{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T05:53:39Z","timestamp":1792043619896,"version":"4.4.0"},"reference-count":23,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,3,18]],"date-time":"2024-03-18T00:00:00Z","timestamp":1710720000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Epileptic Disorders"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Photosensitivity is known to occur predominantly in children and adolescents and with a clear female predominance. Little is known on the prevalence of photosensitivity in older patients (50+) and its phenotypical appearance.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective observational study was performed investigating the prevalence of a photoparoxysmal EEG response (PPR) on at least one EEG during the period 2015\u20132021. Data were gathered from patients aged 50\u2009years and older by retrieving clinical and EEG characteristics from existing medical records. Data on photosensitivity\u2010related symptoms in daily life were gathered with telephone interviewing.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In 248 patients a PPR had been elicited, of whom 16 patients (6.5%) were 50\u2009years or older. In older patients, photosensitivity was a persistent feature of childhood\u2010onset epilepsy (<jats:italic>n<\/jats:italic>\u2009=\u20098), of adult\u2010onset epilepsy (<jats:italic>n<\/jats:italic>\u2009=\u20097), or an incidental finding (<jats:italic>n<\/jats:italic>\u2009=\u20091). In the 50+ group, 56% of photosensitive patients was female, whereas 72% in the total PPR\u2010group. In six of 16 older patients, eye closure sensitivity was observed; two of these patients reported self\u2010induction. Symptoms of photosensitivity in daily life were present in eight out of nine patients who consented in a telephone interview. For seven of these patients, wearing sunglasses was helpful.<\/jats:p><\/jats:sec><jats:sec><jats:title>Significance<\/jats:title><jats:p>Female preponderance for photosensitivity was not found in epilepsy patients of 50\u2009years and older. In 44% of the older photosensitive patients in this series, the PPR was a feature of adult\u2010onset epilepsy. Symptoms of photosensitivity in daily life in older patients with epilepsy seem comparable to those in younger patients, and thus worthwhile to diagnose and treat them equally.<\/jats:p><\/jats:sec>","DOI":"10.1002\/epd2.20209","type":"journal-article","created":{"date-parts":[[2024,3,18]],"date-time":"2024-03-18T15:14:37Z","timestamp":1710774877000},"page":"293-301","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Photosensitivity and self\u2010induction in patients aged 50 and older"],"prefix":"10.1002","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-0084-9829","authenticated-orcid":false,"given":"C. J. J.","family":"van Asch","sequence":"first","affiliation":[{"name":"Stichting Epilepsie Instellingen Nederland (SEIN)  Hoofddorp The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W. P. J.","family":"Spetgens","sequence":"additional","affiliation":[{"name":"Stichting Epilepsie Instellingen Nederland (SEIN)  Hoofddorp The Netherlands"},{"name":"University Medical Center Utrecht  Utrecht The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. D.","family":"Bourez\u2010Swart","sequence":"additional","affiliation":[{"name":"Stichting Epilepsie Instellingen Nederland (SEIN)  Hoofddorp The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. M.","family":"Meppelink","sequence":"additional","affiliation":[{"name":"Stichting Epilepsie Instellingen Nederland (SEIN)  Hoofddorp The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. L. P.","family":"Deckers","sequence":"additional","affiliation":[{"name":"Stichting Epilepsie Instellingen Nederland (SEIN)  Hoofddorp The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"van Blooijs","sequence":"additional","affiliation":[{"name":"Stichting Epilepsie Instellingen Nederland (SEIN)  Hoofddorp The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. G. A.","family":"Kasteleijn\u2010Nolst\u00a0Trenit\u00e9","sequence":"additional","affiliation":[{"name":"University Medical Center Utrecht  Utrecht The Netherlands"},{"name":"Sapienza University  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,3,18]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.seizure.2017.04.001"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.seizure.2015.11.005"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1157.1997.tb01235.x"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1684\/epd.2015.0765"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/155005948101200104"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1167.2011.03319.x"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eplepsyres.2020.106377"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/0013-4694(92)90027-F"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1000934"},{"key":"e_1_2_7_11_1","first-page":"3","article-title":"Photosensitivity in epilepsy: electrophysiological and clinical correlates","volume":"125","author":"Kasteleijn\u2010Nolst Trenit\u00e9 DG","year":"1989","journal-title":"Acta Neurol Scand Suppl"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.seizure.2021.06.014"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.50.11.1546"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/afj024"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/NRL.0000000000000175"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005053-195906000-00003"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.seizure.2010.12.013"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/epi4.12671"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2020.10.029"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0013-9580.2004.451008.x"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0013-4694(97)00146-6"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00417-012-2006-8"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/0013-4694(95)00118-I"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1167.2006.00463.x"}],"container-title":["Epileptic Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/epd2.20209","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,7]],"date-time":"2024-06-07T08:36:00Z","timestamp":1717749360000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/epd2.20209"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,18]]},"references-count":23,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2024,6]]}},"alternative-id":["10.1002\/epd2.20209"],"URL":"https:\/\/doi.org\/10.1002\/epd2.20209","archive":["Portico"],"relation":{},"ISSN":["1294-9361","1950-6945"],"issn-type":[{"value":"1294-9361","type":"print"},{"value":"1950-6945","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,3,18]]},"assertion":[{"value":"2023-11-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-02-07","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-03-18","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}