in Arabidopsis. Plant Cell 22: 508\u2013522","journal-title":"Plant Cell"},{"key":"BFEMBJ201284303_CR56","doi-asserted-by":"crossref","first-page":"10104","DOI":"10.1073\/pnas.0603729103","volume":"103","author":"Y Yamaguchi","year":"2006","unstructured":"Yamaguchi Y, Pearce G, Ryan CA (2006) The cell surface leucine\u2010rich repeat receptor for AtPep1, an endoaenous peptide elicitor in Arabidopsis, is functional in transgenic tobacco cells. Proc Natl Acad Sci USA 103: 10104\u201310109","journal-title":"Proc Natl Acad Sci USA"},{"key":"BFEMBJ201284303_CR57","doi-asserted-by":"crossref","first-page":"6399","DOI":"10.1128\/jb.178.21.6399-6402.1996","volume":"178","author":"J Yuan","year":"1996","unstructured":"Yuan J, He SY (1996) The Pseudomonas syringae Hrp regulation and secretion system controls the production and secretion of multiple extracellular proteins. J Bacteriol 178: 6399\u20136402","journal-title":"J Bacteriol"},{"key":"BFEMBJ201284303_CR58","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1016\/j.cell.2006.03.037","volume":"125","author":"C Zipfel","year":"2006","unstructured":"Zipfel C, Kunze G, Chinchilla D, Caniard A, Jones JD, Boller T, Felix G (2006) Perception of the bacterial PAMP EF\u2010Tu by the receptor EFR restricts Agrobacterium\u2010mediated transformation. Cell 125: 749\u2013760","journal-title":"Cell"},{"key":"BFEMBJ201284303_CR59","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1038\/nature02485","volume":"428","author":"C Zipfel","year":"2004","unstructured":"Zipfel C, Robatzek S, Navarro L, Oakeley EJ, Jones JD, Felix G, Boller T (2004) Bacterial disease resistance in Arabidopsis through flagellin perception. Nature 428: 764\u2013767","journal-title":"Nature"}],"container-title":["The EMBO Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fembj.201284303","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1002\/embj.201284303.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1002\/embj.201284303\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1002\/embj.201284303.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T19:16:24Z","timestamp":1779304584000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1002\/embj.201284303"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,12,16]]},"references-count":59,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,1,2]]}},"alternative-id":["BFEMBJ201284303"],"URL":"https:\/\/doi.org\/10.1002\/embj.201284303","relation":{},"ISSN":["0261-4189","1460-2075"],"issn-type":[{"value":"0261-4189","type":"print"},{"value":"1460-2075","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,12,16]]},"assertion":[{"value":"21 December 2012","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 October 2013","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"31 October 2013","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 December 2013","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare that they have no conflict of interest.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}