{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T20:14:46Z","timestamp":1790799286748,"version":"4.1.0"},"reference-count":128,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2021,8,15]],"date-time":"2021-08-15T00:00:00Z","timestamp":1628985600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Food Science &amp; Nutrition"],"published-print":{"date-parts":[[2021,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Infertility is defined as the failure to achieve a successful pregnancy after 12\u00a0months\u2019 sexual activity that affects 15%\u201317% of couples in the world and about 50% of them are related to female infertility factors. In this study, using the PRISMA checklist and MeSH keywords, 128 articles were extracted from various databases (PubMed, Cochrane library, WHO, Iranmedex, Science Direct, SID, and Google Scholar search engine) without language and time restrictions, and 128 articles were selected after eliminating duplicate studies. In this review, we present some solid evidence for role of herbal medicine in the treatment of female infertility. The results of this study showed that different parts of some plants are rich in polyphenolic compounds (isoflavones and flavonoids) and other compounds which are beneficial to in reproductive health in women. The compounds in these plants, along with regulating the female endocrine pathways, and improving symptoms of menopause, treat female reproductive disorders such as polycystic ovary syndrome (PCOS), premature ovarian failure (POF), endometriosis, hyperprolactinemia, and hypothalamic dysfunction; moreover, because of their anticancer, antioxidant, and antidepressant properties, they can be used in traditional medicine or in the pharmaceutical industry as safe compounds in women's health.<\/jats:p>","DOI":"10.1002\/fsn3.2523","type":"journal-article","created":{"date-parts":[[2021,8,16]],"date-time":"2021-08-16T02:37:05Z","timestamp":1629081425000},"page":"5869-5882","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":92,"title":["Female infertility and herbal medicine: An overview of the new findings"],"prefix":"10.1002","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9162-8706","authenticated-orcid":false,"given":"Mohsen","family":"Akbaribazm","sequence":"first","affiliation":[{"name":"Fertility and Infertility Research Center Health Technology Institute Kermanshah University of Medical Sciences Kermanshah Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4704-6076","authenticated-orcid":false,"given":"Nader","family":"Goodarzi","sequence":"additional","affiliation":[{"name":"Department of Basic Sciences and Pathobiology Faculty of Veterinary Medicine Razi University Kermanshah Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2537-651X","authenticated-orcid":false,"given":"Mohsen","family":"Rahimi","sequence":"additional","affiliation":[{"name":"Department of Parasitology and Mycology School of Medicine Student Research Committee Shahid Beheshti University of Medical Sciences Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,8,15]]},"reference":[{"issue":"11","key":"e_1_2_11_2_1","first-page":"18","article-title":"A review on herbal medicines effective of premenstrual syndrome in Iran","volume":"19","author":"Abdnejad R.","year":"2016","journal-title":"The Iranian Journal of Obstetrics, Gynecology and Infertility"},{"issue":"14","key":"e_1_2_11_3_1","first-page":"1","article-title":"Comparison of the Effect of chamomile matricaria and mefenamic acid capsules on postpartum hemorrhage in women with postpartum pain","volume":"19","author":"Abedian Z.","year":"2016","journal-title":"The Iranian Journal of Obstetrics, Gynecology and Infertility"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2013.09.008"},{"issue":"5","key":"e_1_2_11_5_1","first-page":"1175","article-title":"Physicochemical and phytochemical standardization with HPTLC fingerprinting of Nigella sativa L. seeds","volume":"27","author":"Ahmad A.","year":"2014","journal-title":"Pakistan Journal of Pharmaceutical Sciences"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/and.13294"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12565\u2010016\u20100332\u20103"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.4103\/2221-1691.298628"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/fsn3.1820"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chmed.2020.02.002"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/fsn3.1724"},{"issue":"1","key":"e_1_2_11_12_1","first-page":"20","article-title":"Medicinal uses of chemical extracts from Withania somnifera and its antimicrobial activity: A mini\u2010review","volume":"2","author":"Ali K.","year":"2017","journal-title":"PSM Microbiology"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.repbio.2015.12.001"},{"issue":"7","key":"e_1_2_11_14_1","first-page":"573","article-title":"Mammary gland stimulating effects of the crude phenolic extracts of green tea (Camellia sinensis)","volume":"6","author":"Al\u2010Snafi A. 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