{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T01:55:31Z","timestamp":1786326931379,"version":"build-2736575974"},"reference-count":47,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2021,9,9]],"date-time":"2021-09-09T00:00:00Z","timestamp":1631145600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31972031"],"award-info":[{"award-number":["31972031"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Food Science &amp; Nutrition"],"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The yields, properties, and bioactivities of polysaccharides extracted by three methods from soybean hulls (SSCPs) were evaluated: hot water extraction (H\u2010SSCP), microwave\u2010assisted ammonium oxalate extraction (A\u2010SSCP), and microwave\u2010assisted sodium citrate extraction (S\u2010SSCP). A\u2010SSCP gave the highest yield of polysaccharides (9.3\u00a0\u00b1\u00a00.5%) although all three products had similar physicochemical characteristics and FT\u2010IR spectra. A\u2010SSCP and S\u2010SSCP produced polysaccharides with lower molecular weight distributions and higher total reducing power and scavenging ability for ABTS<jats:sup>+<\/jats:sup>\u2022 and DPPH\u2022 free radicals. Furthermore, the effect of SSCPs on carbon tetrachloride (CCl<jats:sub>4<\/jats:sub>)\u2010induced liver injury was investigated in the mice. When compared with H\u2010SSCP and S\u2010SSCP, A\u2010SSCP significantly decreased the levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), malondialdehyde (MDA), and reactive oxygen (ROS) to normal (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.05) and increased the level of glutathione (GSH) to normal (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.05). A\u2010SSCP was the most effective polysaccharide, yielding an approximately normal hepatic appearance with well\u2010preserved cytoplasm, obvious cell boundaries, with legible nuclei and nucleoli. This study indicates that polysaccharides extracted from soybean hulls via microwave\u2010assisted ammonium oxalate extraction have the potential to be developed as a new functional food contributing to the alleviation of liver damage.<\/jats:p>","DOI":"10.1002\/fsn3.2483","type":"journal-article","created":{"date-parts":[[2021,9,9]],"date-time":"2021-09-09T11:46:51Z","timestamp":1631188011000},"page":"5928-5938","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":29,"title":["Effect of extraction method on the chemical profiles and bioactivities of soybean hull polysaccharides"],"prefix":"10.1002","volume":"9","author":[{"given":"Lin","family":"Han","sequence":"first","affiliation":[{"name":"College of Food Science and Technology Bohai University Jinzhou 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