{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,23]],"date-time":"2023-10-23T06:55:49Z","timestamp":1698044149711},"reference-count":14,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2006,10,19]],"date-time":"2006-10-19T00:00:00Z","timestamp":1161216000000},"content-version":"vor","delay-in-days":8327,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nahrung"],"published-print":{"date-parts":[[1984,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Die H\u00f6he der \u03b2\u2010Galaktosidase\u2010Aktivit\u00e4t von Bifidobakterien wird unter in vitro\u2010Kultivierungsbedingungen wesentlich von der Zusammensetzung des N\u00e4hrbodens beeinflu\u00dft. Durch den Einsatz gnotobiotischer (keimfreier und mit <jats:italic>Bifidobacterium longum<\/jats:italic> monoassoziierter) Ratten lie\u00df sich im Chymus zwischen der \u03b2\u2010Galaktosidase\u2010Aktivit\u00e4t mucosalen und mikrobiellen Ursprungs differenzieren. Bei keimfreien Tieren findet man im Chymus von D\u00fcnn\u2010 und Dickdarm etwa 10\u201320% der auf g Feuchtmasse bezogenen Aktivit\u00e4t, die in der Mucosa gemessen wird. Monoassoziation mit <jats:italic>B. longum<\/jats:italic> beeinflu\u00dft die lactosespaltende Aktivit\u00e4t des D\u00fcnndarminhalts nicht, steigert jedoch die Aktivit\u00e4t des Dickdarminhalts auf den 2fachen Wert der mucosalen Aktivit\u00e4t. Die Verf\u00fctterung von Lactose f\u00fchrt bei den monoassoziierten Tieren im Inhalt von Caecum und Colon sowie in den Faeces zu einer weiteren mehrfachen Erh\u00f6hung der \u03b2\u2010Galaktosidase\u2010Aktivit\u00e4t.<\/jats:p>","DOI":"10.1002\/food.19840280429","type":"journal-article","created":{"date-parts":[[2006,11,2]],"date-time":"2006-11-02T22:40:23Z","timestamp":1162507223000},"page":"449-455","source":"Crossref","is-referenced-by-count":5,"title":["Einsatz der gnotobiotischen Ratte zur Erfassung der in vivo\u2010Aktivit\u00e4t von Bifidobacterium\u2010\u03b2\u2010Galaktosidase"],"prefix":"10.1002","volume":"28","author":[{"given":"J.","family":"Schulze","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Herzog","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.\u2010J.","family":"Zunft","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.\u2010K.","family":"Gr\u00fctte","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,10,19]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"481","volume-title":"Carbohydrate metabolism and its disorders","author":"Koldovsky O.","year":"1981"},{"key":"e_1_2_1_3_2","first-page":"170","volume":"48","author":"Adrian J.","year":"1978","journal-title":"Intern. Z. Vitamin\u2010 u. Ern\u00e4hr.\u2010Forsch."},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/109.5.856"},{"key":"e_1_2_1_5_2","series-title":"Bibl. Nutrit. Dieta 31","first-page":"40","volume-title":"Nutrition in early childhood and its effects in later life","author":"Gr\u00fctte F.\u2010K.","year":"1982"},{"key":"e_1_2_1_6_2","first-page":"64","article-title":"Mikro\u00f6kologie des Magen\u2010Darm\u2010Kanals des Menschen","volume":"6","author":"Schulze J.","year":"1982","journal-title":"Mikrobielle Umwelt und antimikrobielle Ma\u00dfnahmen"},{"key":"e_1_2_1_7_2","first-page":"48","volume-title":"Advances in germfree research and gnotobiology","author":"Miyakawa M.","year":"1968"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)86598-X"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1159\/000176721"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/0003-2697(68)90263-7"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1099\/00222615-9-3-335"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9861(66)90238-4"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/food.19670110742"},{"key":"e_1_2_1_14_2","first-page":"96","volume":"52","author":"Poiffait A.","year":"1982","journal-title":"Intern. Z. Vitamin\u2010 u. Ern\u00e4hr.\u2010Forsch."},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/food.19790230415"}],"container-title":["Food \/ Nahrung"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Ffood.19840280429","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/food.19840280429","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,19]],"date-time":"2023-10-19T21:06:14Z","timestamp":1697749574000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/food.19840280429"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1984,1]]},"references-count":14,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1984,1]]}},"alternative-id":["10.1002\/food.19840280429"],"URL":"https:\/\/doi.org\/10.1002\/food.19840280429","archive":["Portico"],"relation":{},"ISSN":["0027-769X","1521-3803"],"issn-type":[{"value":"0027-769X","type":"print"},{"value":"1521-3803","type":"electronic"}],"subject":[],"published":{"date-parts":[[1984,1]]}}}