{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T05:12:20Z","timestamp":1786597940657,"version":"build-2736575974"},"reference-count":28,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2021,4,30]],"date-time":"2021-04-30T00:00:00Z","timestamp":1619740800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"},{"start":{"date-parts":[[2021,7,16]],"date-time":"2021-07-16T00:00:00Z","timestamp":1626393600000},"content-version":"vor","delay-in-days":77,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Department of Defense, SERDP","award":["ER-2431"],"award-info":[{"award-number":["ER-2431"]}]},{"name":"Washington DC Department of Energy and Environment"}],"content-domain":{"domain":["setac.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,4,30]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Bioaccumulation of hydrophobic pollutants in an aquatic food web is governed by exposure concentrations in sediment and water phases and by complex trophic interactions among the various species. We demonstrate that biological interactions and exposure from the chemical environment can be deconvoluted for aquatic food webs to allow clearer assessments of the role of thermodynamic drivers from the sediment and surface water phases. We first demonstrate the feasibility of this deconvolution mathematically for hypothetical food webs with 3 and 4 interacting species and for more realistic real-world food webs with &amp;gt;10 species of aquatic organisms (i.e., the freshwater lake food web in Western Lake Erie [ON, Canada] and the marine food web in New Bedford Harbor [MA, USA]). Our results show both mathematically (for the simple food webs) and computationally (for the more complex food webs) that a deconvoluted food web model parameterized for site-specific conditions can predict the bioaccumulation of polychlorinated biphenyls in aquatic organisms same as existing complex food web models. The merit of this approach is that once the thermodynamic and biological contributions to food web bioaccumulation are computed for an ecosystem, the deconvoluted model provides a relatively simple approach for calculating concentrations of chemicals in organisms for a range of possible surface water and sedimentary concentrations. This approach is especially useful for calculating bioaccumulation of pollutants from freely dissolved concentrations measured using passive sampling devices or predicted by fate and transport models. The deconvoluted approach makes it possible to develop regulatory guidelines for a set of surface water and sediment (or porewater) concentration combinations for a water body that is able to achieve a risk-based target for fish concentration.\u00a0Environ Toxicol Chem 2021;40:2145\u20132155. \u00a9 2021 SETAC.<\/jats:p>\n               <jats:p>Abstract<\/jats:p>\n               <jats:p>Thermodynamic influences of surface water and porewater separated mathematically from complex food web interactions. Csw and Cpw\u2009=\u2009dissolved concentrations of the hydrophobic organic contaminants in surface water and sediment porewater, respectively; fsw and fpw\u2009=\u2009fractional influence of surface water and porewater, respectively; BAFfish,A\u2009=\u2009bioaccumulation factor for Fish A.<\/jats:p>","DOI":"10.1002\/etc.5106","type":"journal-article","created":{"date-parts":[[2021,4,30]],"date-time":"2021-04-30T20:01:27Z","timestamp":1619812887000},"page":"2145-2155","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Deconvoluting Thermodynamics from Biology in the Aquatic Food Web Model"],"prefix":"10.1093","volume":"40","author":[{"given":"Upal","family":"Ghosh","sequence":"first","affiliation":[{"name":"Department of Chemical, Biochemical, and Environmental Engineering University of Maryland Baltimore County Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mandar","family":"Bokare","sequence":"additional","affiliation":[{"name":"Department of Chemical, Biochemical, and Environmental Engineering University of Maryland Baltimore County Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7829-8260","authenticated-orcid":false,"given":"Frank A.P.C.","family":"Gobas","sequence":"additional","affiliation":[{"name":"Resource and Environment Management Simon Fraser University Burnaby British Columbia Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2021,4,30]]},"reference":[{"key":"2025010313400056100_etc5106-bib-0001","doi-asserted-by":"crossref","first-page":"12655","DOI":"10.1021\/es303062q","article-title":"Habitat-based PCB environmental quality criteria for the protection of endangered killer whales (Orcinus orca)","volume":"46","author":"Alava","year":"2012","journal-title":"Environ Sci Technol"},{"key":"2025010313400056100_etc5106-bib-0002","author":"ARC Arnot Research and Consulting","year":"2012"},{"key":"2025010313400056100_etc5106-bib-0003","doi-asserted-by":"crossref","first-page":"2343","DOI":"10.1897\/03-438","article-title":"A food web bioaccumulation model for organic chemicals in aquatic ecosystems","volume":"23","author":"Arnot","year":"2004","journal-title":"Environ Toxicol Chem"},{"key":"2025010313400056100_etc5106-bib-0004","author":"Burkhard","year":"2013"},{"key":"2025010313400056100_etc5106-bib-0005","first-page":"1","author":"Burkhard","year":"2004"},{"key":"2025010313400056100_etc5106-bib-0006","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1021\/es00016a022","article-title":"Application of a food chain model to polychlorinated biphenyl contamination of the lobster and winter flounder food chains in New Bedford Harbor","volume":"25","author":"Connolly","year":"1991","journal-title":"Environ Sci Technol"},{"key":"2025010313400056100_etc5106-bib-0007","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1021\/es00166a011","article-title":"A thermodynamic-based evaluation of organic chemical accumulation in aquatic organisms","volume":"22","author":"Connolly","year":"1988","journal-title":"Environ Sci Technol"},{"key":"2025010313400056100_etc5106-bib-0008","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1007\/BF01065333","article-title":"The biomagnification of polychlorinated biphenyls, toxaphene, and DDT compounds in a Lake Michigan offshore food web","volume":"20","author":"Evans","year":"1991","journal-title":"Arch Environ Contam Toxicol"},{"key":"2025010313400056100_etc5106-bib-0009","doi-asserted-by":"crossref","first-page":"3480","DOI":"10.1002\/etc.3932","article-title":"Assimilation efficiency of sediment-bound PCBs ingested by fish impacted by strong sorption","volume":"36","author":"Fadaei","year":"2017","journal-title":"Environ Toxicol Chem"},{"key":"2025010313400056100_etc5106-bib-0010","doi-asserted-by":"crossref","first-page":"2908","DOI":"10.1897\/04-566R.1","article-title":"Bioconcentration of persistent organic pollutants in four species of marine phytoplankton","volume":"24","author":"Gerofke","year":"2005","journal-title":"Environ Toxicol Chem"},{"key":"2025010313400056100_etc5106-bib-0011","author":"Ghosh","year":"2020"},{"key":"2025010313400056100_etc5106-bib-0012","doi-asserted-by":"crossref","first-page":"2326","DOI":"10.1002\/etc.4526","article-title":"Bioaccumulation in functionally different species: Ongoing input of PCBs with sediment deposition to activated carbon remediated bed sediments","volume":"38","author":"Gidley","year":"2019","journal-title":"Environ Toxicol Chem"},{"key":"2025010313400056100_etc5106-bib-0013","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0304-3800(93)90045-T","article-title":"A model for predicting the bioaccumulation of hydrophobic organic chemicals in aquatic food-webs: Application to Lake Ontario","volume":"69","author":"Gobas","year":"1993","journal-title":"Ecol Model"},{"key":"2025010313400056100_etc5106-bib-0014","doi-asserted-by":"crossref","first-page":"1385","DOI":"10.1002\/etc.164","article-title":"Food web bioaccumulation model for polychlorinated biphenyls in San Francisco Bay, California, USA","volume":"29","author":"Gobas","year":"2010","journal-title":"Environ Toxicol Chem"},{"key":"2025010313400056100_etc5106-bib-0015","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1016\/0045-6535(88)90066-5","article-title":"Dynamics of dietary bioaccumulation and faecal elimination of hydrophobic organic chemicals in fish","volume":"17","author":"Gobas","year":"1988","journal-title":"Chemosphere"},{"key":"2025010313400056100_etc5106-bib-0016","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1021\/es980681m","article-title":"Mechanism of biomagnification in fish under laboratory and field conditions","volume":"33","author":"Gobas","year":"1999","journal-title":"Environ Sci Technol"},{"key":"2025010313400056100_etc5106-bib-0017","doi-asserted-by":"crossref","first-page":"2551","DOI":"10.1897\/03-400","article-title":"Dependency of polychlorinated biphenyl and polycyclic aromatic hydrocarbon bioaccumulation in Mya arenaria on both water column and sediment bed chemical activities","volume":"23","author":"Lohmann","year":"2004","journal-title":"Environ Toxicol Chem"},{"key":"2025010313400056100_etc5106-bib-0018","doi-asserted-by":"crossref","first-page":"11103","DOI":"10.1021\/acs.est.6b03169","article-title":"Ecological implications of steady state and nonsteady state bioaccumulation models","volume":"50","author":"Mcleod","year":"2016","journal-title":"Environ Sci Technol"},{"key":"2025010313400056100_etc5106-bib-0019","doi-asserted-by":"crossref","first-page":"3267","DOI":"10.1021\/es970265m","article-title":"Development and verification of a benthic\/pelagic food web bioaccumulation model for PCB congeners in Western Lake Erie","volume":"31","author":"Morrison","year":"1997","journal-title":"Environ Sci Technol"},{"key":"2025010313400056100_etc5106-bib-0020","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1016\/j.envpol.2018.12.016","article-title":"Four decades since the ban, old urban wastewater treatment plant remains a dominant source of PCBs to the environment","volume":"246","author":"Needham","year":"2019","journal-title":"Environ Pollut"},{"key":"2025010313400056100_etc5106-bib-0021","doi-asserted-by":"crossref","first-page":"9729","DOI":"10.1021\/acs.est.9b07292","article-title":"Evaluating polymeric sampling as a tool for predicting the bioaccumulation of polychlorinated biphenyls by fish and shellfish","volume":"54","author":"Schmidt","year":"2020","journal-title":"Environ Sci Technol"},{"key":"2025010313400056100_etc5106-bib-0022","doi-asserted-by":"crossref","first-page":"4001","DOI":"10.1016\/0045-6535(95)80001-2","article-title":"Algal density dependent bioconcentration factors of hydrophobic chemicals","volume":"31","author":"Sijm","year":"1995","journal-title":"Chemosphere"},{"key":"2025010313400056100_etc5106-bib-0023","first-page":"1849","article-title":"Factors affecting phytoplankton species-specific differences in accumulation of 40 polychlorinated biphenyls (PCBs)","volume":"13","author":"Stange","year":"1994","journal-title":"Environ Toxicol Chem"},{"key":"2025010313400056100_etc5106-bib-0024","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1002\/etc.5620120506","article-title":"Bioaccumulation of PCBs by algae: Kinetics versus equilibrium","volume":"12","author":"Swackhamer","year":"1993","journal-title":"Environ Toxicol Chem"},{"key":"2025010313400056100_etc5106-bib-0025","author":"The Louis Berger Group, Battelle, HDR\/HydroQual","year":"2014"},{"key":"2025010313400056100_etc5106-bib-0026","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1007\/BF00213397","article-title":"Use of biota-sediment accumulation factors to assess similarity of nonionic organic chemical exposure to benthically-coupled organisms of differing trophic mode","volume":"30","author":"Tracey","year":"1996","journal-title":"Arch Environ Contam Toxicol"},{"key":"2025010313400056100_etc5106-bib-0027","author":"US Environmental Protection Agency","year":"2019"},{"key":"2025010313400056100_etc5106-bib-0028","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1016\/j.envpol.2008.11.001","article-title":"Biomagnification of polybrominated diphenyl ethers (PBDEs) and polychlorinated biphenyls in a highly contaminated freshwater food web from South China","volume":"157","author":"Wu","year":"2009","journal-title":"Environ Pollut"}],"container-title":["Environmental Toxicology and Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/etc.5106","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/etc.5106","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/academic.oup.com\/etc\/article-pdf\/40\/8\/2145\/59784558\/etc5106.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/etc\/article-pdf\/40\/8\/2145\/59784558\/etc5106.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,3]],"date-time":"2025-01-03T14:21:43Z","timestamp":1735914103000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/etc\/article\/40\/8\/2145\/7734361"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4,30]]},"references-count":28,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2021,4,30]]},"published-print":{"date-parts":[[2021,4,30]]}},"URL":"https:\/\/doi.org\/10.1002\/etc.5106","relation":{},"ISSN":["0730-7268","1552-8618"],"issn-type":[{"value":"0730-7268","type":"print"},{"value":"1552-8618","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2021,8,1]]},"published":{"date-parts":[[2021,4,30]]},"assertion":[{"value":"2020-12-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-04-26","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-07-16","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}