{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T06:56:02Z","timestamp":1790837762137,"version":"4.1.0"},"reference-count":32,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T00:00:00Z","timestamp":1790726400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T00:00:00Z","timestamp":1790726400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100000836","name":"University of Liverpool","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000836","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["beva.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Equine Veterinary Journal"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Peritonitis is life\u2010threatening, and limited information exists regarding outcomes and predictors of survival.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To report short\u2010 and long\u2010term outcomes in horses diagnosed with peritonitis and identify factors associated with survival.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Design<\/jats:title>\n                    <jats:p>Retrospective observational.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Data were obtained for horses admitted to a UK referral hospital between 2010 and 2024 diagnosed with peritonitis (peritoneal fluid nucleated cell count &gt;10 \u00d7\u200910\n                      <jats:sup>9<\/jats:sup>\n                      \/L). Short\u2010 and long\u2010term morbidity and mortality were assessed. Multivariable logistic regression was used to identify factors associated with short\u2010term survival based on data available at admission (Model 1) and at the time of second abdominocentesis (Model 2).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Peritonitis was diagnosed in 123 horses. Overall, short\u2010term survival was 74% (91\/123) with better outcomes in primary (90%, 66\/73) versus secondary peritonitis (50%, 25\/50). Surgery was performed in 31 cases, with short\u2010term survival of 48% (15\/31). In model 1, horses with higher heart rates (OR 0.90, 95% CI 0.86\u20130.95,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) and sanguinous peritoneal fluid (OR 0.16, 95% CI 0.04\u20130.65,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.01) were significantly less likely to survive to hospital discharge. Survival was better in ponies vs. horses (OR 8.30, 95% CI 1.42\u201348.60,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.02), and if rectal examination was normal (OR 8.25, 95% CI 1.80\u201337.85,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.007). In Model 2, increased heart rate was the best predictor of reduced survival (OR 0.89, 95% CI 0.83\u20130.94,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Survival to 30, 90, and 365\u2009days was 98% (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200950\/51), 93% (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200942\/45), and 88% (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200935\/40), respectively. A third of horses developed complications following hospital discharge (predominantly colic and pyrexia), usually within 90\u2009days of hospital admission. Peritonitis recurred in 6 horses.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main Limitations<\/jats:title>\n                    <jats:p>Retrospective study from a single hospital population.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The prognosis for primary peritonitis is better than secondary peritonitis. Heart rate is a good predictor of short\u2010term survival at admission and time of repeat abdominocentesis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/evj.70339","type":"journal-article","created":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T06:05:37Z","timestamp":1790834737000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Predicting outcomes in equine peritonitis: Multivariable analysis of admission and post\u2010admission data from a\n                    <scp>UK<\/scp>\n                    hospital population"],"prefix":"10.1002","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0492-7578","authenticated-orcid":false,"given":"E. K.","family":"Kopec","sequence":"first","affiliation":[{"name":"Philip Leverhulme Equine Hospital University of Liverpool  Cheshire UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Carslake","sequence":"additional","affiliation":[{"name":"Philip Leverhulme Equine Hospital University of Liverpool  Cheshire UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4421-9269","authenticated-orcid":false,"given":"D. C.","family":"Archer","sequence":"additional","affiliation":[{"name":"Philip Leverhulme Equine Hospital University of Liverpool  Cheshire UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Morris","sequence":"additional","affiliation":[{"name":"Philip Leverhulme Equine Hospital University of Liverpool  Cheshire UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Wilson","sequence":"additional","affiliation":[{"name":"Philip Leverhulme Equine Hospital University of Liverpool  Cheshire UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,30]]},"reference":[{"issue":"2","key":"e_1_2_13_2_1","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1111\/vsu.13564","article-title":"Clinical and diagnostic findings, treatment, and short\u2010 and long\u2010term survival in horses with peritonitis: 72 cases (2007\u20132017)","volume":"50","author":"Arndt 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