{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T02:00:12Z","timestamp":1780365612987,"version":"3.54.1"},"reference-count":34,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2020,3,18]],"date-time":"2020-03-18T00:00:00Z","timestamp":1584489600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"National Science Foundation for Youths of China","award":["31401606"],"award-info":[{"award-number":["31401606"]}]},{"name":"The Innovation Project of Medicinal Plant Germplasm Resources and Breeding Innovation Team"},{"name":"The Chinese Academy of Agricultural Sciences","award":["CAAS-ASTIP-2016-ISAPS"],"award-info":[{"award-number":["CAAS-ASTIP-2016-ISAPS"]}]},{"name":"The Project of the Jilin Province Department of Science and Technology, China","award":["20190201160JC"],"award-info":[{"award-number":["20190201160JC"]}]},{"name":"The Project of the Jilin Province Department of Science and Technology, China","award":["20170101011JC"],"award-info":[{"award-number":["20170101011JC"]}]},{"name":"The Project of the Jilin Province Department of Science and Technology, China","award":["20170203004YY"],"award-info":[{"award-number":["20170203004YY"]}]},{"DOI":"10.13039\/100015800","name":"Jilin Province Development and Reform Commission","doi-asserted-by":"crossref","award":["2019C052-10"],"award-info":[{"award-number":["2019C052-10"]}],"id":[{"id":"10.13039\/100015800","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Food Science &amp; Nutrition"],"published-print":{"date-parts":[[2020,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The study estimated changes of 5\u2010hydroxymethyl\u20102\u2010furfuraldehyde (5\u2010HMF) in different ginseng products with different temperatures and time pretreatment. Heat treatment was performed at various temperatures for 1.50, 2.00, 2.50, and 3.00\u00a0hr, respectively. Ultrasonic extraction and reflux extraction were used to evaluate the extraction rate and different solvents (such as 80% methanol, dichloromethane, ethyl acetate, and an extraction with both dichloromethane and ethyl acetate solvents) using two extraction methods (liquid\u2013liquid extraction and solid\u2010phase extraction) to remove matrix interference. An ultraperformance liquid chromatography\u2013mass spectrometer (UPLC\u2010MS) method was used for quantitative and changing analysis of 5\u2010HMF in different ginseng samples. The results indicated that the content of 5\u2010HMF increased dramatically with heating temperature and time, and the 5\u2010HMF in the ginseng samples ranged from 0.01 to 112.32\u00a0g\/kg protein. The highest value was observed in the honey\u2010added ginseng samples with the highest amount of addition and highest temperature treatment, and the lowest value was found in the fresh ginseng samples. These results implied that 5\u2010HMF may be as an indicator to estimate the honey addition level and heat treatment degree during the processing of ginseng products, and the content of 5\u2010HMF is a promising parameter to evaluate the quality of products (ginseng). The production and regulation of potentially harmful Maillard reaction products (PHMRPs)\u20105\u2010HMF in ginseng manufacture will provide an important reference for safe ginseng processing.<\/jats:p>","DOI":"10.1002\/fsn3.1496","type":"journal-article","created":{"date-parts":[[2020,3,18]],"date-time":"2020-03-18T21:17:44Z","timestamp":1584566264000},"page":"2068-2075","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Changes of 5\u2010hydroxymethyl\u20102\u2010furfural in fresh and processed ginsengs"],"prefix":"10.1002","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7401-6975","authenticated-orcid":false,"given":"Yali","family":"Li","sequence":"first","affiliation":[{"name":"Institute of Special Wild Economic Animals and Plants Chinese Academy of Agriculture Sciences Changchun Jilin 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