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The aim of this study was to empirically investigate Herpertz\u2010Dahlmann, Seitz, and Konrad (2011, https:\/\/doi.org\/10.1007\/s00406\u2010011\u20100246\u2010y)\u2019s developmental model and to consider if interpersonal reactions to the illness might serve as maintaining factors following the model proposed by Treasure and Schmidt (2013, https:\/\/doi.org\/10.1186\/2050\u20102974\u20101\u201013)<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>One hundred adolescents and their families were participated in the study: 50 diagnosed with AN, paired by age and parents\u2019 socio\u2010economic status with 50 adolescents without a pathology. Biological, psychological and familial variables were assessed using ten questionnaires and a blood analysis test. Additionally, structural equation modeling was conducted to assess two hypothetical models.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The fit of both models was good after the addition of two covariate parameters (e.g., Comparative Fit Index\u00a0&gt;\u00a00.96 and Tucker\u2013Lewis Index\u00a0&gt;\u00a00.95). Premorbid traits were linked to body dissatisfaction and to the number of stressful life events; this in turn was linked to AN symptoms. Biological and familial consequences reinforced this pathology.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Our findings provide support for both models, suggesting that inter relationships between bio\u2010psycho\u2010familial variables can influence the course of AN during adolescence.<\/jats:p><\/jats:sec>","DOI":"10.1002\/erv.2826","type":"journal-article","created":{"date-parts":[[2021,2,23]],"date-time":"2021-02-23T22:45:50Z","timestamp":1614120350000},"page":"548-558","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Adding maintaining factors to developmental models of anorexia nervosa: An empirical examination in adolescents"],"prefix":"10.1002","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6303-0915","authenticated-orcid":false,"given":"Alba","family":"Moreno\u2010Encinas","sequence":"first","affiliation":[{"name":"School of Psychology, Autonomous University of Madrid Biological and Health Psychology Department  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Montserrat","family":"Graell","sequence":"additional","affiliation":[{"name":"Child and Adolescent Psychiatry and Psychology Department University Hospital Ni\u00f1o Jes\u00fas CIBERSAM  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 \u00c1ngel","family":"Mart\u00ednez\u2010Huertas","sequence":"additional","affiliation":[{"name":"School of Psychology, Autonomous University of Madrid Cognitive Psychology Department  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar","family":"Faya","sequence":"additional","affiliation":[{"name":"Child and Adolescent Psychiatry and Psychology Department University Hospital Ni\u00f1o Jes\u00fas CIBERSAM  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janet","family":"Treasure","sequence":"additional","affiliation":[{"name":"Institute of Psychiatry, Psychology and Neuroscience King's College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6041-2889","authenticated-orcid":false,"given":"Ana Rosa","family":"Sep\u00falveda","sequence":"additional","affiliation":[{"name":"School of Psychology, Autonomous University of Madrid Biological and Health Psychology Department  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,2,23]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eatbeh.2014.06.001"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/erv.2440"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1586\/eog.12.54"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-7138(09)60602-6"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1080\/10640266.2018.1553431"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00702-012-0821-z"},{"key":"e_1_2_10_8_1","volume-title":"Structural equation modeling with Mplus: Basic Concepts, Applications, and Programming","author":"Byrne B.","year":"2011"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/1098-108X(198707)6:4<485::AID-EAT2260060405>3.0.CO;2-O"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpp.12441"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00737-017-0761-6"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1177\/001316447803800404"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.comppsych.2013.10.002"},{"issue":"3","key":"e_1_2_10_14_1","first-page":"1","article-title":"A 57\u2010year follow\u2010Up investigation and review of the Minnesota study on Human starvation and its relevance to eating disorders","volume":"2","author":"Eckert E. 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