{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T14:03:36Z","timestamp":1784815416307,"version":"3.55.0"},"reference-count":52,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2017,5,1]],"date-time":"2017-05-01T00:00:00Z","timestamp":1493596800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"},{"start":{"date-parts":[[2017,3,2]],"date-time":"2017-03-02T00:00:00Z","timestamp":1488412800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100000041","name":"Fisheries and Oceans Canada","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000041","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000041","name":"Fisheries and Oceans Canada","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000041","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["setac.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2017,5,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>\u2003<\/jats:title>\n                  <jats:p>The effects of 2 currently used commercial pesticide formulations on Pacific sockeye salmon (Oncorhynchus nerka), from fertilization to emergence, were evaluated in a gravel-bed flume incubator that simulated a natural streambed. Embryos were exposed to atrazine at 25\u2009\u00b5g\/L (low atrazine) or atrazine at 250\u2009\u00b5g\/L (high atrazine) active ingredient (a.i.), and chlorothalonil at 0.5\u2009\u00b5g\/L (low chlorothalonil) or chlorothalonil at 5\u2009\u00b5g\/L a.i. (high chlorothalonil) and examined for effects on developmental success and timing, as well as physical and biochemical growth parameters. Survival to hatch was reduced in the high chlorothalonil group (55% compared with 83% in controls), accompanied by a 24% increase in finfold deformity incidence. Reduced alevin condition factor (2.9\u20135.4%) at emergence and elevated triglyceride levels were seen in chlorothalonil-exposed fish. Atrazine exposure caused premature hatch (average high atrazine time to 50% hatch [H50]\u2009=\u2009100\u2009d postfertilization [dpf]), and chlorothalonil exposure caused delayed hatch (high chlorothalonil H50\u2009=\u2009108 dpf; controls H50\u2009=\u2009102\u2009dpf). All treatments caused premature emergence (average time to 50% emergence [E50]: control E50\u2009=\u2009181\u2009dpf, low chlorothalonil E50\u2009=\u2009175\u2009dpf, high chlorothalonil E50\u2009=\u2009174\u2009dpf, high atrazine E50\u2009=\u2009175\u2009dpf, low atrazine E50\u2009=\u2009174\u2009dpf), highlighting the importance of using a gravel-bed incubator to examine this subtle, but critical endpoint. These alterations indicate that atrazine and chlorothalonil could affect survival of early life stages of sockeye salmon in the wild. Environ Toxicol Chem 2017;36:1354\u20131364. \u00a9 2017 SETAC<\/jats:p>\n               <\/jats:sec>","DOI":"10.1002\/etc.3753","type":"journal-article","created":{"date-parts":[[2017,3,2]],"date-time":"2017-03-02T13:56:46Z","timestamp":1488463006000},"page":"1354-1364","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":38,"title":["Effects of atrazine and chlorothalonil on the reproductive success, development, and growth of early life stage sockeye salmon (<i>Oncorhynchus nerka<\/i>)"],"prefix":"10.1093","volume":"36","author":[{"given":"Lindsay M.","family":"Du Gas","sequence":"first","affiliation":[{"name":"Department of Biological SciencesSimon Fraser University Burnaby British Columbia Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter S.","family":"Ross","sequence":"additional","affiliation":[{"name":"Ocean Pollution Science ProgramVancouver Aquarium Marine Science Center Vancouver British 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