{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T02:35:05Z","timestamp":1783132505866,"version":"3.54.6"},"reference-count":56,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T00:00:00Z","timestamp":1773878400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T00:00:00Z","timestamp":1773878400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Epilepsia"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This cohort study examined the agreement between youth\u2010 and parent\u2010reported health\u2010related quality of life (HRQOL) of children treated with epilepsy surgery compared to medical therapy. A second aim was to evaluate whether changes in HRQOL over 2\u2009years differed between the two groups, and to determine whether these trajectories differed by informant (youth or parent).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A total of 255 youth\u2013parent dyads participated, of whom 95 youth underwent epilepsy surgery and 160 continued medical management. Participants completed the KIDSCREEN\u201027 at baseline, 6\u2010month, 1\u2010year, and 2\u2010year follow\u2010up. Youth\u2013parent agreement was evaluated at the individual level as well as at the group level. Linear mixed models were used to evaluate changes in HRQOL over time.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among 255 youth, 46% were female, and ages ranged from 8 to 18\u2009years (mean 13\u2009years) at baseline. Most parents were female (85%) and 40\u201349\u2009years of age (58%). The surgical and medical group were largely similar across baseline characteristics. Agreement across HRQOL domains ranged from fair to good intraclass correlation coefficient (ICC .32\u2013.66). Although average youth\u2013parent differences were small (\u22121 to +3 points), Bland\u2013Altman plots showed large discrepancies, and substantial differences between dyads were frequent. Youth reported increasing Physical Well\u2010being and School Environment scores in the first year after surgery and remaining stable or slightly decreasing thereafter. In contrast, parent\u2010reported trajectories for Physical Well\u2010being and School Environment did not show a significant difference. For other domains\u2014Psychological Well\u2010being, Autonomy and Parent Relation, and Social Support and Peers\u2014no differences were identified across treatment groups, and findings were consistent among youth and parent reports.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Significance<\/jats:title>\n                    <jats:p>The results emphasize the need for considering the perspective of youth as well as their parents when evaluating the outcomes of surgery or other treatments for epilepsy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/epi.70201","type":"journal-article","created":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T15:00:53Z","timestamp":1773932453000},"page":"2783-2795","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Agreement and 2\u2010year trajectories of youth\u2010 and parent\u2010reported health\u2010related quality of life in youth with epilepsy treated with surgery vs medical therapy"],"prefix":"10.1002","volume":"67","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1937-1026","authenticated-orcid":false,"given":"Mary Lou","family":"Smith","sequence":"first","affiliation":[{"name":"Neuroscience and Mental Health Program The Hospital for Sick Children  Toronto Ontario Canada"},{"name":"Department of Psychology University of Toronto Mississauga  Mississauga Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7763-988X","authenticated-orcid":false,"given":"Klajdi","family":"Puka","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics Western University  London Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0986-5476","authenticated-orcid":false,"given":"Elysa","family":"Widjaja","sequence":"additional","affiliation":[{"name":"Neuroscience and Mental Health Program The Hospital for Sick Children  Toronto Ontario Canada"},{"name":"Department of Radiology Ann &amp; Robert H Lurie Children's Hospital  Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,3,19]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0924\u20109338(97)89095\u20105"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/jpepsy\/21.2.175"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0013\u20109580.2005.66104.x"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528\u20101167.2011.03121.x"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1528\u20101157.2003.48202.x"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000008966"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/neuros\/nyy471"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2023.4858"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/epi.17660"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.5152\/TurkArchPediatr.2022.21173"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yebeh.2008.12.008"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/epi.13774"},{"key":"e_1_2_13_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/epi.16579"},{"key":"e_1_2_13_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/epi.16665"},{"key":"e_1_2_13_16_1","doi-asserted-by":"publisher","DOI":"10.1006\/ebeh.2000.0129"},{"key":"e_1_2_13_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/epi.13441"},{"key":"e_1_2_13_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/epi.12772"},{"key":"e_1_2_13_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.seizure.2023.08.016"},{"key":"e_1_2_13_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2007.11.008"},{"key":"e_1_2_13_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbi.2008.08.010"},{"key":"e_1_2_13_22_1","volume-title":"The KIDSCREEN questionnaires \u2010 quality of life questionnaires for children and adolescents. 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