{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T14:58:30Z","timestamp":1787237910953,"version":"build-2736575974"},"reference-count":62,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2023,11,27]],"date-time":"2023-11-27T00:00:00Z","timestamp":1701043200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Euro Eating Disorders Rev"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>\n                      Multi\u2010family therapy for anorexia nervosa (MFT\u2010AN) is a novel, group\u2010based intervention that intensifies single\u2010family therapy for anorexia nervosa (FT\u2010AN), with the aim of improving outcomes. The current study explored treatment moderators in a randomised controlled trial (\n                      <jats:italic>N<\/jats:italic>\n                      \u00a0=\u00a0167) of FT\u2010AN and MFT\u2010AN for young people (adolescents\/emerging adults aged 13\u201320\u00a0years) with anorexia nervosa.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Data were analysed using multiple linear regression. Six hypothesised baseline participant and parent factors were tested as possible moderators of treatment effect on end\u2010of\u2010treatment and follow\u2010up percentage of median Body Mass Index (%mBMI); age, eating disorder symptom severity, perceived family conflict (young person and parent ratings) and parent\u2010rated experiences of caregiving (positive and negative).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Greater parent\u2010rated positive caregiving experiences moderated treatment outcomes at follow\u2010up (\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u00a0=\u00a0\u22120.47, 95%CI: \u22120.91, \u22120.03,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.04), but not end\u2010of\u2010treatment. Participants who had fewer parent\u2010rated positive caregiving experiences at baseline had higher weight at follow\u2010up if they had MFT\u2010AN compared to FT\u2010AN. No other hypothesised baseline factors moderated treatment outcome (\n                      <jats:italic>p<\/jats:italic>\n                      's\u00a0&gt;\u00a00.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>The current study suggests MFT\u2010AN may be indicated for families who present with fewer positive caregiving experiences to treatment. The MFT\u2010AN group context may help to promote mentalisation and hope for these families, which may be harder to achieve in single\u2010family treatment. Future research is needed to empirically evaluate how and why MFT\u2010AN supports this group more.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial Registration<\/jats:title>\n                    <jats:p>ISRCTN registry: ISRCTN11275465, registered 29 January 2007.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/erv.3050","type":"journal-article","created":{"date-parts":[[2023,11,27]],"date-time":"2023-11-27T18:58:33Z","timestamp":1701111513000},"page":"17-28","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Moderators of treatment effect in a randomised controlled trial of single\u2010 and multi\u2010family therapy for anorexia nervosa in adolescents and emerging adults"],"prefix":"10.1002","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7840-4158","authenticated-orcid":false,"given":"Julian","family":"Baudinet","sequence":"first","affiliation":[{"name":"Centre for Research in Eating and Weight Disorders Institute of Psychiatry, Psychology and Neuroscience King's College London  London UK"},{"name":"Maudsley Centre for Child and Adolescent Eating Disorders South London and Maudsley NHS Foundation Trust  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7546-9901","authenticated-orcid":false,"given":"John","family":"Hodsoll","sequence":"additional","affiliation":[{"name":"Department of Biostatistics and Health Informatics School of Mental Health and Psychological Sciences Institute of Psychiatry, Psychology and Neuroscience King's College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1335-1937","authenticated-orcid":false,"given":"Ulrike","family":"Schmidt","sequence":"additional","affiliation":[{"name":"Centre for Research in Eating and Weight Disorders Institute of Psychiatry, Psychology and Neuroscience King's College London  London UK"},{"name":"Adult Eating Disorders Service South London and Maudsley NHS Foundation Trust  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4900-1429","authenticated-orcid":false,"given":"Mima","family":"Simic","sequence":"additional","affiliation":[{"name":"Maudsley Centre for Child and Adolescent Eating Disorders South London and Maudsley NHS Foundation Trust  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3615-8075","authenticated-orcid":false,"given":"Sabine","family":"Landau","sequence":"additional","affiliation":[{"name":"Department of Biostatistics and Health Informatics School of Mental Health and Psychological Sciences Institute of Psychiatry, Psychology and Neuroscience King's College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8211-7514","authenticated-orcid":false,"given":"Ivan","family":"Eisler","sequence":"additional","affiliation":[{"name":"Centre for Research in Eating and Weight Disorders Institute of Psychiatry, Psychology and Neuroscience King's College London  London UK"},{"name":"Maudsley Centre for Child and Adolescent Eating Disorders South London and Maudsley NHS Foundation Trust  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,11,27]]},"reference":[{"key":"e_1_2_10_2_1","volume-title":"Diagnostic and statistical manual of mental disorders: DSM\u2010IV","author":"American Psychiatric Association","year":"1994"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/EAT.23616"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/erv.3006"},{"key":"e_1_2_10_5_1","unstructured":"Baudinet J. 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