{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T21:37:23Z","timestamp":1790199443640,"version":"4.1.0"},"reference-count":48,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2023,10,29]],"date-time":"2023-10-29T00:00:00Z","timestamp":1698537600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Euro Eating Disorders Rev"],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>This prospective, longitudinal study aims to compare the prevalence of autism spectrum disorder (ASD) characteristics in adolescents with anorexia nervosa (AN) during and after underweight in order to help unravel the complex link between both conditions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>24 adolescents with AN completed the youth self\u2010report, autism spectrum quotient (AQ) or autism spectrum quotient adolescent version (AQ \u2013 adolescent) and a questionnaire designed by the researchers during a state of underweight and after weight recovery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>AQ total score and several AQ subscale scores at the time of underweight are significantly higher than after weight recovery with medium to large effect sizes. Linear modelling cannot prove a significant effect of weight gain, internalizing problems or medication use on AQ score, but it does show an association between AQ during underweight and AQ after weight recovery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The results highlight the complexity of the link between AN and ASD characteristics. Although a clear change in AQ score is seen in part of the participants, this effect cannot be generalized and a link with weight change cannot be demonstrated. It seems likely that ASD characteristics in AN are a combination of trait and state: underweight and starvation might exacerbate potentially present traits. Part of our results may indicate the existence of subgroups based on AQ score during underweight. Our study supports the theory that more ASD characteristics at T1 may result in a poorer outcome and a higher need for specified and intensive treatment.<\/jats:p><\/jats:sec>","DOI":"10.1002\/erv.3042","type":"journal-article","created":{"date-parts":[[2023,10,29]],"date-time":"2023-10-29T17:43:46Z","timestamp":1698601426000},"page":"310-321","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["A longitudinal study of autism spectrum disorder characteristics in adolescents with restrictive type anorexia nervosa during and after underweight"],"prefix":"10.1002","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-0456-0930","authenticated-orcid":false,"given":"Marieke","family":"Nuyttens","sequence":"first","affiliation":[{"name":"Ghent University Faculty of Medicine and Health Sciences  Ghent Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annik","family":"Simons","sequence":"additional","affiliation":[{"name":"Department for Child and Adolescent Psychiatry Antwerp University Hospital  Antwerp Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Inge","family":"Antrop","sequence":"additional","affiliation":[{"name":"Ghent University Faculty of Medicine and Health Sciences  Ghent Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Inge","family":"Glazemakers","sequence":"additional","affiliation":[{"name":"Antwerp University Faculty of Medicine and Health Sciences  Antwerp Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,10,29]]},"reference":[{"key":"e_1_2_9_2_1","volume-title":"Manual for the ASEBA school\u2010age forms & profiles","author":"Achenbach T. 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