{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T14:59:47Z","timestamp":1747148387618,"version":"3.40.5"},"reference-count":18,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2023,7,4]],"date-time":"2023-07-04T00:00:00Z","timestamp":1688428800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Epileptic Disorders"],"published-print":{"date-parts":[[2023,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Epileptic nystagmus (EN) is an uncommon ictal clinical manifestation characterized by rapid, repetitive eyeballs movements. Few cases of EN have been reported and, in most cases, electro\u2010clinical correlation showed a focal EEG activity, mainly in the occipital and temporo\u2010occipital areas. Although EN occurs both in idiopathic and non\u2010idiopathic epilepsy, the most frequent cause appears to be inborn or acquired alteration of brain structures. We report of a 12\u2010year\u2010old girl with EN as ictal manifestation of self\u2010limited focal seizures. We described clinical manifestations, electroencephalographic features, treatment, and follow\u2010up, presenting the ictal video\u2010EEG phenomenon. Alongside, we reviewed the reported clinical features of the few pediatric cases (seven patients) with idiopathic epileptic nystagmus through a systematic literature review. Isolated Epileptic Nystagmus (IEN) is much rarer than EN, as it is more frequently associated with other types of seizures, and can be idiopathic, especially in children. Epilepsy prognosis is usually favorable with appropriate treatment, and ASM discontinuation seems to be successful after few years of treatment.<\/jats:p>","DOI":"10.1002\/epd2.20087","type":"journal-article","created":{"date-parts":[[2023,6,24]],"date-time":"2023-06-24T04:28:58Z","timestamp":1687580938000},"page":"549-555","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Epileptic nystagmus as clinical manifestation of self\u2010limited focal epilepsy: Rethinking etiology and prognostic value and literature review"],"prefix":"10.1002","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9365-8335","authenticated-orcid":false,"given":"Brunetti","family":"Sara","sequence":"first","affiliation":[{"name":"Unit of Child Neurology and Psychiatry ASST Spedali Civili of Brescia  Brescia Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cocco","family":"Isabella","sequence":"additional","affiliation":[{"name":"Department of Clinical and Experimental Sciences University of Brescia  Brescia Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Damioli","family":"Simona","sequence":"additional","affiliation":[{"name":"Department of Clinical and Experimental Sciences University of Brescia  Brescia Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Accorsi","family":"Patrizia","sequence":"additional","affiliation":[{"name":"Unit of Child Neurology and Psychiatry ASST Spedali Civili of Brescia  Brescia Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tassi","family":"Laura","sequence":"additional","affiliation":[{"name":"\u201cClaudio Munari\u201d Epilepsy Surgery Centre ASST Niguarda Hospital  Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giordano","family":"Lucio","sequence":"additional","affiliation":[{"name":"Unit of Child Neurology and Psychiatry ASST Spedali Civili of Brescia  Brescia Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,7,4]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-510X(97)00102-0"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yebeh.2008.07.015"},{"issue":"8","key":"e_1_2_6_4_1","first-page":"13500","article-title":"Two types of isolated epileptic nystagmus: case report","volume":"8","author":"Ma Y","year":"2015","journal-title":"Int J Clin Exp Med"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1157.1984.tb03470.x"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1157.1984.tb04150.x"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1684\/j.1950-6945.2001.tb00463.x"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1177\/155005940303400111"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2010.08.022"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.3342\/ceo.2013.6.4.259"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-006-0114-2"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.40.4.662"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1982.00510220051012"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1157.1989.tb05293.x"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1177\/155005940603700109"},{"issue":"7","key":"e_1_2_6_16_1","first-page":"273","article-title":"Nystagmus attacks in temporal lobe epilepsy","volume":"20","author":"Arend R","year":"1968","journal-title":"Psychiatr Neurol Med Psychol"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/115.6.1655"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-004-0463-7"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pediatrneurol.2020.06.001"}],"container-title":["Epileptic Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/epd2.20087","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,18]],"date-time":"2024-03-18T16:07:27Z","timestamp":1710778047000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/epd2.20087"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7,4]]},"references-count":18,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023,8]]}},"alternative-id":["10.1002\/epd2.20087"],"URL":"https:\/\/doi.org\/10.1002\/epd2.20087","archive":["Portico"],"relation":{},"ISSN":["1294-9361","1950-6945"],"issn-type":[{"type":"print","value":"1294-9361"},{"type":"electronic","value":"1950-6945"}],"subject":[],"published":{"date-parts":[[2023,7,4]]},"assertion":[{"value":"2023-01-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-05-23","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-07-04","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}