{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T02:01:12Z","timestamp":1776909672472,"version":"3.51.2"},"reference-count":70,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,8,6]],"date-time":"2025-08-06T00:00:00Z","timestamp":1754438400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Euro Eating Disorders Rev"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>At a phenotypical level, the repeated occurrence of binge eating episodes clearly differentiates individuals with binge eating disorder (BED) from individuals with overweight but without BED. Their neural profiles during food\u2010related inhibition, however, indicate prefrontal hypoactivation in both groups. The present study investigated differential neural activations in upper lateral (right dorsolateral prefrontal cortex [DLPFC]) and inferior (right inferior frontal gyrus [IFG]) control regions during food\u2010related inhibition by functional near\u2010infrared spectroscopy (fNIRS). In addition, activity in reward\u2010related brain regions (orbitofrontal cortex [OFC]) during stimulus processing was measured.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>\n                      Individuals with BED (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a032), a control group of individuals with overweight and without BED (OWC,\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a021), and a control group of individuals with normal weight and without BED (NWC;\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a031) underwent a Go\/No\u2010Go (GNG) and a stimulus degradation task during fNIRS, both with food and non\u2010food stimuli in counterbalanced order.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Most predicted outcomes were not significant. Neural recordings during GNG underscore prefrontal hypoactivation in both BED and OWC relative to NWC, however, with differential alterations: In the Food\u2010NoGo condition, the BED group displayed hypoactivation in the IFG, while the OWC showed hypoactivation in the DLPFC.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The results suggest differential requirements for DLPFC and IFG recruitment during food\u2010related inhibition in individuals with BED and overweight.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/erv.70020","type":"journal-article","created":{"date-parts":[[2025,8,7]],"date-time":"2025-08-07T06:29:30Z","timestamp":1754548170000},"page":"202-212","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Prefrontal Cortex Recruitment to Food Stimuli Differs in Overweight\/Obesity and 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T\u00fcbingen Germany"},{"name":"German Center of Mental Health (DZPG)  T\u00fcbingen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dustin","family":"Werle","sequence":"additional","affiliation":[{"name":"Department of Clinical Psychology and Psychotherapy University of Tuebingen T\u00fcbingen Center of Mental Health (T\u00fcCMH)  T\u00fcbingen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ann\u2010Christine","family":"Ehlis","sequence":"additional","affiliation":[{"name":"German Center of Mental Health (DZPG)  T\u00fcbingen Germany"},{"name":"Department of Psychiatry and Psychotherapy University of Tuebingen T\u00fcbingen Center of Mental Health (T\u00fcCMH)  T\u00fcbingen 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