{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T22:35:14Z","timestamp":1785537314908,"version":"3.56.0"},"reference-count":37,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2021,8,25]],"date-time":"2021-08-25T00:00:00Z","timestamp":1629849600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Food Science &amp; Nutrition"],"published-print":{"date-parts":[[2021,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    We examined dietary intake of creatine in U.S. men and women aged 65\u00a0years and over, and evaluated the association between creatine intake and risk of self\u2010reported medical conditions, and physical functioning\/disability variables using data from the 2017\u20132018 National Health and Nutrition Examination Survey (NHANES). The NHANES 2017\u20132018 target population included the noninstitutionalized civilian resident population of the United States aged 65\u00a0years and over. Detailed dietary intake data from NHANES elderly were obtained by dietary interview component through a 24\u2010h dietary recall interview, with estimated individual values for total grams of creatine consumed per day for each respondent. A threshold for dietary intake of creatine used to calculate risk between creatine intake and medical conditions was set at 1.00\u00a0g\/day. The sample population included 1500 participants aged 65\u00a0years and older, of which 1221 individuals (627 men and 594 women) provided detailed dietary data via a dietary interview. Creatine intake across all participants was 0.76\u00a0\u00b1\u00a00.79\u00a0g\/day (95% CI from 0.72 to 0.81). As much as 70% of U.S. elderly consume &lt;1.00\u00a0g of creatine per day, with about 1 in 5 individuals (19.8%) consume no creatine at all. Elderly with the suboptimal intake of creatine were found to have 2.62 times higher risk of angina pectoris (adjusted OR\u00a0=\u00a02.62, 95% CI from 1.14 to 6.01,\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0=\u00a0.023) and 2.59 times higher risk of liver conditions (adjusted OR\u00a0=\u00a02.59, 95% CI from 1.23 to 5.48,\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0=\u00a0.013), compared with older counterparts who consume \u22651.00\u00a0g of creatine per day after controlling for demographic and nutritional variables. The considerable shortage of dietary creatine is associated with an increased risk of heart and liver conditions, which calls for public measures that foster diets rich in creatine\u2010containing foods, and additional research to investigate the role of creatine in age\u2010related diseases.\n                  <\/jats:p>","DOI":"10.1002\/fsn3.2543","type":"journal-article","created":{"date-parts":[[2021,8,26]],"date-time":"2021-08-26T00:46:46Z","timestamp":1629938806000},"page":"5746-5754","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Dietary intake of creatine and risk of medical conditions in U.S. older men and women: Data from the 2017\u20132018 National Health and Nutrition Examination Survey"],"prefix":"10.1002","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7270-2541","authenticated-orcid":false,"given":"Sergej M.","family":"Ostojic","sequence":"first","affiliation":[{"name":"FSPE Applied Bioenergetics Lab University of Novi Sad Novi Sad Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darinka","family":"Korovljev","sequence":"additional","affiliation":[{"name":"FSPE Applied Bioenergetics Lab University of Novi Sad Novi Sad Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valdemar","family":"Stajer","sequence":"additional","affiliation":[{"name":"FSPE Applied Bioenergetics Lab University of Novi Sad Novi Sad Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,8,25]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.3945\/an.115.009258"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12970\u2010021\u201000412\u2010w"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41398\u2010020\u20100741\u2010x"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/med.21590"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.2174\/1389557515666150722102613"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamda.2013.05.021"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1017\/S000711451800017X"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00726\u2010011\u20100853\u2010y"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00726\u2010016\u20102188\u20101"},{"key":"e_1_2_10_11_1","volume-title":"NHANES 2017\u20102018 questionnaire instruments","author":"CDC\/National Center for Health Statistics","year":"2020"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12603\u2010018\u20101148\u20108"},{"issue":"184","key":"e_1_2_10_13_1","first-page":"1","article-title":"National Health and Nutrition Examination Survey, 2015\u22122018: Sample design and estimation procedures. 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