{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T06:39:12Z","timestamp":1770359952032,"version":"3.49.0"},"reference-count":32,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2022,12,29]],"date-time":"2022-12-29T00:00:00Z","timestamp":1672272000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"},{"start":{"date-parts":[[2023,1,30]],"date-time":"2023-01-30T00:00:00Z","timestamp":1675036800000},"content-version":"vor","delay-in-days":32,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["setac.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,3,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Japanese medaka is specified as a model fish in the test guidelines of the Organisation for Economic Co-operation and Development. Recently, populations of Japanese medaka in Japan were divided into two species, the northern Oryzias sakaizumii and the southern O. latipes. Previously, we reported that induction concentrations for sex reversal by exposure to 17\u03b1-methyltestosterone differed significantly between these two species, indicating that they respond differently to endocrine-disrupting chemica. In the present study, we examined the effects of exposure to two more endocrine-disrupting chemicals (bisphenol A and 17\u03b2-trenbolone) in O. sakaizumii, and compared the results with those previously reported for O. latipes. Exposure to both bisphenol A and 17\u03b2-trenbolone induced testis\u2013ova formation or sex reversal in O. sakaizumii. Exposure to 17\u03b2-trenbolone also increased expression of gonadal soma-derived factor (gsdf). Least-observed-effect concentrations for gonadal sex differentiation and gsdf expression were lower for O. latipes than for O. sakaizumii after exposure to bisphenol A, and were lower for O. sakaizumii than for O. latipes after exposure to 17\u03b2-trenbolone. These results demonstrate that O. sakaizumii and O. latipes respond differently to androgenic and estrogenic endocrine-disrupting chemicals. Environ Toxicol Chem 2023;42:673\u2013678. \u00a9 2022 SETAC<\/jats:p>","DOI":"10.1002\/etc.5552","type":"journal-article","created":{"date-parts":[[2022,12,30]],"date-time":"2022-12-30T06:49:10Z","timestamp":1672382950000},"page":"673-678","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Influence of Bisphenol A and 17\u03b2-Trenbolone Exposure in <i>Oryzias<\/i> Congeners"],"prefix":"10.1093","volume":"42","author":[{"given":"Yoshifumi","family":"Horie","sequence":"first","affiliation":[{"name":"Research Center for Inland Seas Kobe University Kobe Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takashi","family":"Chiba","sequence":"additional","affiliation":[{"name":"Department of Environmental and Symbiotic Science Rakuno Gakuen University Hokkaido Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2022,12,29]]},"reference":[{"key":"2025010313380831000_etc5552-bib-0001","first-page":"289","article-title":"Oryzias sakaizumii, a new ricefish from northern Japan (Teleostei: Adrianichthyidae)","volume":"22","author":"Asai","year":"2011","journal-title":"Ichthyological Exploration of Freshwaters"},{"key":"2025010313380831000_etc5552-bib-0002","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.aquatox.2012.11.016","article-title":"The maturity index as a tool to facilitate the interpretation of changes in vitellogenin production and sex ratio in the Fish Sexual Development Test","volume":"128\u2013129","author":"Baumann","year":"2013","journal-title":"Aquatic Toxicology"},{"key":"2025010313380831000_etc5552-bib-0003","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1016\/j.chemosphere.2016.11.089","article-title":"Developmental bisphenol A exposure 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