{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T19:23:22Z","timestamp":1778873002107,"version":"3.51.4"},"reference-count":28,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2023,7,12]],"date-time":"2023-07-12T00:00:00Z","timestamp":1689120000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Epilepsia Open"],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Mesial temporal lobe epilepsy, one of the most common forms of epilepsy, is often linked with drug resistance. Surgical intervention is a reliable and safe treatment option, though research into postsurgical outcomes in our locality remains limited. We performed a retrospective observational study included 91 patients with mesial temporal lobe epilepsy and hippocampal sclerosis who had undergone anterior temporal lobectomy between 2012 and 2020 at a surgical epilepsy center located in Lima, Peru. Postoperative outcomes were analyzed using bivariate and multivariate analysis based on the Engel classification. We found that after 12\u2009months of follow\u2010up, 78.65% of the 91 patients achieved an Engel IA classification, while 9.09% attained Engel IB classification and 11.24% were designated as Engel II, with only 1.12% classified as Engel IVA. The median QOLIE31 score was 84 (IQR: 75\u201390), with 74.16% of the participants successfully reintegrating into academic or employment activities. After 24\u2009months, only 68 patients completed the follow\u2010up, with 69.12% achieving an Engel IA classification. Individuals with a secondary education or higher were more likely to achieve an Engel IA classification at 12\u2009months (OR: 5.11; <jats:italic>P<\/jats:italic>\u2009=\u20090.005; CI: 1.63\u201316.01), after adjusting for sex and age. We concluded that most patients exhibited favorable outcomes after 1\u2009year of follow\u2010up. However, lower educational attainment was linked to worse postsurgical outcomes.<\/jats:p>","DOI":"10.1002\/epi4.12784","type":"journal-article","created":{"date-parts":[[2023,7,3]],"date-time":"2023-07-03T07:14:05Z","timestamp":1688368445000},"page":"1175-1181","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Postsurgical outcomes in a cohort of patients with hippocampal sclerosis: Initial experience in a referral epilepsy center in Peru"],"prefix":"10.1002","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-1057-6129","authenticated-orcid":false,"given":"Walter F.","family":"De\u00a0La\u00a0Cruz\u00a0Ramirez","sequence":"first","affiliation":[{"name":"Epilepsy Department Instituto Nacional de Ciencias Neurol\u00f3gicas  Lima Per\u00fa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-2044-6183","authenticated-orcid":false,"given":"Denisse E.","family":"Chac\u00f3n\u00a0Zu\u00f1iga","sequence":"additional","affiliation":[{"name":"Epilepsy Department Instituto Nacional de Ciencias Neurol\u00f3gicas  Lima Per\u00fa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6101-1286","authenticated-orcid":false,"given":"Sof\u00eda S.","family":"S\u00e1nchez\u2010Boluarte","sequence":"additional","affiliation":[{"name":"Epilepsy Department Instituto Nacional de Ciencias Neurol\u00f3gicas  Lima Per\u00fa"},{"name":"School of Medicine Universidad Cesar Vallejo  Trujillo Per\u00fa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0394-3269","authenticated-orcid":false,"given":"Carlos M.","family":"V\u00e1squez\u00a0Perez","sequence":"additional","affiliation":[{"name":"Neurosurgery Department Instituto Nacional de Ciencias Neurol\u00f3gicas  Lima Per\u00fa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-6598-1780","authenticated-orcid":false,"given":"Liza N.","family":"Nu\u00f1ez\u00a0Del\u00a0Prado\u00a0Murillo","sequence":"additional","affiliation":[{"name":"Epilepsy Department Instituto Nacional de Ciencias Neurol\u00f3gicas  Lima Per\u00fa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6875-3397","authenticated-orcid":false,"given":"Jos\u00e9 C.","family":"Delgado\u00a0Rios","sequence":"additional","affiliation":[{"name":"Epilepsy Department Instituto Nacional de Ciencias Neurol\u00f3gicas  Lima 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