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Nine thousand three hundred two females with AN were compared to 92\u2009959 randomly selected age\u2010matched and practice\u2010matched females. Cox regression was used to estimate the hazard ratio (HR) for urolithiasis and evaluate effect modification by age. Twenty\u2010three participants with AN (0.25%) developed urolithiasis compared with 154 unexposed participants (0.17%) over a median of 4\u00a0years of observation. The risk of urolithiasis varied significantly with age (interaction <jats:italic>p<\/jats:italic>\u2009=\u20090.02). AN was associated with a more than threefold higher risk of urolithiasis in females \u226425\u00a0years of age (HR 3.49, 95% CI: 1.56\u20137.81; <jats:italic>p<\/jats:italic>\u2009=\u20090.002), but not in females over 25\u00a0years (HR 1.18, 95% CI: 0.69\u20132.02; <jats:italic>p<\/jats:italic>\u2009=\u20090.54). The distribution of diagnosis codes for urolithiasis differed between groups (<jats:italic>p<\/jats:italic>\u2009=\u20090.04), with a higher proportion of codes for uric acid urolithiasis in the AN (16.2%) <jats:italic>versus<\/jats:italic> unexposed group (5.0%). Copyright \u00a9 2017 John Wiley &amp; Sons, Ltd and Eating Disorders Association.<\/jats:p>","DOI":"10.1002\/erv.2526","type":"journal-article","created":{"date-parts":[[2017,6,29]],"date-time":"2017-06-29T06:56:39Z","timestamp":1498719399000},"page":"406-410","source":"Crossref","is-referenced-by-count":10,"title":["Risk of Urolithiasis in Anorexia Nervosa: A Population\u2010Based Cohort Study Using the Health Improvement Network"],"prefix":"10.1002","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0704-3607","authenticated-orcid":false,"given":"Michelle R.","family":"Denburg","sequence":"first","affiliation":[{"name":"The Children's Hospital of Philadelphia Perelman School of Medicine at the University of Pennsylvania  Philadelphia PA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mary B.","family":"Leonard","sequence":"additional","affiliation":[{"name":"Stanford University School of Medicine  Stanford CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas O.","family":"Jemielita","sequence":"additional","affiliation":[{"name":"Perelman School of Medicine at the University of Pennsylvania  Philadelphia PA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neville H.","family":"Golden","sequence":"additional","affiliation":[{"name":"Stanford University School of Medicine  Stanford CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gregory","family":"Tasian","sequence":"additional","affiliation":[{"name":"The Children's Hospital of Philadelphia Perelman School of Medicine at the University of Pennsylvania  Philadelphia PA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lawrence","family":"Copelovitch","sequence":"additional","affiliation":[{"name":"The Children's Hospital of Philadelphia Perelman School of Medicine at the University of Pennsylvania  Philadelphia PA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,6,29]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(05)81714-7"},{"issue":"8","key":"e_1_2_5_3_1","first-page":"433","article-title":"Renal disease and dysfunction in two patients with anorexia nervosa","volume":"47","author":"Brotman A. 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