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Inorganic biomaterials with tunable properties may deliver multiple physicochemical cues for bioenergy\u2010activation. However, there is currently a lack of systematic design and study on inorganic biomaterials\u2010derived physicochemical cues for myocardial bioenergy\u2010activation. This study proposes a bioenergy\u2010activating bioink based on inorganic biomaterials. Through the dual design of the chemical composition and physical morphology cues, the bioinks containing magnesium silicate (MS) nanoparticles with different morphologies were developed, and the corresponding 3D bioprinted cardiac patches were prepared. It was found that the magnesium and silicon components of MS are well beneficial to ATP production and myocardial maturation. 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