{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T07:40:32Z","timestamp":1776325232527,"version":"3.50.1"},"reference-count":24,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T00:00:00Z","timestamp":1768176000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T00:00:00Z","timestamp":1768176000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Epileptic Disorders"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study aimed to evaluate the usefulness of intraoperative electrocorticography (iECoG) in providing a more accurate surgical strategy, thereby yielding seizure freedom following resective surgery in children with temporal lobe epilepsy (TLE).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The authors conducted a retrospective review of pediatric patients with drug\u2010resistant TLE due to various etiologies, within a relatively long follow\u2010up (range 8.5\u201311.5\u2009years). Patients were divided into two groups based on whether they were operated on using iECoG or not, which was employed in cases of uncertain delineation of the EZ or anticipated extended resection. The efficacy of surgical treatment was assessed using Engel's classification. Seizure\u2010freedom rate for each etiology was compared between groups using Fisher's exact test with a 95% confidence interval.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 81 patients were included in the study (mean age 11.8\u2009years, range 1\u201318\u2009years), of whom 63 (77.8%) achieved Engel I status after 10\u2009years. The main etiology was hippocampal sclerosis (34\/81, 41.9%), followed by tumors (25\/81, 30.8%) and focal cortical dysplasia (22\/81, 27.1%). iECoG was performed in 29 (35.8%) patients. Overall, there were no significant differences in the proportion of Engel I (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u2009.78) among those who performed iECoG (22\/29, 75.9%) and did not perform iECoG (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200941\/52, 78.8%). Among tumor\u2010associated cases, Engel I was achieved in 100% of patients with iECoG, compared with 76.5% without iECoG (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u2009.27). No significant differences were observed in focal cortical dysplasia (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u2009.61) or hippocampal sclerosis (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u2009.35).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Significance<\/jats:title>\n                    <jats:p>The study did not show that intraoperative iECoG improved Engel class I outcomes. Refinement of iECoG methods and future studies controlling for confounders are warranted.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/epd2.70160","type":"journal-article","created":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T16:10:41Z","timestamp":1768234241000},"page":"401-408","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The usefulness of intraoperative electrocorticography (\n                    <scp>iECoG<\/scp>\n                    ) in pediatric temporal lobe epilepsy surgery"],"prefix":"10.1002","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-0198-2363","authenticated-orcid":false,"given":"Rafael Andrade","family":"Cruz","sequence":"first","affiliation":[{"name":"Center of Epilepsy Surgery (CIREP), Pediatric Section, Ribeir\u00e3o Preto Medical School University of S\u00e3o Paulo  S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jo\u00e3o Paulo Sant\u2019 Ana Santos","family":"de Souza","sequence":"additional","affiliation":[{"name":"Center of Epilepsy Surgery (CIREP), Pediatric Section, Ribeir\u00e3o Preto Medical School University of S\u00e3o Paulo  S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Davi Casale","family":"Aragon","sequence":"additional","affiliation":[{"name":"Statistician, Department of Pediatrics, Ribeir\u00e3o Preto Medical School University of S\u00e3o Paulo  S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00darsula Thom\u00e9","family":"Costa","sequence":"additional","affiliation":[{"name":"Division of Neurosurgery, Department of Surgery and Anatomy, Ribeir\u00e3o Preto Medical School University of S\u00e3o Paulo  S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1884-7264","authenticated-orcid":false,"given":"Ana Paula Andrade","family":"Hamad","sequence":"additional","affiliation":[{"name":"Division of Neurosurgery, Department of Surgery and Anatomy, Ribeir\u00e3o Preto Medical School University of S\u00e3o Paulo  S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Am\u00e9rico Ceiki","family":"Sakamoto","sequence":"additional","affiliation":[{"name":"Division of Neurosurgery, Department of Surgery and Anatomy, Ribeir\u00e3o Preto Medical School University of S\u00e3o Paulo  S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ant\u00f4nio Carlos","family":"dos Santos","sequence":"additional","affiliation":[{"name":"Division of Neuroradiology, Department of Medical Imaging, Hematology and Clinical Oncology, Ribeir\u00e3o Preto Medical School University of S\u00e3o Paulo  S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H\u00e9lio Rubens","family":"Machado","sequence":"additional","affiliation":[{"name":"Center of Epilepsy Surgery (CIREP), Pediatric Section, Ribeir\u00e3o Preto Medical School University of S\u00e3o Paulo  S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcelo Volpon","family":"Santos","sequence":"additional","affiliation":[{"name":"Center of Epilepsy Surgery (CIREP), Pediatric Section, Ribeir\u00e3o Preto Medical School University of S\u00e3o Paulo  S\u00e3o Paulo Brazil"},{"name":"Division of Neurosurgery, Department of Surgery and Anatomy, Ribeir\u00e3o Preto Medical School University of S\u00e3o Paulo  S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,1,12]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/epi.16772"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.seizure.2005.03.003"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1227\/NEU.0b013e318235183d"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1088\/978-0-7503-2723-7ch2"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-95918-4_10"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s001150050543"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/epi.17472"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.119.3097.645.b"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-444-64032-1.00020-5"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.seizure.2018.11.007"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.1684\/epd.2014.0675"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2012.220"},{"key":"e_1_2_13_14_1","doi-asserted-by":"publisher","DOI":"10.1159\/000056036"},{"key":"e_1_2_13_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/epi.18302"},{"key":"e_1_2_13_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2024.09.004"},{"key":"e_1_2_13_17_1","doi-asserted-by":"publisher","DOI":"10.3345\/kjp.2013.56.7.275"},{"key":"e_1_2_13_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00381-014-2459-7"},{"key":"e_1_2_13_19_1","doi-asserted-by":"publisher","DOI":"10.3171\/2020.4.PEDS20198"},{"key":"e_1_2_13_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1059-1311(03)00095-5"},{"key":"e_1_2_13_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00381-010-1279-7"},{"key":"e_1_2_13_22_1","doi-asserted-by":"publisher","DOI":"10.1177\/088307389901400102"},{"key":"e_1_2_13_23_1","doi-asserted-by":"publisher","DOI":"10.1159\/000120897"},{"key":"e_1_2_13_24_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000209430"},{"key":"e_1_2_13_25_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006123-199702000-00014"}],"container-title":["Epileptic 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