{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,2]],"date-time":"2023-09-02T05:08:23Z","timestamp":1693631303640},"reference-count":7,"publisher":"Wiley","issue":"5-6","license":[{"start":{"date-parts":[[2006,10,19]],"date-time":"2006-10-19T00:00:00Z","timestamp":1161216000000},"content-version":"vor","delay-in-days":7231,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nahrung"],"published-print":{"date-parts":[[1987,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Beim Morbus Whipple handelt es sich um eine bakteriell verursachte Systemerkrankung, bei der es zur Bildung von Mucopolysacchariden kommt, die Makrophagen aufnehmen. Bei einem 60j\u00e4hrigen Patienten mit dieser Erkrankung konnten wir im Schleimhautbioptat elektronenmikroskopisch massenhaft St\u00e4bchen\u2010bakterien nachweisen, die kulturell <jats:italic>Propionibacterium<\/jats:italic> zugeordnet werden konnten. Im Duodenalsaft lie\u00dfen sich neben Aerobiern auch Striktanaerobier finden. Die Therapie mit Tetracyclin erbrachte eine rasche und eindeutige Besserung der klinischen Zeichen der Resorptionsst\u00f6rung, weniger aber der histologischen Befunde.<\/jats:p>","DOI":"10.1002\/food.19870310567","type":"journal-article","created":{"date-parts":[[2006,11,3]],"date-time":"2006-11-03T00:16:25Z","timestamp":1162512985000},"page":"553-555","source":"Crossref","is-referenced-by-count":0,"title":["Morbus Whipple, ein Beispiel f\u00fcr Wechselwirkungen zwischen Gastrointestinalflora und Makroorganismus?"],"prefix":"10.1002","volume":"31","author":[{"given":"M.","family":"Knoke","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"M\u00f6llmann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Bernhardt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Lorenz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"K\u00f6nigstedt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,10,19]]},"reference":[{"key":"e_1_2_1_2_2","volume-title":"Farbatlas der Endoskopie und Bopsie des Darmes","author":"Beck K.","year":"1973"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.3.5983.568"},{"key":"e_1_2_1_4_2","first-page":"107","volume":"78","author":"Comer G. M.","year":"1983","journal-title":"Am. J. Gastroenterol."},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01391638"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(78)90421-3"},{"key":"e_1_2_1_7_2","first-page":"168","volume":"4","author":"Roschlau G.","year":"1978","journal-title":"Med. akt."},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1159\/000198017"}],"container-title":["Food \/ Nahrung"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Ffood.19870310567","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/food.19870310567","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T22:00:16Z","timestamp":1693605616000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/food.19870310567"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1987,1]]},"references-count":7,"journal-issue":{"issue":"5-6","published-print":{"date-parts":[[1987,1]]}},"alternative-id":["10.1002\/food.19870310567"],"URL":"https:\/\/doi.org\/10.1002\/food.19870310567","archive":["Portico"],"relation":{},"ISSN":["0027-769X","1521-3803"],"issn-type":[{"value":"0027-769X","type":"print"},{"value":"1521-3803","type":"electronic"}],"subject":[],"published":{"date-parts":[[1987,1]]}}}