{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T08:42:49Z","timestamp":1792226569457,"version":"4.4.0"},"reference-count":38,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:00:00Z","timestamp":1787011200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:00:00Z","timestamp":1787011200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Epilepsia"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>The Dravet Disease\u2010Associated Neuropsychiatric Disorders (D\u2010DAND) scale is a new caregiver\u2010administered interview designed to assess the wide range of developmental and behavioral comorbidities in Dravet syndrome (DS) beyond seizures. D\u2010DAND's preliminary psychometric properties in a large patient sample are reported.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>D\u2010DAND was developed by a panel of experts and later standardized with caregivers of 123 individuals with DS (age\u2009=\u20093\u201341\u2009years); a subsample of 43 caregivers were interviewed twice (~2\u2009weeks apart) to evaluate test\u2013retest reliability; another subsample of 80 were also administered with other scales that are widely used despite not being tailored to DS (Vineland Adaptive Behavior Scales, Child Behavior Checklist, Childhood Autism Rating Scale, Behavior Rating Inventory of Executive Function, Sleep Disturbance Scale for Children).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The D\u2010DAND captured a broad spectrum of abilities and dysfunctions across multiple functional domains. Test\u2013retest reliability was excellent (overall score:\n                      <jats:italic>r<\/jats:italic>\n                      \u2009\u2248\u2009.98, median across domains:\n                      <jats:italic>r<\/jats:italic>\n                      \u2009\u2248\u2009.89), thus allowing for high sensitivity to time\u2010related changes. As expected, D\u2010DAND scores showed high correlations with some standardized measures (e.g., Vineland scales) and low correlation with others, suggesting that D\u2010DAND measures unique, Dravet\u2010specific features that other, widely used tools fail to detect.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Significance<\/jats:title>\n                    <jats:p>D\u2010DAND is a novel, reliable tool for comprehensive evaluation of DS beyond seizures. It enables systematic tracking of developmental and behavioral issues in DS, facilitating early identification of needs and more personalized, whole\u2010person care.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/epi.70399","type":"journal-article","created":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:46:35Z","timestamp":1787067995000},"page":"5325-5339","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Introducing the D\u2010\n                    <scp>DAND<\/scp>\n                    scale: Development of a comprehensive caregiver\u2010administered tool for Dravet syndrome comorbidities"],"prefix":"10.1002","volume":"67","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8740-4686","authenticated-orcid":false,"given":"Bernardo","family":"Dalla Bernardina","sequence":"first","affiliation":[{"name":"Research Center for Pediatric Epilepsies Azienda Ospedaliera Universitaria Integrata of Verona  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