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Family\u2010based treatment (FBT) has never been compared to long inpatient, multimodal treatment (IMT) in a randomized controlled trial (RCT). The aim of this study was to compare data on body weight trajectories, change in eating disorder psychopathology, hospital days and treatment costs in RCTs delivering FBT or IMT.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Review of RCTs published between 2010 and 2020 in youth with AN, delivering FBT or IMT.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Four RCTs delivering FBT (United States, <jats:italic>n<\/jats:italic>\u00a0=\u00a02; Australia, <jats:italic>n<\/jats:italic>\u00a0=\u00a02), one RCT delivering Family Therapy for AN (United Kingdom) and two RCTs delivering IMT (France, <jats:italic>n<\/jats:italic>\u00a0=\u00a01; Germany, <jats:italic>n<\/jats:italic>\u00a0=\u00a01) were identified from previous meta\u2010analyses. The comparison of studies was limited by (1) significant differences in patient baseline characteristics including pretreated versus non\u2010pretreated patients, (2) use of different psychometric and weight measures and (3) different initial velocity of weight recovery. Minimal baseline and outcome reporting standards for body weight metrics and\u00a0nature\/dose of interventions allowing international comparison are needed and suggestions to developing these standards are presented.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>An RCT should investigate, whether FBT is a viable alternative to IMT, leading to comparable weight and psychopathology improvement with less inpatient time and costs.<\/jats:p><\/jats:sec>","DOI":"10.1002\/erv.2907","type":"journal-article","created":{"date-parts":[[2022,4,27]],"date-time":"2022-04-27T03:49:52Z","timestamp":1651031392000},"page":"693-705","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Comparing randomized controlled trials of outpatient family\u2010based or inpatient multimodal treatment followed by outpatient care in youth with anorexia nervosa: Differences in populations, metrics, and outcomes"],"prefix":"10.1002","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8841-2381","authenticated-orcid":false,"given":"Verena","family":"Haas","sequence":"first","affiliation":[{"name":"Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin Corporate Member of Freie Universit\u00e4t Berlin and Humboldt Universit\u00e4t zu Berlin  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janine","family":"Nadler","sequence":"additional","affiliation":[{"name":"Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin Corporate Member of Freie Universit\u00e4t Berlin and Humboldt Universit\u00e4t zu Berlin  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ross D.","family":"Crosby","sequence":"additional","affiliation":[{"name":"Sanford Center for Biobehavioral Research University of North Dakota School of Medicine and Health Sciences  Fargo North Dakota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sloane","family":"Madden","sequence":"additional","affiliation":[{"name":"University of Sydney  Sydney Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Kohn","sequence":"additional","affiliation":[{"name":"Department of Adolescent and Young Adult Medicine Centre for Research into Adolescent\u2019S Health Westmead Hospital University of Sydney  Sydney Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Le Grange","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Behavioral Sciences University of California  San Francisco California USA"},{"name":"Department of Psychiatry and Behavioral Neuroscience The University of Chicago  Chicago IL USA (Emeritus)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Sofia Oliveira","family":"Gon\u00e7alves","sequence":"additional","affiliation":[{"name":"Institute of Public Health Charit\u00e9 \u2010 Universit\u00e4tsmedizin Humboldt\u2010Universit\u00e4t zu Berlin, and Berlin Institute of Health  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johannes","family":"Hebebrand","sequence":"additional","affiliation":[{"name":"Department of Child and Adolescent Psychiatry, Psychotherapy and Psychosomatics University Hospital Essen University of Duisburg\u2010Essen  Essen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christoph U.","family":"Correll","sequence":"additional","affiliation":[{"name":"Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin Corporate Member of Freie Universit\u00e4t Berlin and Humboldt Universit\u00e4t zu Berlin  Berlin Germany"},{"name":"Donald and Barbara Zucker School of Medicine at Hofstra\/Northwell  Hempstead New York USA"},{"name":"Department of Psychiatry The Zucker Hillside Hospital  Glen Oaks New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,4,26]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brat.2014.02.006"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamapsychiatry.2014.1025"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1080\/09540261.2019.1588711"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1590\/S1679-45082016RW3120"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40337-020-0277-8"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/eat.22042"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12888-016-1129-6"},{"key":"e_1_2_10_9_1","first-page":"CD004780","article-title":"Family therapy approaches for anorexia nervosa","volume":"5","author":"Fisher C. 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