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However, publications reported conflicting results on the directionality and location of the abnormal activations. There is an urgent need to integrate our existing knowledge of anticipation, both rewarding and aversive, to elucidate these differences.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>We conducted an activation likelihood estimation (ALE) meta\u2010analysis to quantitatively review functional neuroimaging studies that evaluated differences between brain correlates of anticipation in participants with and without disordered eating. PubMed, Web of Sciences, PsycINFO, Medline and EMBASE were searched for studies published up to November 2022. Exploratory sub\u2010analyses to check for differences between reward and non\u2010reward anticipation among all anticipation paradigms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Twenty\u2010one references met the inclusion criteria for meta\u2010analysis. The meta\u2010analysis across anticipation all tasks identified a significant hyperactivation cluster in the right putamen in participants with disordered eating (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a017 experiments) and a significant hypoactivation cluster in the left inferior parietal lobule (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a013 experiments), in participants with disordered eating compared to controls.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>These findings and sub\u2010analyses of reward\u2010 and non\u2010reward\u2010related cues suggest potential pathophysiological mechanisms underlying anticipatory responses to rewarding and aversive cues in ED.<\/jats:p>\n                  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