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Lifetime history of all fractures, including stress fractures, was higher in AN groups (FE\u2010AN\u00a0=\u00a033.3%; P\u2010AN\u00a0=\u00a037.8%) than in HC (4.2%, <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.001). P\u2010AN participants were 13.4 times more likely to report a fracture compared to HC, irrespective of age, whereas F\u2010AN participants were 10.3 times more likely. In P\u2010AN, higher BMI, shorter duration of amenorrhoea and history of pregnancy were inversely associated with fracture number.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>There is an increased risk of bone fracture even in the early stages of AN. This could be related to a time lapse between the initial symptoms of AN and formal diagnosis. This suggests guidelines recommending bone screening after 2\u2010years of persistent low weight for adults should be revisited, and the risk of bone problems should be part of the dialogue between clinicians, patients and carers at the earliest opportunity.<\/jats:p><\/jats:sec>","DOI":"10.1002\/erv.3153","type":"journal-article","created":{"date-parts":[[2024,11,22]],"date-time":"2024-11-22T03:59:18Z","timestamp":1732247958000},"page":"447-459","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Bone Fracture History in Women With First Episode or With Persistent Anorexia Nervosa"],"prefix":"10.1002","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3481-3897","authenticated-orcid":false,"given":"Mariana P.","family":"Lopes","sequence":"first","affiliation":[{"name":"Department of Psychological Medicine Centre for Research in Eating and Weight Disorders Institute of Psychiatry, Psychology &amp; Neuroscience King's College London  London UK"},{"name":"Nutrition Department School of Public Health University of S\u00e3o Paulo  S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sana","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Social, Genetic and Developmental Psychiatry (SGDP) Centre Institute of Psychiatry Psychology &amp; Neuroscience King's College London  London UK"},{"name":"Syed Babar Ali School of Science and Engineering Lahore University of Management Sciences  Lahore Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lily","family":"Beaman","sequence":"additional","affiliation":[{"name":"Psychology and Neuroscience Institute of Psychiatry Kings College London  London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brendon","family":"Stubbs","sequence":"additional","affiliation":[{"name":"Centre for Sport Science and University Sports University of Vienna  Vienna Austria"},{"name":"Department of Psychological Medicine Institute of Psychiatry, Psychology and Neuroscience King's College London  London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iain C.","family":"Campbell","sequence":"additional","affiliation":[{"name":"Department of Psychological Medicine Centre for Research in Eating and Weight Disorders Institute of Psychiatry, Psychology &amp; Neuroscience King's College London  London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulrike","family":"Schmidt","sequence":"additional","affiliation":[{"name":"Department of Psychological Medicine Centre for Research in Eating and Weight Disorders Institute of Psychiatry, Psychology &amp; Neuroscience King's College London  London UK"},{"name":"Eating Disorders Outpatient Unit South London and Maudsley NHS Foundation Trust  London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lauren","family":"Robinson","sequence":"additional","affiliation":[{"name":"Department of Psychological Medicine Centre for Research in Eating and Weight Disorders Institute of Psychiatry, Psychology &amp; Neuroscience King's College London  London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,11,21]]},"reference":[{"key":"e_1_2_11_2_1","unstructured":"ALSPAC Executive Committee. n.d. \u201cAvon Longitudinal Study of Parents and Children Questionnaires.\u201dhttp:\/\/www.bristol.ac.uk\/alspac\/researchers\/our\u2010data\/questionnaires\/."},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00198\u2010022\u201006312\u20102"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.2697"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.15288\/jsa.1995.56.423"},{"key":"e_1_2_11_6_1","volume-title":"Life Events and Illness","author":"Brown G. 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