{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T01:31:15Z","timestamp":1780623075014,"version":"3.54.1"},"reference-count":58,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2020,2,11]],"date-time":"2020-02-11T00:00:00Z","timestamp":1581379200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"},{"start":{"date-parts":[[2020,3,22]],"date-time":"2020-03-22T00:00:00Z","timestamp":1584835200000},"content-version":"vor","delay-in-days":40,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100023431","name":"Northern Contaminants Program","doi-asserted-by":"crossref","award":["Project M-10"],"award-info":[{"award-number":["Project M-10"]}],"id":[{"id":"10.13039\/100023431","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100023431","name":"Northern Contaminants Program","doi-asserted-by":"crossref","award":["Project M-16"],"award-info":[{"award-number":["Project M-16"]}],"id":[{"id":"10.13039\/100023431","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Institutional Development Award (IDeA) from the National Institute of General Medical Sciences of the National Institutes of Health","award":["2P20GM103395"],"award-info":[{"award-number":["2P20GM103395"]}]}],"content-domain":{"domain":["setac.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2020,2,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Dried blood spots (DBS), created by applying and drying a whole blood sample onto filter paper, provide a simple and minimally invasive procedure for collecting, transporting, and storing blood. Because DBS are ideal for use in field and resource-limited settings, we aimed to develop a simple and accurate DBS-based approach for assessing mercury (Hg) exposure and dietary carbon sources for landlocked Arctic char, a sentinel fish species in the Arctic. We collected liquid whole blood (from the caudal vein), muscle, liver, and brains of Arctic char (n\u2009=\u200936) from 8 lakes spanning a Hg gradient in the Canadian High Arctic. We measured total Hg concentrations ([THg]) of field-prepared DBS and Arctic char tissues. Across a considerable range, [THg] of DBS (0.04\u20133.38\u2009\u03bcg\/g wet wt) were highly correlated with [THg] of all tissues (r2 range\u2009=\u20090.928\u20130.996). We also analyzed the compound-specific carbon isotope ratios (expressed as \u03b413C values) of essential amino acids (EAAs) isolated from DBS, liquid whole blood, and muscle. The \u03b413C values of 5 EAAs (\u03b413CEAAs; isoleucine [Ile], leucine [Leu], phenylalanine [Phe], valine [Val], and threonine [Thr]) from DBS were highly correlated with \u03b413CEAAs of liquid whole blood (r2 range\u2009=\u20090.693\u20130.895) and muscle (r2 range\u2009=\u20090.642\u20130.881). The patterns of \u03b413CEAAs of landlocked Arctic char were remarkably consistent across sample types and indicate that EAAs are most likely of algal origin. Because a small volume of blood (~50\u2009\u00b5L) dried on filter paper can be used to determine Hg exposure levels of various tissues and to fingerprint carbon sources, DBS sampling may decrease the burdens of research and may be developed as a nonlethal sampling technique. Environ Toxicol Chem 2020;39:893\u2013903. \u00a9 2020 SETAC<\/jats:p>","DOI":"10.1002\/etc.4686","type":"journal-article","created":{"date-parts":[[2020,2,12]],"date-time":"2020-02-12T00:16:35Z","timestamp":1581466595000},"page":"893-903","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Dried Blood Spot Sampling of Landlocked Arctic Char (<i>Salvelinus alpinus<\/i>) for Estimating Mercury Exposure and Stable Carbon Isotope Fingerprinting of Essential Amino Acids"],"prefix":"10.1093","volume":"39","author":[{"given":"Benjamin D.","family":"Barst","sequence":"first","affiliation":[{"name":"Alaska Stable Isotope Facility Water and Environmental Research Center, Institute of Northern Engineering, University of Alaska Fairbanks Fairbanks Alaska USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew J.","family":"Wooller","sequence":"additional","affiliation":[{"name":"College of Fisheries and Ocean Sciences University of Alaska Fairbanks Fairbanks Alaska USA"},{"name":"Alaska Stable Isotope Facility Water and Environmental Research Center, Institute of Northern Engineering, University of Alaska Fairbanks Fairbanks Alaska USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diane M.","family":"O'Brien","sequence":"additional","affiliation":[{"name":"Center for Alaska Native Health Research Institute of Arctic Biology, University of Alaska Fairbanks Fairbanks Alaska USA"},{"name":"Biology and Wildlife Department University of Alaska Fairbanks Fairbanks Alaska USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Santa-Rios","sequence":"additional","affiliation":[{"name":"Faculty of Agricultural and Environmental Sciences McGill University, Sainte-Anne-de-Bellevue Quebec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2695-1037","authenticated-orcid":false,"given":"Niladri","family":"Basu","sequence":"additional","affiliation":[{"name":"Faculty of Agricultural and Environmental Sciences McGill University, Sainte-Anne-de-Bellevue Quebec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G\u00fcnter","family":"K\u00f6ck","sequence":"additional","affiliation":[{"name":"Institute for Interdisciplinary Mountain Research (\u00d6AW-IGF) Innsbruck Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica J.","family":"Johnson","sequence":"additional","affiliation":[{"name":"Biology and Wildlife Department University of Alaska Fairbanks Fairbanks Alaska USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Derek C.G.","family":"Muir","sequence":"additional","affiliation":[{"name":"Aquatic Contaminants Research Division Environment Canada, Burlington Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2020,2,11]]},"reference":[{"key":"2025010314064819400_etc4686-bib-0001","author":"Arctic Monitoring and Assessment Program","year":"2011"},{"key":"2025010314064819400_etc4686-bib-0002","author":"Arctic Monitoring and Assessment Programme, United Nations Environment Programme","year":"2013"},{"key":"2025010314064819400_etc4686-bib-0003","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1002\/etc.4341","article-title":"Screening-level risk assessment of methylmercury for non-anadromous Arctic char (Salvelinus alpinus)","volume":"38","author":"Barst","year":"2019","journal-title":"Environ Toxicol Chem"},{"key":"2025010314064819400_etc4686-bib-0004","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1016\/j.envpol.2016.03.003","article-title":"Subcellular distribution of trace elements and liver histology of landlocked Arctic char (Salvelinus alpinus) sampled along a mercury contamination gradient","volume":"212","author":"Barst","year":"2016","journal-title":"Environ Pollut"},{"key":"2025010314064819400_etc4686-bib-0005","volume-title":"Investigation of the toxic effects of mercury in Arctic char. Synopsis of research conducted under the 2016\u20132017 Northern Contaminants Program","author":"Basu","year":"2017"},{"key":"2025010314064819400_etc4686-bib-0006","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1016\/j.envres.2017.08.021","article-title":"Development and application of a novel method to characterize methylmercury exposure in newborns using dried blood spots","volume":"159","author":"Basu","year":"2017","journal-title":"Environ Res"},{"key":"2025010314064819400_etc4686-bib-0007","doi-asserted-by":"crossref","first-page":"106001","DOI":"10.1289\/EHP3904","article-title":"A state-of-the-science review of mercury biomarkers in human populations worldwide between 2000 and 2018","volume":"126","author":"Basu","year":"2018","journal-title":"Environ Health Perspect"},{"key":"2025010314064819400_etc4686-bib-0008","doi-asserted-by":"crossref","first-page":"7641","DOI":"10.1021\/acs.est.5b01033","article-title":"Ice core perspective on mercury pollution during the past 600 years","volume":"49","author":"Beal","year":"2015","journal-title":"Environ Sci Technol"},{"key":"2025010314064819400_etc4686-bib-0009","doi-asserted-by":"crossref","first-page":"2284","DOI":"10.1139\/z90-319","article-title":"Winter condition and proximate composition of anadromous Arctic charr (Salvelinus alpinus) in eastern Ungava Bay, Quebec","volume":"68","author":"Boivin","year":"1990","journal-title":"Can J Zool"},{"key":"2025010314064819400_etc4686-bib-0010","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1139\/F09-196","article-title":"Turnover and fractionation of carbon and nitrogen stable isotopes in tissues of a migratory coastal predator, summer flounder (Paralichthys dentatus)","volume":"67","author":"Buchheister","year":"2010","journal-title":"Can J Fish Aquat Sci"},{"key":"2025010314064819400_etc4686-bib-0011","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1038\/jes.2008.19","article-title":"Pilot study for utilization of dried blood spots for screening of lead, mercury and cadmium in newborns","volume":"19","author":"Chaudhuri","year":"2009","journal-title":"J Expo Sci Environ Epidemiol"},{"key":"2025010314064819400_etc4686-bib-0012","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.scitotenv.2014.05.151","article-title":"Mercury in freshwater ecosystems of the Canadian Arctic: Recent advances on its cycling and fate","volume":"509","author":"Ch\u00e9telat","year":"2015","journal-title":"Sci Total Environ"},{"key":"2025010314064819400_etc4686-bib-0013","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.1007\/s00300-010-0797-9","article-title":"Carbon sources for lake food webs in the Canadian High Arctic and other regions of Arctic North America","volume":"33","author":"Ch\u00e9telat","year":"2010","journal-title":"Polar Biol"},{"key":"2025010314064819400_etc4686-bib-0014","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1021\/acs.est.7b04180","article-title":"Ratio of methylmercury to dissolved organic carbon in water explains methylmercury bioaccumulation across a latitudinal gradient from north-temperate to arctic lakes","volume":"52","author":"Ch\u00e9telat","year":"2017","journal-title":"Environ Sci Technol"},{"key":"2025010314064819400_etc4686-bib-0016","doi-asserted-by":"crossref","first-page":"9082","DOI":"10.1021\/ac071223b","article-title":"Development of N-acetyl methyl ester derivatives for the determination of \u03b413C values of amino acids using gas chromatography-combustion-isotope ratio mass spectrometry","volume":"79","author":"Corr","year":"2007","journal-title":"Anal Chem"},{"key":"2025010314064819400_etc4686-bib-0017","doi-asserted-by":"crossref","first-page":"3692","DOI":"10.1111\/gcb.14129","article-title":"Global change\u2013driven effects on dissolved organic matter composition: Implications for food webs of northern lakes","volume":"24","author":"Creed","year":"2018","journal-title":"Glob Chang Biol"},{"key":"2025010314064819400_etc4686-bib-0018","doi-asserted-by":"crossref","first-page":"6120","DOI":"10.1016\/j.scitotenv.2009.08.036","article-title":"Anthropogenic contributions to mercury levels in present-day arctic animals\u2014A review","volume":"407","author":"Dietz","year":"2009","journal-title":"Sci Total Environ"},{"key":"2025010314064819400_etc4686-bib-0019","doi-asserted-by":"crossref","first-page":"888","DOI":"10.1016\/j.scitotenv.2016.05.001","article-title":"Evaluating the effectiveness of the Minamata Convention on Mercury: Principles and recommendations for next steps","volume":"569","author":"Evers","year":"2016","journal-title":"Sci Total Environ"},{"key":"2025010314064819400_etc4686-bib-0021","first-page":"337","article-title":"Natural stable carbon isotope tag traces Texas shrimp migrations","volume":"79","author":"Fry","year":"1981","journal-title":"Fish Bull"},{"key":"2025010314064819400_etc4686-bib-0020","doi-asserted-by":"crossref","first-page":"1182","DOI":"10.4319\/lo.1988.33.5.1182","article-title":"Food web structure on georges bank from stable C, N, and S isotopic compositions","volume":"33","author":"Fry","year":"1988","journal-title":"Limnol Oceanogr"},{"key":"2025010314064819400_etc4686-bib-0022","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1542\/peds.32.3.338","article-title":"A simple phenylalanine method for detecting phenylketonuria in large populations of newborn infants","volume":"32","author":"Guthrie","year":"1963","journal-title":"Pediatrics"},{"key":"2025010314064819400_etc4686-bib-0023","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1023\/A:1018071406537","article-title":"Food as the dominant pathway of methylmercury uptake by fish","volume":"100","author":"Hall","year":"1997","journal-title":"Water Air Soil Pollut"},{"key":"2025010314064819400_etc4686-bib-0024","doi-asserted-by":"crossref","first-page":"225","DOI":"10.2138\/gsrmg.43.1.225","article-title":"Fractionation of the isotopes of carbon and hydrogen in biosynthetic processes","volume":"43","author":"Hayes","year":"2001","journal-title":"Rev Mineral Geochem"},{"key":"2025010314064819400_etc4686-bib-0025","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1016\/j.scitotenv.2019.04.453","article-title":"Temporal trends, lake-to-lake variation, and climate effects on Arctic char (Salvelinus alpinus) mercury concentrations from six High Arctic lakes in Nunavut, Canada","volume":"678","author":"Hudelson","year":"2019","journal-title":"Sci Total Environ"},{"key":"2025010314064819400_etc4686-bib-0026","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/S1546-5098(11)31027-8","volume-title":"Homeostasis and Toxicology of Non-essential Metals","author":"Kidd","year":"2011"},{"key":"2025010314064819400_etc4686-bib-0027","doi-asserted-by":"crossref","first-page":"3526","DOI":"10.1890\/08-1695.1","article-title":"Stable isotope fingerprinting: A novel method for identifying plant, fungal, or bacterial origins of amino acids","volume":"90","author":"Larsen","year":"2009","journal-title":"Ecology"},{"key":"2025010314064819400_etc4686-bib-0028","doi-asserted-by":"crossref","first-page":"e73441","DOI":"10.1371\/journal.pone.0073441","article-title":"Tracing carbon sources through aquatic and terrestrial food webs using amino acid stable isotope fingerprinting","volume":"8","author":"Larsen","year":"2013","journal-title":"PLoS One"},{"key":"2025010314064819400_etc4686-bib-0029","doi-asserted-by":"crossref","first-page":"1541","DOI":"10.1002\/rcm.6259","article-title":"Can amino acid carbon isotope ratios distinguish primary producers in a mangrove ecosystem?","volume":"26","author":"Larsen","year":"2012","journal-title":"Rapid Commun Mass Spectrom"},{"key":"2025010314064819400_etc4686-bib-0030","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1093\/jat\/bkt048","article-title":"Diagnostic analysis of veterinary dried blood spots for toxic heavy metals exposure","volume":"37","author":"Lehner","year":"2013","journal-title":"J Anal Toxicol"},{"key":"2025010314064819400_etc4686-bib-0031","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.scitotenv.2014.04.133","article-title":"Factors affecting biotic mercury concentrations and biomagnification through lake food webs in the Canadian High Arctic","volume":"509","author":"Lescord","year":"2015","journal-title":"Sci Total Environ"},{"key":"2025010314064819400_etc4686-bib-0032","doi-asserted-by":"crossref","DOI":"10.1002\/9781118890837","volume-title":"Dried Blood Spots: Applications and Techniques","author":"Li","year":"2014"},{"key":"2025010314064819400_etc4686-bib-0033","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1016\/j.scitotenv.2004.11.027","article-title":"A history of total mercury in edible muscle of fish from lakes in northern Canada","volume":"351","author":"Lockhart","year":"2005","journal-title":"Sci Total Environ"},{"key":"2025010314064819400_etc4686-bib-0034","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1139\/as-2017-0019","article-title":"Financial costs of conducting science in the Arctic: Examples from seabird research","volume":"4","author":"Mallory","year":"2018","journal-title":"Arct Sci"},{"key":"2025010314064819400_etc4686-bib-0035","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1021\/es0612605","article-title":"Optimization of blood collection card method\/enzyme-linked immunoassay for monitoring exposure of bottlenose dolphin to brevetoxin-producing red tides","volume":"41","author":"Maucher","year":"2007","journal-title":"Environ Sci Technol"},{"key":"2025010314064819400_etc4686-bib-0036","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1111\/j.1365-2656.2010.01722.x","article-title":"Carbon isotope fractionation of amino acids in fish muscle reflects biosynthesis and isotopic routing from dietary protein","volume":"79","author":"McMahon","year":"2010","journal-title":"J Anim Ecol"},{"key":"2025010314064819400_etc4686-bib-0037","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1007\/s00442-015-3475-3","article-title":"Tracing carbon flow through coral reef food webs using a compound-specific stable isotope approach","volume":"180","author":"McMahon","year":"2016","journal-title":"Oecologia"},{"key":"2025010314064819400_etc4686-bib-0038","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1016\/j.scitotenv.2004.07.036","article-title":"Spatial and temporal trends of mercury and other metals in landlocked char from lakes in the Canadian Arctic archipelago","volume":"351","author":"Muir","year":"2005","journal-title":"Sci Total Environ"},{"key":"2025010314064819400_etc4686-bib-0039","doi-asserted-by":"crossref","first-page":"4413","DOI":"10.1073\/pnas.072346699","article-title":"Renewable and nonrenewable resources: Amino acid turnover and allocation to reproduction in lepidoptera","volume":"99","author":"O'Brien","year":"2002","journal-title":"Proc Natl Acad Sci USA"},{"key":"2025010314064819400_etc4686-bib-0040","doi-asserted-by":"crossref","first-page":"375","DOI":"10.7589\/2017-08-202","article-title":"Use of blood-soaked cellulose filter paper for measuring carbon and nitrogen stable isotopes","volume":"54","author":"O'Hara","year":"2018","journal-title":"J Wildl Dis"},{"key":"2025010314064819400_etc4686-bib-0041","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.orggeochem.2017.07.009","article-title":"Advances in the application of amino acid nitrogen isotopic analysis in ecological and biogeochemical studies","volume":"113","author":"Ohkouchi","year":"2017","journal-title":"Org Geochem"},{"key":"2025010314064819400_etc4686-bib-0042","doi-asserted-by":"crossref","first-page":"902","DOI":"10.1021\/es980242n","article-title":"Distribution kinetics of dietary methylmercury in the Arctic charr (Salvelinus alpinus)","volume":"33","author":"Oliveira Ribeiro","year":"1999","journal-title":"Environ Sci Technol"},{"key":"2025010314064819400_etc4686-bib-0043","doi-asserted-by":"crossref","first-page":"3289","DOI":"10.1002\/etc.3905","article-title":"Mercury speciation and subcellular distribution in experimentally dosed and wild birds","volume":"36","author":"Perkins","year":"2017","journal-title":"Environ Toxicol Chem"},{"key":"2025010314064819400_etc4686-bib-0044","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/j.envpol.2018.01.036","article-title":"Dried blood spots for estimating mercury exposure in birds","volume":"236","author":"Perkins","year":"2018","journal-title":"Environ Pollut"},{"key":"2025010314064819400_etc4686-bib-0045","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1890\/0012-9658(2002)083[0703:USITET]2.0.CO;2","article-title":"Using stable isotopes to estimate trophic position: Models, methods, and assumptions","volume":"83","author":"Post","year":"2002","journal-title":"Ecology"},{"key":"2025010314064819400_etc4686-bib-0046","first-page":"199","volume-title":"Nunavik and Nunatsiavut: From science to policy. An integrated regional impact study (IRIS) of climate change and modernization","author":"Power","year":"2012"},{"key":"2025010314064819400_etc4686-bib-0047","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1579\/0044-7447(2006)35[347:CCEOHO]2.0.CO;2","article-title":"Climate change effects on hydroecology of Arctic freshwater ecosystems","volume":"35","author":"Prowse","year":"2006","journal-title":"Ambio"},{"key":"2025010314064819400_etc4686-bib-0048","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/j.scitotenv.2013.02.095","article-title":"Maternal Steller sea lion diets elevate fetal mercury concentrations in an area of population decline","volume":"454","author":"Rea","year":"2013","journal-title":"Sci Total Environ"},{"key":"2025010314064819400_etc4686-bib-0049","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1080\/10256016.2019.1620742","article-title":"Sources of primary production to arctic bivalves identified using amino acid stable carbon isotope fingerprinting","volume":"55","author":"Rowe","year":"2019","journal-title":"Isotopes Environ Health Stud"},{"key":"2025010314064819400_etc4686-bib-0050","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1007\/s00244-011-9709-4","article-title":"Examination of Eurasian griffon vultures (Gyps fulvus fulvus) in Israel for exposure to environmental toxicants using dried blood spots","volume":"62","author":"Shlosberg","year":"2012","journal-title":"Arch Environ Contam Toxicol"},{"key":"2025010314064819400_etc4686-bib-0051","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1021\/ac00004a014","article-title":"Stable carbon isotope analysis of amino acid enantiomers by conventional isotope ratio mass spectrometry and combined gas chromatography\/isotope ratio mass spectrometry","volume":"63","author":"Silfer","year":"1991","journal-title":"Anal Chem"},{"key":"2025010314064819400_etc4686-bib-0052","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1021\/acs.est.8b05926","article-title":"Drivers of mercury cycling in the rapidly changing glacierized watershed of the High Arctic's largest lake by volume (Lake Hazen, Nunavut, Canada)","volume":"53","author":"St. Pierre","year":"2018","journal-title":"Environ Sci Technol"},{"key":"2025010314064819400_etc4686-bib-0053","doi-asserted-by":"crossref","first-page":"14099","DOI":"10.1021\/acs.est.8b05348","article-title":"Unprecedented increases in total and methyl mercury concentrations downstream of retrogressive thaw slumps in the western Canadian Arctic","volume":"52","author":"St. Pierre","year":"2018","journal-title":"Environ Sci Technol"},{"key":"2025010314064819400_etc4686-bib-0054","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1373\/clinchem.2006.076679","article-title":"Long-term stability of amino acids and acylcarnitines in dried blood spots","volume":"53","author":"Strnadova","year":"2007","journal-title":"Clin Chem"},{"key":"2025010314064819400_etc4686-bib-0055","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1007\/BF00379558","article-title":"Fractionation and turnover of stable carbon isotopes in animal tissues: Implications for \u03b413C analysis of diet","volume":"57","author":"Tieszen","year":"1983","journal-title":"Oecologia"},{"key":"2025010314064819400_etc4686-bib-0056","doi-asserted-by":"crossref","first-page":"1","DOI":"10.20454\/jeaas.2016.1077","article-title":"Individual measurement of gene expression in blood cells from rainbow trout Oncorhynchus mykiss (Walbaum)","volume":"2","author":"Urquhart","year":"2016","journal-title":"J Exp Appl Anim Sci"},{"key":"2025010314064819400_etc4686-bib-0057","author":"US Environmental Protection Agency","year":"2007"},{"key":"2025010314064819400_etc4686-bib-0058","doi-asserted-by":"crossref","first-page":"5895","DOI":"10.1021\/es070395n","article-title":"Elimination of mercury by yellow perch in the wild","volume":"41","author":"Van Walleghem","year":"2007","journal-title":"Environ Sci Technol"},{"key":"2025010314064819400_etc4686-bib-0059","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1289\/ehp.7274","article-title":"Uptake and elimination of brevetoxin in blood of striped mullet (Mugil cephalus) after aqueous exposure to Karenia brevis","volume":"113","author":"Woofter","year":"2004","journal-title":"Environ Health Perspect"}],"container-title":["Environmental Toxicology and Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fetc.4686","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/etc.4686","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/etc.4686","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/academic.oup.com\/etc\/article-pdf\/39\/4\/893\/59780539\/etc4686.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/etc\/article-pdf\/39\/4\/893\/59780539\/etc4686.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,3]],"date-time":"2025-01-03T14:49:02Z","timestamp":1735915742000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/etc\/article\/39\/4\/893\/7735560"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2,11]]},"references-count":58,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2020,2,11]]},"published-print":{"date-parts":[[2020,2,11]]}},"URL":"https:\/\/doi.org\/10.1002\/etc.4686","relation":{},"ISSN":["0730-7268","1552-8618"],"issn-type":[{"value":"0730-7268","type":"print"},{"value":"1552-8618","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2020,4,1]]},"published":{"date-parts":[[2020,2,11]]},"assertion":[{"value":"2019-11-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-02-08","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-03-22","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}