{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T11:32:07Z","timestamp":1782732727316,"version":"3.54.5"},"reference-count":22,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2023,8,10]],"date-time":"2023-08-10T00:00:00Z","timestamp":1691625600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004504","name":"Lietuvos Mokslo Taryba","doi-asserted-by":"publisher","award":["P\u2010SV\u201022\u201033"],"award-info":[{"award-number":["P\u2010SV\u201022\u201033"]}],"id":[{"id":"10.13039\/501100004504","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Epilepsia Open"],"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To compare forgetting patterns between patients with temporal lobe (TLE) and generalized (GGE) epilepsies and to assess whether recall is associated with epileptic activity.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Thirty\u2010three patients with TLE (13 left, 17 right, and 3 nonlateralized TLE), 42 patients with GGE, and 57 healthy controls (HCs) were asked to recall words, verbal story material, and the Rey\u2010Osterrieth complex figure at two delays. Accelerated long\u2010term forgetting (ALF) was defined by group performance comparable to HCs at 30\u2009min and worse recall than HCs after 4\u2009weeks. ALF was assessed by comparing raw test scores in a two\u2010way repeated measures analysis of variance (ANOVA) adjusted for the learning capacity.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Compared to HCs, patients with R\u2010TLE remembered fewer items of the word list after 30\u2009min as well as after 4\u2009weeks. Patients with L\u2010TLE and GGE had comparable learning\u2010adjusted performance to HCs at the 30\u2009min delay but scored less after 4\u2009weeks (group by delay interaction <jats:italic>F<\/jats:italic>(3, 124)\u2009=\u20093.2, <jats:italic>P<\/jats:italic>\u2009=\u20090.026, \u2009=\u20090.07). The epilepsy group (patients with TLE and GGE combined) performed as well as HCs at 30\u2009min but worse after 4\u2009weeks irrespective of experienced seizures during the 4\u2010week delay or interictal bilateral (TLE) or generalized (GGE) activity before the study. We noted no statistically significant differences between patient and HC verbal story (group by delay interaction <jats:italic>F<\/jats:italic>(3, 124)\u2009=\u20090.7, <jats:italic>P<\/jats:italic>\u2009=\u20090.570, \u2009=\u20090.02) or complex figure (<jats:italic>F<\/jats:italic>(3, 124)\u2009=\u20090.8, <jats:italic>P<\/jats:italic>\u2009=\u20090.488, \u2009=\u20090.02) recall.<\/jats:p><\/jats:sec><jats:sec><jats:title>Significance<\/jats:title><jats:p>Our data support verbal and visual memory impairment in both TLE and GGE with different performances between these groups in the task of word recall. We suggest the presence of ALF in patients with GGE and left TLE after adjusting for learning capacity. We could not confirm the influence of epileptic activity on long\u2010term forgetting patterns. Future studies are required to better define domain\u2010specific differences in memory impairment in TLE and GGE.<\/jats:p><\/jats:sec>","DOI":"10.1002\/epi4.12779","type":"journal-article","created":{"date-parts":[[2023,6,29]],"date-time":"2023-06-29T07:04:57Z","timestamp":1688022297000},"page":"1279-1287","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Longer\u2010term verbal and visual memory patterns in patients with temporal lobe and genetic generalized epilepsies"],"prefix":"10.1002","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8527-3902","authenticated-orcid":false,"given":"Kristijonas","family":"Puteikis","sequence":"first","affiliation":[{"name":"Faculty of Medicine Vilnius University  Vilnius Lithuania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2547-976X","authenticated-orcid":false,"given":"Peter","family":"Wolf","sequence":"additional","affiliation":[{"name":"Center for Neurology Vilnius University  Vilnius Lithuania"},{"name":"Danish Epilepsy Center Filadelfia  Dianalund Denmark"},{"name":"Postgraduation Program of Medical Sciences Santa Catarina Federal University  Florian\u00f3polis Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5719-8175","authenticated-orcid":false,"given":"R\u016bta","family":"Mameni\u0161kien\u0117","sequence":"additional","affiliation":[{"name":"Center for Neurology Vilnius University  Vilnius Lithuania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,8,10]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.seizure.2020.10.009"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yebeh.2020.107027"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1017\/S1355617717000650"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2014.02.012"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jocn.2013.04.037"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropsychologia.2011.04.018"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/epi.12090"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/epi.17144"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yebeh.2020.106920"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cortex.2021.03.035"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.seizure.2011.10.007"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yebeh.2016.07.029"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cortex.2014.02.001"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1037\/0278-7393.11.1-4.817"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1037\/0278-7393.9.3.384"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1037\/0278-7393.11.1-4.812"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cortex.2018.04.005"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cortex.2017.12.012"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2022.104815"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cortex.2018.01.003"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cortex.2011.01.002"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cortex.2016.02.005"}],"container-title":["Epilepsia 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