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However, the psychological mediators of this association have received scant attention in the literature.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>The present study aimed to evaluate the mediating role of psychological maladjustment, alexithymia, and self\u2010esteem in the relationship between sexual abuse and EDs severity in a sample of 134 treatment\u2010na\u00efve patients with an EDs and 129 paired healthy controls.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In the EDs group, EDs severity among participants who had been sexually abused was mediated by greater psychological maladjustment and alexithymia (indirect effects: <jats:italic>\u03b2<\/jats:italic>\u00a0=\u00a012.55, 95% CI [6.11\u201319.87] <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.001; <jats:italic>\u03b2<\/jats:italic>\u00a0=\u00a03.22, 95% CI [0.235\u20137.97] <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.05, respectively). By contrast, these variables had no significant mediating effect on EDs severity in the control group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>These findings support the hypothesis of a disorder\u2010related relationship between sexual abuse and alexithymia and psychological maladjustment, which, in turn, influences EDs severity. Alexithymia and psychological maladjustment appear to be promising therapeutic targets for patients with EDs who have a history of sexual abuse.<\/jats:p><\/jats:sec>","DOI":"10.1002\/erv.2991","type":"journal-article","created":{"date-parts":[[2023,6,8]],"date-time":"2023-06-08T04:22:21Z","timestamp":1686198141000},"page":"629-642","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Mediators between sexual abuse and eating disorder severity: A comparative case\u2010control study in treatment\u2010na\u00efve patients"],"prefix":"10.1002","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6862-5635","authenticated-orcid":false,"given":"Ludovica","family":"Ventura","sequence":"first","affiliation":[{"name":"Valdecilla Biomedical Research Institute (IDIVAL)  Santander Spain"},{"name":"Faculty of Medicine and Mental Health University of Cantabria  Santander Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andr\u00e9s","family":"G\u00f3mez del Barrio","sequence":"additional","affiliation":[{"name":"Valdecilla Biomedical Research Institute (IDIVAL)  Santander Spain"},{"name":"Eating Disorders Unit Department of Psychiatry Marqu\u00e9s de Valdecilla University Hospital  Santander Spain"},{"name":"Biomedical Research Centre of Mental Health (CIBERSAM) ISCIII  Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda","family":"Miras\u2010Aguilar","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Marqu\u00e9s de Valdecilla University Hospital  Santander Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9","family":"Ruiz\u2010Guti\u00e9rrez","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Marqu\u00e9s de Valdecilla University Hospital  Santander Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jana","family":"Gonz\u00e1lez G\u00f3mez","sequence":"additional","affiliation":[{"name":"Valdecilla Biomedical Research Institute (IDIVAL)  Santander Spain"},{"name":"Eating Disorders Unit Department of Psychiatry Marqu\u00e9s de Valdecilla University Hospital  Santander Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C\u00e9sar","family":"Gonz\u00e1lez\u2010Blanch","sequence":"additional","affiliation":[{"name":"Mental Health Centre Marqu\u00e9s de Valdecilla University Hospital \u2010 IDIVAL  Santander Spain"},{"name":"Faculty of Health Sciences Universidad Europea del Atl\u00e1ntico  Santander Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,6,7]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0954579419001317"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0145\u20102134(01)00238\u20101"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1177\/070674371205701105"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1503\/cmaj.131792"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022\u20103999(94)90006\u2010x"},{"issue":"3","key":"e_1_2_10_7_1","first-page":"399","article-title":"Predictors of eating disorder risk in anorexia nervosa adolescents","volume":"57","author":"Batista M.","year":"2018","journal-title":"Acta Clinica Croatica"},{"key":"e_1_2_10_8_1","first-page":"149","volume-title":"Eating disorders: Prevalence, risk factors and treatment options. 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