{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T11:03:15Z","timestamp":1788519795108,"version":"build-2803163510"},"reference-count":29,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,11,10]],"date-time":"2020-11-10T00:00:00Z","timestamp":1604966400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100005317","name":"Kermanshah University of Medical Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005317","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Food Science &amp; Nutrition"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Vitamin D deficiency can be regarded as one of the overgrowing health problem in all of the world. Evidence from a clinical trial suggested a role for probiotic bacteria in increasing vitamin D. However, probiotic's effect is strain specific and this effect should be confirmed about different strains. The objective was to determine if yogurt fortification with probiotic bacteria,\n                    <jats:italic>Lactobillus acidophilus<\/jats:italic>\n                    La\u2010B5,\n                    <jats:italic>Bifidobacterium lactis<\/jats:italic>\n                    Bb\u201012 either alone or in combination with vitamin D can be a complementary treatment for vitamin D deficiency\n                    <jats:sub>.<\/jats:sub>\n                    The end\u2010points were vitamin D, cardio metabolic lipid profile, anthropometric indices (weight, height, waist, hip, fat mass, lean body mass) and dietary intake. A 10\u2010week parallel\u2010group, double\u2010blind, randomized and controlled trial was conducted on 140 obese men and women. The participants were randomly allocated to receive 100 grams either 1) plain low\u2010fat yogurt or 2) probiotic yogurt or 3) vitamin D\u2010fortified yogurt or 4) probiotic and vitamin D cofortified yogurt. All groups received low\u2010calorie diet. Vitamin D increased significantly in group 4 (\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0=\u00a0.008), group 3 (\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0=\u00a0.001) and group 1 (\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0=\u00a0.012 with no difference between groups. Vitamin D\u2010fortified yogurt had the most effect size and showed a significant difference versus plain (\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0=\u00a0.018) and probiotic yogurt (\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0=\u00a0.002). Regarding lipid profile, there were no significant differences between groups. Data from this study does not support the hypothesis that yogurt fortified with probiotic bacteria,\n                    <jats:italic>Lactobillus acidophilus<\/jats:italic>\n                    La\u20105 and\n                    <jats:italic>Bifidobacterium lactis<\/jats:italic>\n                    Bb\u201012 either alone or in combination with vitamin D might impose any increasing effect on serum level of vitamin D in comparison with vitamin D\u2010fortified yogurt.\n                  <\/jats:p>","DOI":"10.1002\/fsn3.1996","type":"journal-article","created":{"date-parts":[[2020,11,10]],"date-time":"2020-11-10T05:41:15Z","timestamp":1604986875000},"page":"303-312","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["The effect of yogurt co\u2010fortified with probiotic and vitamin D on lipid profile, anthropometric indices and serum 25\u2010hydroxi vitamin D in obese adult: A Double\u2010Blind Randomized\u2010 Controlled Trial"],"prefix":"10.1002","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9927-5116","authenticated-orcid":false,"given":"Shima","family":"Hajipoor","sequence":"first","affiliation":[{"name":"Nutritional Sciences Department School of Nutritional Sciences and Food Technology Kermanshah University of Medical Sciences Kermanshah Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1944-0052","authenticated-orcid":false,"given":"Azita","family":"Hekmatdoost","sequence":"additional","affiliation":[{"name":"Department of Clinical Nutrition School of Nutrition Sciences &amp; Food Technology Shahid Beheshti University of Medical Sciences Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6446-7289","authenticated-orcid":false,"given":"Mansour","family":"Rezaei","sequence":"additional","affiliation":[{"name":"Department of Biostatistics School of Health, Social Development and Health Promotion Research Center Research Institute for Health, Kermanshah University of Medical Science Kermanshah Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7265-3495","authenticated-orcid":false,"given":"Seyed Mostafa","family":"Nachvak","sequence":"additional","affiliation":[{"name":"Nutritional Sciences Department School of Nutritional Sciences and Food Technology Kermanshah University of Medical Sciences Kermanshah Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3722-0528","authenticated-orcid":false,"given":"Meysam","family":"Alipour","sequence":"additional","affiliation":[{"name":"Alimentary Tract Research Center, Ahvaz Jundishapur University of Medical Sciences Ahvaz Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6070-0146","authenticated-orcid":false,"given":"Sodabeh","family":"Eskandari","sequence":"additional","affiliation":[{"name":"Department of Biostatistics School of Health, Social Development and Health Promotion Research Center Research Institute for Health, Kermanshah University of Medical Science Kermanshah Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1383-9409","authenticated-orcid":false,"given":"Roghayeh","family":"Mostafai","sequence":"additional","affiliation":[{"name":"Nutritional Sciences Department School of Nutritional Sciences and Food Technology Kermanshah University of Medical Sciences Kermanshah Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7333-1316","authenticated-orcid":false,"given":"Mohammad Reza","family":"Sobhiyeh","sequence":"additional","affiliation":[{"name":"Vascular and Endovascular Surgeon, Department of Surgery, Imam Reza Hospital Kermanshah University of Medical Sciences Kermanshah Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5572-6114","authenticated-orcid":false,"given":"Reza","family":"Mohammadi","sequence":"additional","affiliation":[{"name":"Department of Food Science and Technology School of Nutrition Sciences and Food Technology Kermanshah University of Medical Sciences Kermanshah Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3898-9139","authenticated-orcid":false,"given":"Yahya","family":"Pasdar","sequence":"additional","affiliation":[{"name":"Nutritional Sciences Department School of Nutritional Sciences and Food Technology Kermanshah University of Medical Sciences Kermanshah Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,11,10]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11154\u2010017\u20109410\u20107"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/clinchem\/18.6.499"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.numecd.2014.07.012"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2012\u20104262"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2796.2009.02181.x"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/ejcn.2010.19"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.7860\/JCDR\/2014\/8519.4611"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.7570\/jomes.2019.28.4.278"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.00398.2007"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.14715\/cmb\/2015.61.3.8"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2011.02.015"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.115.120170.1"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jnutbio.2014.05.010"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.113.073734"},{"issue":"3","key":"e_1_2_10_16_1","first-page":"123","article-title":"Probiotic supplements and food products: Comparison for different targets","volume":"4","author":"Mollakhalili M. N.","year":"2017","journal-title":"Applied Food Biotechnology"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.117.152736"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/obr.12239"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0029665114001578"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjsm.2010.078972.60"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13594\u2010014\u20100189\u2010y"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1186\/1475\u20102891\u201011\u201078"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2012.10.021"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jadohealth.2015.02.006"},{"issue":"1","key":"e_1_2_10_25_1","first-page":"27","article-title":"Large individual differences in serum 25\u2010Hydroxyvitamin D response to vitamin D supplementation: Effects of genetic factors, body mass index, and baseline concentration. results from a randomized controlled trial","volume":"48","author":"Sollid S.","year":"2016","journal-title":"Hormone and Metabolic Research"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13679\u2010020\u201000379\u2010w"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1097\/MED.0000000000000371"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13679\u2010015\u20100176\u20105"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000009679"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1155\/2011\/971938"}],"container-title":["Food Science &amp; Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/fsn3.1996","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/fsn3.1996","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/fsn3.1996","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,3]],"date-time":"2024-05-03T01:22:48Z","timestamp":1714699368000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/fsn3.1996"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11,10]]},"references-count":29,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,1]]}},"alternative-id":["10.1002\/fsn3.1996"],"URL":"https:\/\/doi.org\/10.1002\/fsn3.1996","archive":["Portico"],"relation":{},"ISSN":["2048-7177","2048-7177"],"issn-type":[{"value":"2048-7177","type":"print"},{"value":"2048-7177","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,11,10]]},"assertion":[{"value":"2020-07-29","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-10-20","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-11-10","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}