{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,12]],"date-time":"2026-07-12T03:48:19Z","timestamp":1783828099480,"version":"3.55.0"},"reference-count":16,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,1,10]],"date-time":"2026-01-10T00:00:00Z","timestamp":1768003200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,10]],"date-time":"2026-01-10T00:00:00Z","timestamp":1768003200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001665","name":"Agence Nationale de la Recherche","doi-asserted-by":"publisher","award":["ANR\u201016\u2010CONV000X"],"award-info":[{"award-number":["ANR\u201016\u2010CONV000X"]}],"id":[{"id":"10.13039\/501100001665","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001665","name":"Agence Nationale de la Recherche","doi-asserted-by":"publisher","award":["ANR\u201017\u2010EURE\u20100029"],"award-info":[{"award-number":["ANR\u201017\u2010EURE\u20100029"]}],"id":[{"id":"10.13039\/501100001665","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001665","name":"Agence Nationale de la Recherche","doi-asserted-by":"publisher","award":["ANR\u201019\u2010CE37\u20100027"],"award-info":[{"award-number":["ANR\u201019\u2010CE37\u20100027"]}],"id":[{"id":"10.13039\/501100001665","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Epileptic Disorders"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Epilepsy surgery remains the most effective treatment for focal drug\u2010resistant epilepsy, and stereoelectroencephalography (SEEG) is increasingly used to define the epileptogenic\u2010zone network (EZN) and guide curative or palliative interventions. While SEEG is considered a safe invasive procedure, adverse events arising during monitoring itself are rarely described. We report three exceptional cases of postictal self\u2010removal of intracerebral electrodes during SEEG monitoring. Among 591 implanted patients between January 2000 and October 2025 at Timone Hospital, Marseille, three patients (0.5%) met the inclusion criteria. All were young right\u2010handed men with normal neurocognitive development, focal drug\u2010resistant epilepsy and no psychiatric comorbidity. Self\u2010removal occurred during the postictal phase of spontaneous seizures\u2014two following focal\u2010to\u2010bilateral tonic\u2013clonic seizures and one after a focal impaired\u2010awareness seizure\u2014on the second day of monitoring under complete or partial antiseizure medication withdrawal. Postictal behavior was characterized by agitation, wandering, and, in two cases, resistive aggression when nursing staff attempted to intervene. None of the patients sustained neurological sequelae or significant cerebrovascular complications. EZN involved the temporal lobe in all cases. These observations illustrate that postictal confusion, particularly under medication withdrawal, may occasionally manifest as resistive behavior capable of causing self\u2010harm by means of device manipulation. Awareness of this rare, but potentially hazardous phenomenon, identification of at\u2010risk patients, and implementation of tailored preventive measures may help improve the safety of invasive epilepsy monitoring.<\/jats:p>","DOI":"10.1002\/epd2.70175","type":"journal-article","created":{"date-parts":[[2026,1,10]],"date-time":"2026-01-10T09:21:34Z","timestamp":1768036894000},"page":"488-495","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Postictal self\u2010removal of intracerebral electrodes during stereoelectroencephalography monitoring: A case series"],"prefix":"10.1002","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8978-8927","authenticated-orcid":false,"given":"Ionu\u021b\u2010Flavius","family":"Bratu","sequence":"first","affiliation":[{"name":"Assistance Publique\u2014H\u00f4pitaux de Marseille, Epileptology and Cerebral Rhythmology Department, Timone Hospital  Marseille France"},{"name":"Systems Neuroscience Institute, French National Institute of Health and Medical Research (UMR 1106), Aix\u2010Marseille University  Marseille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Romain","family":"Carron","sequence":"additional","affiliation":[{"name":"Systems Neuroscience Institute, French National Institute of Health and Medical Research (UMR 1106), Aix\u2010Marseille University  Marseille France"},{"name":"Assistance Publique\u2014H\u00f4pitaux de Marseille, Medico\u2010Surgical Unit of Epileptology, Functional and Stereotactic Neurosurgery, Timone Hospital  Marseille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7962-2942","authenticated-orcid":false,"given":"Julia","family":"Makhalova","sequence":"additional","affiliation":[{"name":"Assistance Publique\u2014H\u00f4pitaux de Marseille, Epileptology and Cerebral Rhythmology Department, Timone Hospital  Marseille France"},{"name":"Systems Neuroscience Institute, French National Institute of Health and Medical Research (UMR 1106), Aix\u2010Marseille University  Marseille France"},{"name":"Center for Magnetic Resonance in Biology and Medicine, National Centre for Scientific Research (UMR 7339), Aix\u2010Marseille University  Marseille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stanislas","family":"Lagarde","sequence":"additional","affiliation":[{"name":"Assistance Publique\u2014H\u00f4pitaux de Marseille, Epileptology and Cerebral Rhythmology Department, Timone Hospital  Marseille France"},{"name":"Systems Neuroscience Institute, French National Institute of Health and Medical Research (UMR 1106), Aix\u2010Marseille University  Marseille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1678-0297","authenticated-orcid":false,"given":"Fabrice","family":"Bartolomei","sequence":"additional","affiliation":[{"name":"Assistance Publique\u2014H\u00f4pitaux de Marseille, Epileptology and Cerebral Rhythmology Department, Timone Hospital  Marseille France"},{"name":"Systems Neuroscience Institute, French National Institute of Health and Medical Research (UMR 1106), Aix\u2010Marseille University  Marseille France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,1,10]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000003407"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/epd2.20190"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/WCO.0000000000001351"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neucli.2017.11.005"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neucli.2017.11.007"},{"key":"e_1_2_10_7_1","first-page":"1","article-title":"Antiseizure medication reduction in long\u2010term video\u2010electroencephalographic monitoring for presurgical evaluation: a multicenter safety and efficacy analysis","volume":"1","author":"Griethuysen R","year":"2025","journal-title":"Epilepsia"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yebeh.2010.06.038"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000113763.11862.26"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yebeh.2010.06.018"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1684\/epd.2017.0925"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/epi.13298"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yebeh.2024.109806"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/epd2.20023"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2020.05.029"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yebeh.2023.109448"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-244X-14-75"}],"container-title":["Epileptic Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/epd2.70175","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/epd2.70175","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/epd2.70175","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T06:43:53Z","timestamp":1776321833000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/epd2.70175"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,10]]},"references-count":16,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,4]]}},"alternative-id":["10.1002\/epd2.70175"],"URL":"https:\/\/doi.org\/10.1002\/epd2.70175","archive":["Portico"],"relation":{},"ISSN":["1294-9361","1950-6945"],"issn-type":[{"value":"1294-9361","type":"print"},{"value":"1950-6945","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,10]]},"assertion":[{"value":"2025-11-17","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication 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