{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,3]],"date-time":"2026-04-03T20:50:09Z","timestamp":1775249409001,"version":"3.50.1"},"reference-count":50,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,12,25]],"date-time":"2025-12-25T00:00:00Z","timestamp":1766620800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,12,25]],"date-time":"2025-12-25T00:00:00Z","timestamp":1766620800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Euro Eating Disorders Rev"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>While high caloric realimentation (HCR) is increasingly recommended for quick weight restoration of patients with anorexia nervosa (AN), the development of AN\u2010specific psychopathology and somatic symptoms during HCR have so far insufficiently been studied.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>Patients hospitalised for the treatment of AN received oral realimentation starting with 2000\u00a0kcal under close medical monitoring and a substitution regimen. Weekly over the initial 6\u00a0weeks of treatment, assessments included body weight, drive for thinnesss, body dissatisfaction, depression, and somatic symptoms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      In 46 patients (mean age 27.57\u00a0years, 2 males, 44 females), the body mass index increased from 12.6 (SD 1.1) at baseline to 14.4 (SD 1.0) kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.001) at week 6 (\n                      <jats:italic>d<\/jats:italic>\n                      \u00a0=\u00a02.57). Drive for thinnesss did not change (28.9 [SD 10.2] to 27.7 [SD 10.8];\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.102), while body dissatisfaction increased slightly from 37.3 (SD 7.8) to 39.1 (SD 9.2;\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.019;\n                      <jats:italic>d<\/jats:italic>\n                      \u00a0=\u00a00.41). Depression and somatic symptoms decreased significantly (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.001) with large effect sizes (\n                      <jats:italic>d<\/jats:italic>\n                      \u00a0=\u00a01.09,\n                      <jats:italic>d<\/jats:italic>\n                      \u00a0=\u00a00.90, respectively). No case of refeeding syndrome was encountered.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>HCR was medically safe and associated with a decrease in depressive and somatic symptoms at only slight increase in body dissatisfaction. Fast realimentation brings patients with extreme AN quickly out of a weight range dangerous to their health.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/erv.70074","type":"journal-article","created":{"date-parts":[[2025,12,26]],"date-time":"2025-12-26T07:49:52Z","timestamp":1766735392000},"page":"835-844","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["High\u2010Caloric Realimentation and Mental and Physical Well\u2010Being in Patients With Extreme Anorexia Nervosa. A Prospective Study"],"prefix":"10.1002","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0261-3145","authenticated-orcid":false,"given":"Ulrich","family":"Voderholzer","sequence":"first","affiliation":[{"name":"Department of Psychiatry and Psychotherapy University Hospital Ludwig\u2010Maximilians\u2010University (LMU)  Munich Germany"},{"name":"Schoen Clinic Roseneck  Prien Germany"},{"name":"Department of Psychiatry and Psychotherapy University Hospital of Freiburg  Freiburg im Breisgau Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juliane","family":"Silbernagl","sequence":"additional","affiliation":[{"name":"Schoen Clinic Roseneck  Prien Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8841-2381","authenticated-orcid":false,"given":"Verena","family":"Haas","sequence":"additional","affiliation":[{"name":"Department of Child and Adolescent Psychiatry Charit\u00e9\u2010Universit\u00e4tsmedizin Berlin  Berlin Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2394-9935","authenticated-orcid":false,"given":"Ulrich","family":"Cuntz","sequence":"additional","affiliation":[{"name":"Schoen Clinic Roseneck  Prien Germany"},{"name":"Paracelsus Medical University  Salzburg Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9084-196X","authenticated-orcid":false,"given":"Silke","family":"Naab","sequence":"additional","affiliation":[{"name":"Schoen Clinic Roseneck  Prien Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6252-3315","authenticated-orcid":false,"given":"Norbert","family":"Quadflieg","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Psychotherapy University Hospital Ludwig\u2010Maximilians\u2010University (LMU)  Munich Germany"},{"name":"Schoen Clinic Roseneck  Prien Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,12,25]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/eat.23931"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1080\/10640266.2021.1939920"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1176\/ajp.152.7.1070"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psym.2020.06.020"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0192761"},{"key":"e_1_2_11_7_1","volume-title":"Statistical Power Analysis for the Behavioral Sciences","author":"Cohen J.","year":"1988"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/erv.2877"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm11092585"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnesp.2016.09.005"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1207\/s15327752jpa4901_13"},{"key":"e_1_2_11_12_1","volume-title":"BSI \u2010 Brief Symptom Inventory Von Derogatis (Kurzform Der SCL\u201090\u2010R) \u2010 Deutsche Version","author":"Franke G. 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