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Log kIAM is an alternative measure of hydrophobicity to the octanol\/water partition coefficient (log\u2009KOW). While there are several accepted methods to measure log KOW, no standardized method exists to determine log kIAM. The database of collated log kIAM values includes 13 key experimental parameters and contains 1,686 values for 555 compounds, which are predominantly polar organic compounds and include drug molecules and surfactants. These compounds are acidic, basic, and neutral and both ionized and un-ionized under the conditions of analysis. The data compiled demonstrated experimental variability for each experimental parameter considered, including column stationary phase, pH, temperature, and mobile phase. Reducing the experimental variability allowed for greater consistency in the datasets. Environ. Toxicol. Chem. 2011;30:2701\u20132708. \u00a9 2011 SETAC<\/jats:p>","DOI":"10.1002\/etc.677","type":"journal-article","created":{"date-parts":[[2011,9,15]],"date-time":"2011-09-15T04:05:46Z","timestamp":1316059546000},"page":"2701-2708","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Database of published retention factors for immobilized artificial membrane HPLC and an assessment of the effect of experimental variability"],"prefix":"10.1093","volume":"30","author":[{"given":"M.R","family":"Ledbetter","sequence":"first","affiliation":[{"name":"School of Pharmacy and Chemistry, Liverpool John Moores University, Liverpool, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"Gutsell","sequence":"additional","affiliation":[{"name":"Safety and Environmental Assurance Centre, Unilever Research, Sharnbrook, Bedfordshire, 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