{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T17:36:07Z","timestamp":1790012167007,"version":"4.0.1"},"reference-count":43,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2021,5,3]],"date-time":"2021-05-03T00:00:00Z","timestamp":1620000000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Food Science &amp; Nutrition"],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Recent studies suggested that vitamin D is linked with obesity, but evidence in infants is scarce. Therefore, we aimed to make an exploration in infants. A total of 414 infants at one year old who visited Maternity and Child Health Care Hospital of Wuxi in China were recruited. Finger\u2010stick blood sampling was conducted in all the subjects, and serum 25\u2010hydroxyvitamin D [25(OH)D] concentrations were measured. Maternal characteristics during pregnancy and infantile information were collected by questionnaires or extracting from medical records. Multivariable linear models were performed to assess the relationship between 25(OH)D and body mass index (BMI), while multivariable logistic regression models were used to examine the association between 25(OH)D and obesity. Among the 414 infants, 69 (16.67%) and 81 (19.57%) infants were defined as obesity and vitamin D deficiency [25(OH)D\u00a0&lt;\u00a050\u00a0nmol\/L], respectively. The mean (<jats:italic>SD<\/jats:italic>) of 25(OH)D concentration was 68.05 (19.05) in infants without obesity, which was significantly higher than that of obese infants [60.36(18.49), <jats:italic>p<\/jats:italic>\u00a0=\u00a0.002]. Inverse linear relationships were observed between 25(OH)D level and BMI (<jats:italic>\u03b2<\/jats:italic>\u00a0=\u00a0\u22120.017, <jats:italic>p<\/jats:italic>\u00a0=\u00a0.004) as well as BMI <jats:italic>Z<\/jats:italic>\u2010score (<jats:italic>\u03b2<\/jats:italic>\u00a0=\u00a0\u22120.010, <jats:italic>p<\/jats:italic>\u00a0=\u00a0.004). Furthermore, vitamin D deficiency was associated with an increased risk of obesity of infants (adjusted odds ratio\u00a0=\u00a02.74, 95% confidence interval\u00a0=\u00a01.20\u20136.25, with 25(OH)D\u00a0\u2265\u00a075\u00a0nmol\/L as a reference). The results showed that serum 25(OH)D concentrations were significantly lower in infants with obesity, suggesting vitamin D deficiency may be an independent risk factor for obesity among one\u2010year\u2010old Chinese infants.<\/jats:p>","DOI":"10.1002\/fsn3.2279","type":"journal-article","created":{"date-parts":[[2021,5,3]],"date-time":"2021-05-03T13:28:57Z","timestamp":1620048537000},"page":"3191-3199","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Association between serum 25\u2010hydroxyvitamin D concentrations and obesity in one\u2010year\u2010old Chinese infants"],"prefix":"10.1002","volume":"9","author":[{"given":"Bingbing","family":"Guo","sequence":"first","affiliation":[{"name":"Department of Child Health Care The Affiliated Wuxi Maternity and Child Health Care Hospital of Nanjing Medical University  Wuxi, Jiangsu 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Epidemiology and Biostatics Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases School of Public Health Medical College of Soochow University  Suzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingtong","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatics Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases School of Public Health Medical College of Soochow University  Suzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingjing","family":"Pei","sequence":"additional","affiliation":[{"name":"Department of Child Health Care The Affiliated Wuxi Maternity and Child Health Care Hospital of Nanjing Medical University  Wuxi, Jiangsu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ran","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Child Health Care The Affiliated 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