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The fact that egg is rich in choline suggests that excessive egg consumption may increase TMAO production by altering the gut microbiota. However, the effects of egg consumption on vascular function and gut microbiota remain unclear. Here, the diet of nine young male subjects was supplemented with two boiled eggs daily for 2\u00a0weeks. Changes in vascular function, inflammation, metabolism, oxidative stress, and gut microbiota were examined. We found that egg consumption increased flow\u2010mediated dilation and decreased brachial\u2010ankle pulse wave velocity. Furthermore, egg consumption positively modulated the gut microbiota function but had no effects on the levels of C\u2010reactive protein, glucose, lipid profile, malondialdehyde, superoxide dismutase, or TMAO. The current study provides evidence that egg consumption improves vascular function, which may be related to the alterations seen in the gut microbiota. Therefore, moderate egg consumption may help to improve vascular and intestinal function in individuals at low risk of developing CVD and other metabolic disorders.<\/jats:p>","DOI":"10.1002\/fsn3.2671","type":"journal-article","created":{"date-parts":[[2021,11,30]],"date-time":"2021-11-30T16:54:34Z","timestamp":1638291274000},"page":"295-304","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Egg consumption improves vascular and gut microbiota function without increasing inflammatory, metabolic, and oxidative stress markers"],"prefix":"10.1002","volume":"10","author":[{"given":"Xiang","family":"Liu","sequence":"first","affiliation":[{"name":"Department of Cardiac Surgery Guangdong Cardiovascular Institute Guangdong Provincial People\u2019s Hospital Guangdong Academy of Medical Sciences Guangzhou China"},{"name":"Guangdong Provincial Key Laboratory of South China Structural Heart Disease Guangzhou 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