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Nonylphenol ethoxylate (NPEOn) is one such contaminant, along with its degradation product, nonylphenol, an active ingredient presents in nonionic surfactants used as herbicides, cosmetics, paints, plastics, disinfectants, and detergents. These chemicals and their metabolites are commonly found in environmental matrices. Nonylphenol and NPEOn, used, are particularly concerning, given their role as endocrine disruptors chemical and possible neurotoxic effects recorded in several biological models, primarily aquatic organisms. Limiting and detecting these compounds remain of paramount importance. The objective of the present review was to evaluate the toxic effects of nonylphenol and NPEOn in different biological models. Environ Toxicol Chem 2023;42:1439\u20131450. \u00a9 2023 SETAC<\/jats:p>","DOI":"10.1002\/etc.5633","type":"journal-article","created":{"date-parts":[[2023,4,14]],"date-time":"2023-04-14T08:16:28Z","timestamp":1681460188000},"page":"1439-1450","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":35,"title":["Studies of Endocrine Disruptors: Nonylphenol and Isomers in Biological Models"],"prefix":"10.1093","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0074-3149","authenticated-orcid":false,"given":"Ana C.","family":"De la Parra-Guerra","sequence":"first","affiliation":[{"name":"Biodiversity Research Group, Faculty of Basic Sciences Universidad del Atl\u00e1ntico Barranquilla Colombia"},{"name":"Department of Natural and Exact Sciences Universidad de La Costa Barranquilla Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosa","family":"Acevedo-Barrios","sequence":"additional","affiliation":[{"name":"Grupo de Investigaci\u00f3n en Estudios Qu\u00edmicos y Biol\u00f3gicos, Facultad de Ciencias B\u00e1sicas Universidad Tecnol\u00f3gica de Bol\u00edvar Cartagena Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,4,14]]},"reference":[{"key":"2025010313383151800_etc5633-bib-0001","doi-asserted-by":"crossref","first-page":"101200","DOI":"10.1016\/j.aqrep.2022.101200","article-title":"Palliative effect of dietary common sage leaves against toxic impacts of nonylphenol in mirror carp (Cyprinus carpio var specularis): Growth, gene expression, immune-antioxidant status, and histopathological alterations","volume":"25","author":"Abdel Rahman","year":"2022","journal-title":"Aquaculture 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