{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T08:32:52Z","timestamp":1791275572687,"version":"4.1.0"},"reference-count":31,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2013,2,7]],"date-time":"2013-02-07T00:00:00Z","timestamp":1360195200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Euro Eating Disorders Rev"],"published-print":{"date-parts":[[2013,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Anorexia nervosa (AN) is characterised by a refusal to normal body weight accompanied by a marked restriction of food intake, frequently leading to severe malnutrition. In severe malnutrition and wasting syndromes, mucosal atrophy, altered gastrointestinal motility and pancreatic atrophy, which alter digestive function and can exacerbate malnutrition, have been described. The objective of this work was to determine intestinal absorption and pancreatic function in severely malnourished AN patients before and after recovery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Ten severely malnourished AN women were studied at hospital admittance (body mass index\u2009=\u200911.44\u201316.16\u2009kg\/m<jats:sup>2<\/jats:sup>) and after weight recovery with artificial nutrition (body mass index\u2009\u2265\u200920\u2009kg\/m<jats:sup>2<\/jats:sup>). A <jats:sup>13<\/jats:sup>C\u2010labelled triglycerides digestion test, faecal elastase test and <jats:sc>d<\/jats:sc>\u2010xylose absorption test were performed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In nine patients, <jats:sup>13<\/jats:sup>C\u2010labelled triglycerides digestion tests and the faecal elastase and <jats:sc>d<\/jats:sc>\u2010xylose tests were normal both before and after weight recovery. In one patient, the results were abnormal, and they led to the detection of a previously undiagnosed celiac disease in addition to her AN.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In this series, there was neither intestinal absorption nor pancreatic function disturbances in severely malnourished AN patients either before or after weight recovery. The usefulness of these tests in the differentiation of functional versus structural changes needs further studies. Copyright \u00a9 2013 John Wiley &amp; Sons, Ltd and Eating Disorders Association.<\/jats:p><\/jats:sec>","DOI":"10.1002\/erv.2223","type":"journal-article","created":{"date-parts":[[2013,2,7]],"date-time":"2013-02-07T07:27:19Z","timestamp":1360222039000},"page":"247-251","source":"Crossref","is-referenced-by-count":19,"title":["Intestinal Absorption and Pancreatic Function are Preserved in Anorexia Nervosa Patients in Both a Severely Malnourished State and After Recovery"],"prefix":"10.1002","volume":"21","author":[{"given":"Miguel Angel","family":"Mart\u00ednez\u2010Olmos","sequence":"first","affiliation":[{"name":"Endocrinology and Nutrition Division Complejo Hospitalario Universitario de Santiago and Santiago de Compostela University  Spain"},{"name":"CIBERobn Instituto de Salud Carlos III  Santiago de Compostela Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto","family":"Pein\u00f3","sequence":"additional","affiliation":[{"name":"Endocrinology and Nutrition Division Complejo Hospitalario Universitario de Santiago and Santiago de Compostela University  Spain"},{"name":"CIBERobn Instituto de Salud Carlos III  Santiago de Compostela Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alma","family":"Prieto\u2010Tenreiro","sequence":"additional","affiliation":[{"name":"Endocrinology and Nutrition Division Complejo Hospitalario Universitario de Santiago and Santiago de Compostela University  Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary","family":"Lage","sequence":"additional","affiliation":[{"name":"Endocrinology and Nutrition Division Complejo Hospitalario Universitario de Santiago and Santiago de Compostela University  Spain"},{"name":"CIBERobn Instituto de Salud Carlos III  Santiago de Compostela Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Nieto","sequence":"additional","affiliation":[{"name":"Gastroenterology Division Complejo Hospitalario Universitario de Santiago and Santiago de Compostela University  Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teresa","family":"Lord","sequence":"additional","affiliation":[{"name":"Endocrinology and Nutrition Division Complejo Hospitalario Universitario de Santiago and Santiago de Compostela University  Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esther","family":"Molina\u2010P\u00e9rez","sequence":"additional","affiliation":[{"name":"Gastroenterology Division Complejo Hospitalario Universitario de Santiago and Santiago de Compostela University  Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan Enrique","family":"Dom\u00ednguez\u2010Mu\u00f1oz","sequence":"additional","affiliation":[{"name":"Gastroenterology Division Complejo Hospitalario Universitario de Santiago and Santiago de Compostela University  Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felipe F.","family":"Casanueva","sequence":"additional","affiliation":[{"name":"Endocrinology and Nutrition Division Complejo Hospitalario Universitario de Santiago and Santiago de Compostela University  Spain"},{"name":"CIBERobn Instituto de Salud Carlos III  Santiago de Compostela Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,2,7]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/00075197-200211000-00011"},{"key":"e_1_2_5_3_1","volume-title":"Diagnostic and Statistical Manual for Mental Disorders, Fourth Edition (DSM\u2010IV)","author":"American Psychiatric Association","year":"1994"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1177\/0148607195019005410"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.mco.0000247480.17829.34"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.29.03.06.dc05\u20101389"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1022849112100"},{"key":"e_1_2_5_8_1","first-page":"4","article-title":"Normal digestive physiology and the evaluation of digestive function","volume":"25","author":"Deutsch J. 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