{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T02:13:11Z","timestamp":1790734391747,"version":"4.1.0"},"reference-count":27,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2015,12,14]],"date-time":"2015-12-14T00:00:00Z","timestamp":1450051200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Euro Eating Disorders Rev"],"published-print":{"date-parts":[[2016,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Oxidative stress markers seem to be higher in patients with anorexia nervosa (AN) than healthy controls, but the potentially beneficial effects of weight gain is not known. We calculated random effects standardised mean differences (SMDs) as effect size measures of oxidative stress marker changes after re\u2010alimentation reported in two or more studies, summarising others descriptively. Seven longitudinal studies (<jats:italic>n<\/jats:italic>\u2009=\u2009104) were included. After a median follow\u2010up period of 8\u2009weeks, AN patients significantly increased their body mass index (15.1\u2009\u00b1\u20092.1 to 17.1\u2009\u00b1\u20092.2, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.0001). This weight gain was followed by a significant increase in serum levels of the antioxidant albumin (studies\u2009=\u20096, SMD\u2009=\u20090.50, 95%CI\u2009=\u20090.18; 0.82, <jats:italic>p<\/jats:italic>\u2009=\u20090.002; <jats:italic>I<\/jats:italic><jats:sup>2<\/jats:sup>\u2009=\u200916%) and a significant decrease in the oxidative stress marker Apolipoprotein B (studies\u2009=\u20092, <jats:italic>n<\/jats:italic>\u2009=\u200919, SMD\u2009=\u2009\u22120.85, 95%CI\u2009=\u2009\u22121.53; \u22120.17, <jats:italic>p<\/jats:italic>\u2009=\u20090.01; <jats:italic>I<\/jats:italic><jats:sup>2<\/jats:sup>\u2009=\u20090). In one study, catalase and total antioxidant capacity increased, whilst superoxide dismutase significantly decreased. In conclusion, oral re\u2010alimentation, even without full\u2010weight normalisation, seems to improve oxidative stress in people with AN. Copyright \u00a9 2015 John Wiley &amp; Sons, Ltd and Eating Disorders Association.<\/jats:p>","DOI":"10.1002\/erv.2420","type":"journal-article","created":{"date-parts":[[2015,12,14]],"date-time":"2015-12-14T11:11:58Z","timestamp":1450091518000},"page":"101-105","source":"Crossref","is-referenced-by-count":26,"title":["Oxidative Stress and Antioxidant Levels in Patients with Anorexia Nervosa after Oral Re\u2010alimentation: A Systematic Review and Exploratory Meta\u2010analysis"],"prefix":"10.1002","volume":"24","author":[{"given":"Marco","family":"Solmi","sequence":"first","affiliation":[{"name":"Department of Neurosciences University of Padova  Padova Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicola","family":"Veronese","sequence":"additional","affiliation":[{"name":"Department of Medicine\u2014DIMED, Geriatrics Section University of Padova  Padova Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudio","family":"Luchini","sequence":"additional","affiliation":[{"name":"Department of Pathology University of Verona  Verona Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enzo","family":"Manzato","sequence":"additional","affiliation":[{"name":"Department of Medicine\u2014DIMED, Geriatrics Section University of Padova  Padova Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Sergi","sequence":"additional","affiliation":[{"name":"Department of Medicine\u2014DIMED, Geriatrics Section University of Padova  Padova Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela","family":"Favaro","sequence":"additional","affiliation":[{"name":"Department of Neurosciences University of Padova  Padova Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo","family":"Santonastaso","sequence":"additional","affiliation":[{"name":"Department of Neurosciences University of Padova  Padova Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christoph U.","family":"Correll","sequence":"additional","affiliation":[{"name":"Department of Psychiatry The Zucker Hillside Hospital  Glen Oaks NY 11004 USA"},{"name":"Hofstra North Shore\u2010LIJ School of Medicine  Hempstead NY USA"},{"name":"The Feinstein Institute for Medical Research  Manhasset NY USA"},{"name":"Albert Einstein College of Medicine  Bronx NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,12,14]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1176\/ajp.139.12.1531"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1089\/jwh.2008.0988"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00394-009-0019-9"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.3109\/10715762.2013.772604"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/1743-7075-7-34"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/mp.2010.95"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0009-8981(99)00256-9"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2006.8.2187"},{"key":"e_1_2_7_10_1","first-page":"197","article-title":"Serum leptin levels in patients with anorexia nervosa before and after partial refeeding, relationships to serum lipids and biochemical nutritional parameters","volume":"48","author":"Haluz\u00edk M.","year":"1999","journal-title":"Physiol Res"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neures.2010.08.007"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncpcardio0500"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.4065\/mcp.2011.0128"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-244X-13-290"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2009.06.005"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1098-108X(199901)25:1<99::AID-EAT12>3.0.CO;2-N"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/eat.20298"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu7042193"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.febslet.2008.04.057"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/38.2.229"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/eat.22443"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1098-108X(199712)22:4<339::AID-EAT1>3.0.CO;2-N"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005053-198808000-00009"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2015.06.005"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/eat.22370"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463-1326.2007.00692.x"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ijo.0803177"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.0040296"}],"container-title":["European Eating Disorders Review"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Ferv.2420","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/erv.2420","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,6]],"date-time":"2023-10-06T01:23:46Z","timestamp":1696555426000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/erv.2420"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,12,14]]},"references-count":27,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2016,3]]}},"alternative-id":["10.1002\/erv.2420"],"URL":"https:\/\/doi.org\/10.1002\/erv.2420","archive":["Portico"],"relation":{},"ISSN":["1072-4133","1099-0968"],"issn-type":[{"value":"1072-4133","type":"print"},{"value":"1099-0968","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,12,14]]}}}