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Participants were interviewed to obtain demographic and medical history, and were subjected to neurologic examinations. Epilepsy cases at baseline were determined with either diagnosis by a neurologist or anti\u2010seizure medication prescriptions confirmed by medical records. Deaths were confirmed by the local mortality surveillance system.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Twenty\u2010six participants were determined to be people with epilepsy, indicating the prevalence rate of 7.40\/1000 (95% CI 4.84, 10.82). People with epilepsy had a significantly higher chance of comorbidity with chronic obstructive pulmonary disease (COPD) (OR\u2009=\u200915.89, 95% CI 1.88, 133.98), depression (OR\u2009=\u200914.22, 95% CI 5.99, 33.73), and dementia (OR\u2009=\u20094.65, 95% CI 1.28, 16.89) compared to people without epilepsy. The overall mortality rate was 27.74\/1000 person\u2010years (95%CI 12.21, 53.97) in people with epilepsy and 26.32 (95% CI 24.75, 27.97) in people without epilepsy. Women aged 60\u201369\u2009years exhibited a high mortality ratio of 5.84 (95% CI 1.58, 21.64) compared to those without epilepsy within the same age group. The top three causes of death in people with and without epilepsy were similar. COPD was significantly associated with increased mortality risk in people with epilepsy (HR\u2009=\u200922.68; 95% CI 1.30, 396.70), but not in those without epilepsy. People with epilepsy and COPD had a higher risk of mortality than those without epilepsy and COPD (HR\u2009=\u200912.58, 95% CI 1.76, 89.68).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Significance<\/jats:title>\n                    <jats:p>Our study presented an epidemiological profile of epilepsy in an older community cohort and suggested a potential burden of neuropsychiatric and respiratory comorbidities, which needs further validation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/epd2.70151","type":"journal-article","created":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T15:04:59Z","timestamp":1765638299000},"page":"359-368","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Prevalence, comorbidities, and mortality of epilepsy in an older Chinese population: The Shanghai Aging Study"],"prefix":"10.1002","volume":"28","author":[{"given":"Can","family":"Cui","sequence":"first","affiliation":[{"name":"Department of Neurology, Huashan Hospital Fudan University  Shanghai China"},{"name":"National Clinical Research Center for Aging and Medicine, Huashan Hospital Fudan University  Shanghai China"},{"name":"National Center for Neurological Disorders, Huashan Hospital Fudan University  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaowen","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Neurology, Huashan Hospital Fudan University  Shanghai China"},{"name":"National Clinical Research Center for Aging and Medicine, Huashan Hospital Fudan University  Shanghai China"},{"name":"National Center for Neurological Disorders, Huashan Hospital Fudan University  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianhong","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Neurology, Huashan Hospital Fudan University  Shanghai China"},{"name":"National Clinical Research Center for Aging and Medicine, Huashan Hospital Fudan University  Shanghai China"},{"name":"National Center for Neurological Disorders, Huashan Hospital Fudan University  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qianhua","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Neurology, Huashan Hospital Fudan University  Shanghai China"},{"name":"National Clinical Research Center for Aging and Medicine, Huashan Hospital Fudan University  Shanghai China"},{"name":"National Center for Neurological Disorders, Huashan Hospital Fudan University  Shanghai 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