{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T15:06:54Z","timestamp":1781795214711,"version":"3.54.5"},"reference-count":42,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2019,2,13]],"date-time":"2019-02-13T00:00:00Z","timestamp":1550016000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100012129","name":"Baker Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100012129","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004752","name":"State Government of Victoria","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004752","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001782","name":"University of Melbourne","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001782","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Euro Eating Disorders Rev"],"published-print":{"date-parts":[[2019,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Early response, as indicated by early weight gain, in family\u2010based treatment (FBT) for adolescent anorexia nervosa (AN) predicts remission at end of treatment. However, little is known about what factors contribute to early response. Further, no previous studies have examined early response to separated forms of FBT.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Data from a randomised clinical trial of conjoint FBT and separated FBT (parent\u2010focused treatment, PFT) were analysed to examine the timing and amount of early weight gain that predicted remission and identify factors associated with early response.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Weight gain of at least 2.80\u00a0kg in FBT (<jats:italic>N<\/jats:italic>\u00a0=\u00a055) and 2.28\u00a0kg in PFT (<jats:italic>N<\/jats:italic>\u00a0=\u00a051), by Session 5, were the best predictors of remission at end of treatment. Early response in FBT was predicted by greater paternal therapeutic alliance and lower paternal criticism. Early response in PFT was predicted by less severe eating\u2010disorder symptoms and negative affect at baseline, lower maternal criticism, and greater adolescent therapeutic alliance.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The results confirm that early weight gain is an important prognostic indicator in both conjoint FBT and PFT and suggest that addressing negative emotion, parental criticism, and therapeutic alliance early in treatment could improve remission rates.<\/jats:p><\/jats:sec>","DOI":"10.1002\/erv.2668","type":"journal-article","created":{"date-parts":[[2019,2,14]],"date-time":"2019-02-14T06:44:08Z","timestamp":1550126648000},"page":"283-294","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":55,"title":["Predictors of early response in conjoint and separated models of family\u2010based treatment for adolescent anorexia nervosa"],"prefix":"10.1002","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4377-5610","authenticated-orcid":false,"given":"Elizabeth K.","family":"Hughes","sequence":"first","affiliation":[{"name":"Department of Paediatrics University of Melbourne  Parkville Victoria Australia"},{"name":"Centre for Adolescent Health Murdoch Children's Research Institute  Parkville Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan M.","family":"Sawyer","sequence":"additional","affiliation":[{"name":"Department of Paediatrics University of Melbourne  Parkville Victoria Australia"},{"name":"Centre for Adolescent Health Murdoch Children's Research Institute  Parkville Victoria Australia"},{"name":"Department of Adolescent Medicine Royal Children's Hospital  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5521-6381","authenticated-orcid":false,"given":"Erin C.","family":"Accurso","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and UCSF Weill Institute for Neurosciences University of California, San Francisco  San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simar","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and UCSF Weill Institute for Neurosciences University of California, San Francisco  San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Le Grange","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and UCSF Weill Institute for Neurosciences University of California, San Francisco  San Francisco California USA"},{"name":"Department of Psychiatry and Behavioral Neuroscience The University of Chicago  Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,2,13]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/erv.2564"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.books.9780890423349"},{"key":"e_1_2_9_4_1","unstructured":"Centers for Disease Control and Prevention. 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