{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,30]],"date-time":"2025-12-30T23:28:01Z","timestamp":1767137281898,"version":"build-2238731810"},"reference-count":19,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2020,6,15]],"date-time":"2020-06-15T00:00:00Z","timestamp":1592179200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004119","name":"Liaoning Medical University","doi-asserted-by":"publisher","award":["XZJJ20140234"],"award-info":[{"award-number":["XZJJ20140234"]}],"id":[{"id":"10.13039\/501100004119","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005047","name":"Natural Science Foundation of Liaoning Province","doi-asserted-by":"publisher","award":["20170540365"],"award-info":[{"award-number":["20170540365"]}],"id":[{"id":"10.13039\/501100005047","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Food Science &amp; Nutrition"],"published-print":{"date-parts":[[2020,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Previous epidemiological and histopathological studies have demonstrated that long\u2010term computation of Kweichow Moutai liquor (Moutai) could induce fatty liver disease but few of these patients with fatty liver will develop hepatic fibrosis or cirrhosis. Moutai liquor has a different brewing technique from other white wine, which may generate various microorganisms in the unique geographical conditions and may produce plenty of vitamins, amino acids, and several essential microelements. In the current study, we evaluated the potential protective effect of Moutai liquor in alcohol\u2010induced liver fibrosis mouse model. Both in vivo and in vitro studies were performed for exploring the possible mechanisms in suppressing liver fibrosis by Moutai. We demonstrated that Moutai treatment induced hepatic stellate cell (HSC) apoptosis and suppressed collagen deposition, as well as attenuated hepatic fibrosis. The antifibrosis mechanism of Moutai was possibly related with the inhibition of Kupffer cell and HSC activation via suppressing NF\u03baB nuclear translocation and preventing the expression of pro\u2010inflammatory cytokines. It is worth noting that although Moutai attenuates liver fibrosis, it still causes lipid metabolic abnormalities in mouse liver and induces fatty liver. Kweichow Moutai may ameliorate alcohol\u2010induced liver fibrosis in mice by targeting the NF\u03baB pathway.<\/jats:p>","DOI":"10.1002\/fsn3.1716","type":"journal-article","created":{"date-parts":[[2020,6,16]],"date-time":"2020-06-16T01:29:23Z","timestamp":1592270963000},"page":"4214-4222","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["<i>Retracted:<\/i>\n                    Kweichow Moutai ameliorates alcohol\u2010induced liver fibrosis in mice by targeting the NF\u03baB pathway"],"prefix":"10.1002","volume":"8","author":[{"given":"Tao","family":"Yang","sequence":"first","affiliation":[{"name":"Department of General Surgery The First Affiliated Hospital of Jinzhou Medical University Jinzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu","family":"Feng","sequence":"additional","affiliation":[{"name":"Department of Traumatology General Hospital of Ningxia Medical University Yinchuan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yifan","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of General Surgery The First Affiliated Hospital of Jinzhou Medical University Jinzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of General Surgery The First Affiliated Hospital of Jinzhou Medical University Jinzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shutian","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of General Surgery The First Affiliated Hospital of Jinzhou Medical University Jinzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sijin","family":"Yang","sequence":"additional","affiliation":[{"name":"Southwestern Medical University Affiliated Chinese Medicine Hospital Luzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3989-8543","authenticated-orcid":false,"given":"Ming","family":"Hong","sequence":"additional","affiliation":[{"name":"Science and Technology Innovation Center Guangzhou University of Chinese Medicine Guangzhou China"},{"name":"Institute of Clinical Pharmacology Guangzhou University of Chinese Medicine Guangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,6,15]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/fsn3.139"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v8.i3.520"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/mnfr.201400649"},{"key":"e_1_2_9_5_1","first-page":"93","article-title":"Effect of Maotai liquor on the liver: An experimental study","volume":"3","author":"Cheng M. 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