{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T11:51:29Z","timestamp":1791287489023,"version":"4.1.0"},"reference-count":57,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T00:00:00Z","timestamp":1791244800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T00:00:00Z","timestamp":1791244800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Epileptic Disorders"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Epilepsy significantly affects daily functioning and health\u2010related quality of life (HRQOL) of those living with the condition. Less is known about HRQOL of family caregivers of adults with epilepsy, yet the functioning of patients and caregivers is interlinked, and caregivers' unmet support needs are high. A consensus\u2010based core outcome set for caregivers' HRQOL can guide more structured caregiver assessments and aid timely intervention.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A three\u2010round Delphi study was conducted to determine outcomes most important for family caregivers' HRQOL. Three stakeholder groups were recruited: experts\u2010by\u2010experience (caregivers\/adults with epilepsy), healthcare professionals, and researchers. Across two survey rounds, participants rated outcomes for relevance, feasibility, and amenability to change. A predefined consensus threshold (\u226580% agreement on relevance) guided outcome selection. In round three, participants prioritized three relevant outcomes per HRQOL domain. The resulting preliminary core outcome set was reviewed by a second stakeholder panel for scope, overlap, and feasibility before finalizing.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Thirty\u2010four experts\u2010by\u2010experience, healthcare professionals, and researchers from 10 countries participated. In rounds 1 (\n                      <jats:italic>N<\/jats:italic>\n                      \u2009=\u200934) and 2 (\n                      <jats:italic>N<\/jats:italic>\n                      \u2009=\u200932), 41 outcomes reached the \u226580% relevance threshold and were retained. In round 3 (\n                      <jats:italic>N<\/jats:italic>\n                      \u2009=\u200930), participants prioritized 18 outcomes. After review by the second panel (\n                      <jats:italic>N<\/jats:italic>\n                      \u2009=\u200925), the final core outcome set includes caregivers' physical functioning (general health, sleep, fatigue), emotional functioning (emotional (in)stability, seizure worry, overwhelm, resilience), social functioning (personal relationships, family relationships, social stigma), spiritual\/religious functioning (hope, purpose\/meaning), tasks\/responsibilities (understanding diagnosis and treatment, coping with behavior changes), and self\u2010care, respite, and financial security. We recommend outcome measures prioritized for good psychometric properties, language availability, and low burden of administration to facilitate caregiver assessments.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Significance<\/jats:title>\n                    <jats:p>This international Delphi consensus study established 18 core outcomes for HRQOL of caregivers of adults with epilepsy. Structured assessment of the core outcome set using validated tools can support timely detection of and intervention to alleviate HRQOL issues in caregivers.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/epd2.70413","type":"journal-article","created":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T11:00:37Z","timestamp":1791284437000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Core outcome set for quality of life of family caregivers of adults with epilepsy: A Delphi consensus study"],"prefix":"10.1002","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0409-7949","authenticated-orcid":false,"given":"Florien","family":"Boele","sequence":"first","affiliation":[{"name":"Stichting Epilepsie Instellingen Nederland (SEIN)  Heemstede SW the Netherlands"},{"name":"Leeds Institute of Medical Research at St James's St James's University Hospital, University of Leeds  Leeds UK"},{"name":"Leeds Institute of Health Sciences, Faculty of Medicine and Health University of Leeds  Leeds UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Famke","family":"Visser","sequence":"additional","affiliation":[{"name":"Stichting Epilepsie Instellingen Nederland (SEIN)  Heemstede SW the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1258-5678","authenticated-orcid":false,"given":"Maeike","family":"Zijlmans","sequence":"additional","affiliation":[{"name":"Stichting Epilepsie Instellingen Nederland (SEIN)  Heemstede SW the Netherlands"},{"name":"Brain Center Rudolf Magnus UMC Utrecht  Utrecht CX the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1113-4210","authenticated-orcid":false,"given":"Maaike","family":"Schuur","sequence":"additional","affiliation":[{"name":"Stichting Epilepsie Instellingen Nederland (SEIN)  Heemstede SW the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephanie","family":"Peters","sequence":"additional","affiliation":[{"name":"Stichting Epilepsie Instellingen Nederland (SEIN)  Heemstede SW the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0337-3449","authenticated-orcid":false,"given":"Francis","family":"Saridin","sequence":"additional","affiliation":[{"name":"Stichting Epilepsie Instellingen Nederland (SEIN)  Heemstede SW the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4809-3034","authenticated-orcid":false,"given":"Lydia","family":"van den Berg","sequence":"additional","affiliation":[{"name":"Stichting Epilepsie Instellingen Nederland (SEIN)  Heemstede SW the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-3139-6323","authenticated-orcid":false,"given":"Aysun","family":"Altinbas","sequence":"additional","affiliation":[{"name":"Stichting Epilepsie Instellingen Nederland (SEIN)  Heemstede SW the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1935-7603","authenticated-orcid":false,"given":"Rolf","family":"Fronczek","sequence":"additional","affiliation":[{"name":"Stichting Epilepsie Instellingen Nederland (SEIN)  Heemstede SW the Netherlands"},{"name":"Department of Neurology Leiden University Medical Center  Leiden ZA the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1435-8970","authenticated-orcid":false,"given":"Roland","family":"Thijs","sequence":"additional","affiliation":[{"name":"Stichting Epilepsie Instellingen Nederland (SEIN)  Heemstede SW the Netherlands"},{"name":"Department of Neurology Leiden University Medical Center  Leiden ZA the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2257-3147","authenticated-orcid":false,"given":"Jaap C.","family":"Reijneveld","sequence":"additional","affiliation":[{"name":"Stichting Epilepsie Instellingen Nederland (SEIN)  Heemstede SW the Netherlands"},{"name":"Department of Neurology Amsterdam UMC  Amsterdam AZ the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,6]]},"reference":[{"issue":"3","key":"e_1_2_12_2_1","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1212\/WNL.0000000000003509","article-title":"Prevalence and incidence of epilepsy","volume":"88","author":"Fiest KM","year":"2017","journal-title":"Neurology"},{"issue":"1","key":"e_1_2_12_3_1","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/S1474-4422(15)00225-2","article-title":"Comorbidities of epilepsy: current concepts and future perspectives","volume":"15","author":"Keezer MR","year":"2016","journal-title":"Lancet Neurol"},{"key":"e_1_2_12_4_1","doi-asserted-by":"crossref","DOI":"10.1016\/j.yebeh.2023.109179","article-title":"The impact of epilepsy on quality of life: findings from a European survey","volume":"142","author":"Strzelczyk A","year":"2023","journal-title":"Epilepsy Behav"},{"key":"e_1_2_12_5_1","unstructured":"ISOQOL.What is quality of life?www.isoqol.org\/what\u2010is\u2010qol\/"},{"key":"e_1_2_12_6_1","doi-asserted-by":"crossref","DOI":"10.1016\/j.yebeh.2025.110601","article-title":"Health\u2010related quality of life and unmet needs of people with epilepsy and their family caregivers: a systematic scoping review","volume":"171","author":"Boele F","year":"2025","journal-title":"Epilepsy Behav"},{"issue":"1","key":"e_1_2_12_7_1","first-page":"1","article-title":"Caregivers' knowledge on epilepsy and its relationship with quality of life","volume":"5","author":"Khuan L","year":"2023","journal-title":"Eur J Med Health Sci"},{"key":"e_1_2_12_8_1","doi-asserted-by":"crossref","DOI":"10.1016\/j.yebeh.2021.107768","article-title":"Determinants of caregiver burden in male patients with epilepsy following penetrating traumatic brain injury","volume":"116","author":"Jabbarinejad R","year":"2021","journal-title":"Epilepsy Behav"},{"key":"e_1_2_12_9_1","doi-asserted-by":"crossref","DOI":"10.1016\/j.yebeh.2021.108319","article-title":"A journey into the unknown: an ethnographic examination of drug\u2010resistant epilepsy treatment and management in the United States","volume":"124","author":"Watson GDR","year":"2021","journal-title":"Epilepsy Behav"},{"issue":"2","key":"e_1_2_12_10_1","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1111\/epi.16429","article-title":"The economic burden of caregiving in epilepsy: an estimate based on a survey of US caregivers","volume":"61","author":"Hussain SA","year":"2020","journal-title":"Epilepsia"},{"key":"e_1_2_12_11_1","doi-asserted-by":"crossref","DOI":"10.1016\/j.yebeh.2023.109151","article-title":"Caregiver burden and COVID\u201019: how epilepsy caregivers experienced the pandemic","volume":"141","author":"Viny M","year":"2023","journal-title":"Epilepsy Behav"},{"issue":"1","key":"e_1_2_12_12_1","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/1059-1311(92)90054-5","article-title":"The impact of chronic epilepsy on the family","volume":"1","author":"Thompson PJ","year":"1992","journal-title":"Seizure"},{"issue":"6","key":"e_1_2_12_13_1","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1097\/NRL.0000000000000140","article-title":"Burden of seizure clusters on patients with epilepsy and caregivers","volume":"22","author":"Penovich PE","year":"2017","journal-title":"Neurologist"},{"issue":"4","key":"e_1_2_12_14_1","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1016\/j.yebeh.2012.10.003","article-title":"Testimonies submitted for the Institute of Medicine report","volume":"25","author":"Austin JK","year":"2012","journal-title":"Epilepsy Behav"},{"key":"e_1_2_12_15_1","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.yebeh.2018.11.015","article-title":"High risk of anxiety and depression in caregivers of adult patients with epilepsy and its negative impact on patients' quality of life","volume":"90","author":"Zhu X","year":"2019","journal-title":"Epilepsy Behav"},{"key":"e_1_2_12_16_1","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.yebeh.2018.03.008","article-title":"A systematic review of quality of life in parents of children with epilepsy","volume":"82","author":"Puka K","year":"2018","journal-title":"Epilepsy Behav"},{"issue":"7","key":"e_1_2_12_17_1","doi-asserted-by":"crossref","first-page":"1916","DOI":"10.1111\/epi.17971","article-title":"Development of an international standard set of outcomes and measurement methods for routine practice for adults with epilepsy: the international consortium for health outcomes measurement consensus recommendations","volume":"65","author":"Mitchell JW","year":"2024","journal-title":"Epilepsia"},{"issue":"8","key":"e_1_2_12_18_1","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2024.24793","article-title":"Patient\u2010reported outcome measures in cancer care","volume":"7","author":"Balitsky AK","year":"2024","journal-title":"JAMA Netw Open"},{"issue":"7","key":"e_1_2_12_19_1","doi-asserted-by":"crossref","first-page":"1938","DOI":"10.1111\/epi.17976","article-title":"Development of an international standard set of outcomes and measurement methods for routine practice for infants, children, and adolescents with epilepsy: the international consortium for health outcomes measurement consensus recommendations","volume":"65","author":"Mitchell JW","year":"2024","journal-title":"Epilepsia"},{"issue":"4","key":"e_1_2_12_20_1","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.1046\/j.1365-2648.2000.t01-1-01567.x","article-title":"Research guidelines for the Delphi survey technique","volume":"32","author":"Hasson F","year":"2000","journal-title":"J Adv Nurs"},{"issue":"2","key":"e_1_2_12_21_1","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/S0020-7489(00)00044-4","article-title":"A critical review of the Delphi technique as a research methodology for nursing","volume":"38","author":"Keeney S","year":"2001","journal-title":"Int J Nurs Stud"},{"issue":"6","key":"e_1_2_12_22_1","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0020476","article-title":"Using and reporting the Delphi method for selecting healthcare quality indicators: a systematic review","volume":"6","author":"Boulkedid R","year":"2011","journal-title":"PLoS One"},{"issue":"6","key":"e_1_2_12_23_1","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1080\/08870446.2016.1139112","article-title":"Caregiving in multiple sclerosis and quality of life: a meta\u2010synthesis of qualitative research","volume":"31","author":"Topcu G","year":"2016","journal-title":"Psychol Health"},{"issue":"8","key":"e_1_2_12_24_1","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1080\/13607863.2014.915921","article-title":"Self\u2010efficacy and health\u2010related quality of life in family carers of people with dementia: a systematic review","volume":"18","author":"Crellin NE","year":"2014","journal-title":"Aging Ment Health"},{"issue":"1","key":"e_1_2_12_25_1","doi-asserted-by":"crossref","DOI":"10.1002\/gps.5870","article-title":"The impact of caregiving on quality of life in Parkinson's disease: a systematic review","volume":"38","author":"Perepezko K","year":"2023","journal-title":"Int J Geriatr Psychiatry"},{"issue":"6","key":"e_1_2_12_26_1","first-page":"465","article-title":"Family caregiver constructs and outcome measures in neuro\u2010oncology: a systematic review","volume":"9","author":"Boele F","year":"2022","journal-title":"Neurooncol Pract"},{"issue":"7","key":"e_1_2_12_27_1","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1007\/s40273-016-0389-9","article-title":"Health, health\u2010related quality of life, and quality of life: what is the difference?","volume":"34","author":"Karimi M","year":"2016","journal-title":"PharmacoEconomics"},{"issue":"4","key":"e_1_2_12_28_1","first-page":"438","article-title":"Caregiver burden: a concept analysis","volume":"7","author":"Liu Z","year":"2020","journal-title":"Int J Nurs Sci"},{"issue":"10","key":"e_1_2_12_29_1","doi-asserted-by":"crossref","DOI":"10.1016\/j.arthro.2025.03.038","article-title":"Guidelines for designing and conducting Delphi consensus studies: an expert consensus Delphi study","volume":"41","author":"Hohmann E","year":"2025","journal-title":"Arthroscopy"},{"issue":"4","key":"e_1_2_12_30_1","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/j.jclinepi.2013.12.002","article-title":"Defining consensus: a systematic review recommends methodologic criteria for reporting of Delphi studies","volume":"67","author":"Diamond IR","year":"2014","journal-title":"J Clin Epidemiol"},{"issue":"1","key":"e_1_2_12_31_1","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1002\/epi4.70170","article-title":"Self\u2010completed patient\u2010reported outcome measures in adults with epilepsy: a review","volume":"11","author":"Conquest AL","year":"2026","journal-title":"Epilepsia Open"},{"issue":"9","key":"e_1_2_12_32_1","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2021-051066","article-title":"Patient participation in Delphi surveys to develop core outcome sets: systematic review","volume":"11","author":"Barrington H","year":"2021","journal-title":"BMJ Open"},{"issue":"1","key":"e_1_2_12_33_1","doi-asserted-by":"crossref","DOI":"10.1186\/s13063-025-09149-2","article-title":"Methodological guidance for incorporating lived experience in the early stages of core outcome set development: a scoping review protocol","volume":"26","author":"Livingston MK","year":"2025","journal-title":"Trials"},{"key":"e_1_2_12_34_1","doi-asserted-by":"crossref","DOI":"10.1016\/j.jclinepi.2024.111485","article-title":"Sample size in multistakeholder Delphi surveys: at what minimum sample size do replicability of results stabilize?","volume":"174","author":"Manyara AM","year":"2024","journal-title":"J Clin Epidemiol"},{"issue":"11","key":"e_1_2_12_35_1","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2020-040223","article-title":"Systematic review of international Delphi surveys for core outcome set development: representation of international patients","volume":"10","author":"Lee A","year":"2020","journal-title":"BMJ Open"},{"key":"e_1_2_12_36_1","doi-asserted-by":"crossref","DOI":"10.1016\/j.yebeh.2024.110260","article-title":"Burden in caregivers of adults with epilepsy: a critical review","volume":"164","author":"Poprelka K","year":"2025","journal-title":"Epilepsy Behav"},{"key":"e_1_2_12_37_1","doi-asserted-by":"crossref","DOI":"10.1016\/j.yebeh.2025.110262","article-title":"Caregiving burden for adults with epilepsy and coping strategies, a systematic review","volume":"164","author":"Yu X","year":"2025","journal-title":"Epilepsy Behav"},{"key":"e_1_2_12_38_1","doi-asserted-by":"crossref","DOI":"10.1136\/esmoopen-2020-000837","article-title":"Sex\u2010specific and gender\u2010specific aspects in patient\u2010reported outcomes","volume":"5","author":"Hertler C","year":"2020","journal-title":"ESMO Open"},{"issue":"6","key":"e_1_2_12_39_1","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1007\/s11136-005-5994-6","article-title":"The CarerQol instrument: a new instrument to measure care\u2010related quality of life of informal caregivers for use in economic evaluations","volume":"15","author":"Brouwer WBF","year":"2006","journal-title":"Qual Life Res"},{"issue":"6","key":"e_1_2_12_40_1","doi-asserted-by":"crossref","DOI":"10.3390\/jcm14061916","article-title":"The CarerQol instrument: a systematic review, validity analysis, and generalization reliability study","volume":"14","author":"Cejalvo E","year":"2025","journal-title":"J Clin Med"},{"issue":"9","key":"e_1_2_12_41_1","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1097\/01.NAJ.0000334528.90459.9a","article-title":"Helping those who help others","volume":"108","author":"Onega LL","year":"2008","journal-title":"Am J Nurs"},{"issue":"2","key":"e_1_2_12_42_1","doi-asserted-by":"crossref","first-page":"S127","DOI":"10.1093\/geronb\/58.2.S127","article-title":"Analysis of the reliability of the modified caregiver strain index","volume":"58","author":"Thornton M","year":"2003","journal-title":"J Gerontol B Psychol Sci Soc Sci"},{"key":"e_1_2_12_43_1","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.yebeh.2016.01.036","article-title":"Which outcomes should we measure in adult epilepsy trials? The views of people with epilepsy and informal carers","volume":"59","author":"Noble AJ","year":"2016","journal-title":"Epilepsy Behav"},{"issue":"1","key":"e_1_2_12_44_1","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1177\/1937586719887709","article-title":"We agree, Don't we? The Delphi method for health environments research","volume":"13","author":"Taylor E","year":"2020","journal-title":"HERD: Health Environ Res Des J"},{"issue":"1","key":"e_1_2_12_45_1","doi-asserted-by":"crossref","DOI":"10.1186\/s12913-019-4394-5","article-title":"Towards a universal model of family centered care: a scoping review","volume":"19","author":"Kokorelias KM","year":"2019","journal-title":"BMC Health Serv Res"},{"issue":"2","key":"e_1_2_12_46_1","first-page":"573","article-title":"Patient outcomes, patient experiences and process indicators associated with the routine use of patient\u2010reported outcome measures (PROMs) in cancer care: a systematic review","volume":"29","author":"Graupner C","year":"2021","journal-title":"Support Care Cancer"},{"issue":"1","key":"e_1_2_12_47_1","doi-asserted-by":"crossref","DOI":"10.1186\/s41687-023-00578-8","article-title":"Effectiveness of routine provision of feedback from patient\u2010reported outcome measurements for cancer care improvement: a systematic review and meta\u2010analysis","volume":"7","author":"Lu S\u2010C","year":"2023","journal-title":"J Patient Rep Outcomes"},{"issue":"1","key":"e_1_2_12_48_1","doi-asserted-by":"crossref","DOI":"10.1038\/srep29281","article-title":"The efficacy and cost\u2010effectiveness of stepped care prevention and treatment for depressive and\/or anxiety disorders: a systematic review and meta\u2010analysis","volume":"6","author":"Ho FY\u2010Y","year":"2016","journal-title":"Sci Rep"},{"issue":"5","key":"e_1_2_12_49_1","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1002\/cncr.30428","article-title":"Family caregivers' level of mastery predicts survival of patients with glioblastoma: a preliminary report","volume":"123","author":"Boele FW","year":"2017","journal-title":"Cancer"},{"issue":"1","key":"e_1_2_12_50_1","doi-asserted-by":"crossref","DOI":"10.1186\/s40900-018-0091-5","article-title":"Defining and evaluating novel procedures for involving patients in Core outcome set research: creating a meaningful long list of candidate outcome domains","volume":"4","author":"Smith H","year":"2018","journal-title":"Res Involv Engagem"},{"issue":"3","key":"e_1_2_12_51_1","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0172937","article-title":"A review of patient and carer participation and the use of qualitative research in the development of core outcome sets","volume":"12","author":"Jones JE","year":"2017","journal-title":"PLoS One"},{"issue":"5","key":"e_1_2_12_52_1","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1111\/j.1528-1167.2010.02973.x","article-title":"Relationship of clinical and quality of life trajectories following the onset of seizures: findings from the UK MESS study","volume":"52","author":"Jacoby A","year":"2011","journal-title":"Epilepsia"},{"issue":"3","key":"e_1_2_12_53_1","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/j.yebeh.2011.04.002","article-title":"Levels of epilepsy stigma in an incident population and associated factors","volume":"21","author":"Taylor J","year":"2011","journal-title":"Epilepsy Behav"},{"issue":"5","key":"e_1_2_12_54_1","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1370\/afm.89","article-title":"The spirituality index of well\u2010being: a new instrument for health\u2010related quality\u2010of\u2010life research","volume":"2","author":"Daaleman TP","year":"2004","journal-title":"Ann Fam Med"},{"issue":"4","key":"e_1_2_12_55_1","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1007\/s001270050039","article-title":"Measurement of risk for mental disorders and competence in a psychiatric epidemiologic community survey: the National Institute of Mental Health methods for the epidemiology of child and adolescent mental disorders (MECA) study","volume":"33","author":"Goodman SH","year":"1998","journal-title":"Soc Psychiatry Psychiatr Epidemiol"},{"issue":"6","key":"e_1_2_12_56_1","first-page":"1231","article-title":"The family APGAR: a proposal for a family function test and its use by physicians","volume":"6","author":"Smilkstein G","year":"1978","journal-title":"J Fam Pract"},{"issue":"8","key":"e_1_2_12_57_1","first-page":"588","article-title":"Brief questions to identify patients with inadequate health literacy","volume":"36","author":"Chew L","year":"2004","journal-title":"Fam Med"},{"issue":"1","key":"e_1_2_12_58_1","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1007\/s11606-013-2568-0","article-title":"Psychometric properties of the brief health literacy screen in clinical practice","volume":"29","author":"Wallston KA","year":"2014","journal-title":"J Gen Intern Med"}],"container-title":["Epileptic Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/epd2.70413","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/epd2.70413","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/epd2.70413","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T11:00:45Z","timestamp":1791284445000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/epd2.70413"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10,6]]},"references-count":57,"alternative-id":["10.1002\/epd2.70413"],"URL":"https:\/\/doi.org\/10.1002\/epd2.70413","archive":["Portico"],"relation":{},"ISSN":["1294-9361","1950-6945"],"issn-type":[{"value":"1294-9361","type":"print"},{"value":"1950-6945","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10,6]]},"assertion":[{"value":"2026-06-26","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-07","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-10-06","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"epd2.70413"}}