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In our study, the effects of 12 tea extracts on NAFLD were assessed and compared at the dose of 200\u00a0mg\/kg body weight in mice fed with a high\u2010fat diet (HFD) for 15\u00a0weeks. Enshi Yulu Tea, Fenghuang Narcissus Tea, and Yihong Tea showed strong effects in suppressing the accumulation of epididymal and perirenal adipose tissue as well as the increases of body weight and liver weight. The histopathological analysis revealed that hepatic steatosis and adipocyte hypertrophy induced by a HFD could be ameliorated by tea supplementation. In addition, Enshi Yulu Tea and Qing Brick Tea exerted more remarkable functions on decreasing the level of serum triglyceride and preventing hepatic fat accumulation, respectively. Furthermore, Fenghuang Narcissus Tea, Enshi Yulu Tea, and Qing Brick Tea could reverse the abnormal change in the levels of glutathione and superoxide dismutase. Moreover, 13 phytoconstituents were detected and quantified in these teas with high\u2010performance liquid chromatography (HPLC) method. The correlation analysis demonstrated that gallic acid might decrease MDA level, and the reduction of liver weight might be attributed to ellagic acid. However, it should be paid attention to some teas that showed hepatotoxicity with elevated levels of aspartate transaminase and alanine aminotransferase. Several teas showed strong effects in the prevention of NAFLD, which could be developed into functional foods against NAFLD.<\/jats:p>","DOI":"10.1002\/fsn3.2255","type":"journal-article","created":{"date-parts":[[2021,4,9]],"date-time":"2021-04-09T11:02:11Z","timestamp":1617966131000},"page":"2954-2967","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Effects of several tea extracts on nonalcoholic fatty liver disease in mice fed with a high\u2010fat diet"],"prefix":"10.1002","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3332-2922","authenticated-orcid":false,"given":"Qian\u2010Qian","family":"Mao","sequence":"first","affiliation":[{"name":"Guangdong Provincial Key Laboratory of Food, Nutrition and Health Department of Nutrition School of Public Health Sun Yat\u2010Sen University Guangzhou 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