{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T22:13:07Z","timestamp":1791238387337,"version":"4.1.0"},"reference-count":24,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2022,11,8]],"date-time":"2022-11-08T00:00:00Z","timestamp":1667865600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Food Science &amp; Nutrition"],"published-print":{"date-parts":[[2023,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Iron deficiency anemia is the most common type of micronutrient deficiency in the world. Adolescence represents a period of increased risk of iron deficiency. Therefore, we aimed to determine the impact of nutrition education by a digital game on markers of iron\u2010deficient anemia in adolescent girls. In this study, 176 adolescent girls were randomly dichotomized into the intervention and control groups. At the beginning and the end of the intervention, knowledge, attitude, and practice of both groups were assessed by a questionnaire. Girls in the intervention group received the necessary education through a digital game during a 14\u2010week period, while those in the control group received basic nutritional education through PowerPoint and pamphlets. Additionally, serum transferrin, serum iron, transferrin saturation, ferritin, CBC difference, and total iron binding capacity (TIBC) tests were checked. In this study, nutrition education significantly increased the level of knowledge, attitude, and practice of adolescent girls regarding their diet (<jats:italic>p<\/jats:italic>\u00a0\u02c2\u00a0.05). Hemoglobin level was also significantly raised (<jats:italic>p<\/jats:italic>\u00a0\u02c2\u00a0.05). However, no significant effect was observed on other markers of iron\u2010deficient anemia, such as serum iron, TIBC, and hematocrit, in the intervention group compared with the control group (<jats:italic>p<\/jats:italic>\u00a0\u02c3\u00a0.05). The results of this study indicated the positive impact of nutrition education based on digital game on knowledge, attitude, and practice scores, as well as a significant difference in hemoglobin. It is recommended that educational games be designed for students in the future to promote health and nutrition information.<\/jats:p>","DOI":"10.1002\/fsn3.3120","type":"journal-article","created":{"date-parts":[[2022,11,8]],"date-time":"2022-11-08T17:49:18Z","timestamp":1667929758000},"page":"863-871","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Evaluating the effect of digital game\u2010based nutrition education on anemia indicators in adolescent girls: A randomized clinical trial"],"prefix":"10.1002","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1110-4249","authenticated-orcid":false,"given":"Omid Sabet","family":"Ghadam","sequence":"first","affiliation":[{"name":"Department of Community Nutrition, School of Nutrition and Food Sciences Shiraz University of Medical Sciences  Shiraz Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4572-3942","authenticated-orcid":false,"given":"Zahra","family":"Sohrabi","sequence":"additional","affiliation":[{"name":"Nutrition Research Center, School of Nutrition and Food Sciences Shiraz University of Medical Sciences  Shiraz Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2024-9415","authenticated-orcid":false,"given":"Manoosh","family":"Mehrabi","sequence":"additional","affiliation":[{"name":"Department of E\u2010learning in Medical Sciences, Virtual School, Center of Excellence for E\u2010leraning for Medical Sciences Shiraz University of Medical Sciences  Shiraz Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9362-328X","authenticated-orcid":false,"given":"Mohammad","family":"Fararouei","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, School of Health Shiraz University of Medical Sciences  Shiraz Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4345-9124","authenticated-orcid":false,"given":"Mansour","family":"Shahraki","sequence":"additional","affiliation":[{"name":"Department of Nutrition and Food Technology, Medical Faculty Zahedan University of Medical Sciences  Zahedan Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2664-6208","authenticated-orcid":false,"given":"Najme","family":"Hejazi","sequence":"additional","affiliation":[{"name":"Nutrition Research Center, School of Nutrition and Food Sciences Shiraz University of Medical Sciences  Shiraz Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cain C. T.","family":"Clark","sequence":"additional","affiliation":[{"name":"Centre for Intelligent Healthcare Coventry University  Coventry UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2032-9690","authenticated-orcid":false,"given":"Sanaz","family":"Mehrabani","sequence":"additional","affiliation":[{"name":"Department of clinical Nutrition, School of Nutrition and Food Science Food Security Research Center, Isfahan University of Medical Sciences  Isfahan Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shirin","family":"Gerami","sequence":"additional","affiliation":[{"name":"Nutrition Research Center, School of Nutrition and Food Sciences Shiraz University of Medical Sciences  Shiraz Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7031-3542","authenticated-orcid":false,"given":"Mehran","family":"Nouri","sequence":"additional","affiliation":[{"name":"Department of Community Nutrition, School of Nutrition and Food Sciences Shiraz University of Medical Sciences  Shiraz Iran"},{"name":"Students' Research Committee Shiraz University of Medical Sciences  Shiraz Iran"},{"name":"Health Policy Research Center, Institute of Health Shiraz University of Medical Sciences  Shiraz Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,11,8]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.heliyon.2021.e06348"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1080\/03670240802293675"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1177\/156482650602700309"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/0272684X17749566"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1515\/IJAMH.2005.17.2.179"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0114059"},{"key":"e_1_2_8_8_1","first-page":"37","article-title":"Effect of nutritional education on iron\u2010deficiency anemia in high schools girls","volume":"12","author":"Falahi E.","year":"2010","journal-title":"Journal of Shahrekord University of Medical Sciences"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1155\/2011\/284050"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.29169\/1927-5951.2020.10.02.4"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ypmed.2014.01.005"},{"issue":"2","key":"e_1_2_8_12_1","first-page":"1","article-title":"Effect of healthy nutrition education on the body mass index (BMI) of health volunteers in Ilam Province","volume":"4","author":"Jorvand R.","year":"2016","journal-title":"Health Education and Health Promotion (HEHP)"},{"issue":"12","key":"e_1_2_8_13_1","first-page":"1131","article-title":"Effectiveness of nutrition education, iron supplementation or both on iron status in children","volume":"40","author":"Kapur D.","year":"2003","journal-title":"Indian Pediatrics"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1037\/a0019441"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12905-021-01394-2"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1024\/0300-9831.74.4.264"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199109053251004"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpediatrics.2012.41"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.29333\/ejgm\/7884"},{"issue":"4","key":"e_1_2_8_20_1","first-page":"137","article-title":"Second national integrated micronutrient survey in Iran: Study design and preliminary findings","volume":"21","author":"Pouraram H.","year":"2018","journal-title":"Archives of Iranian Medicine"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2214-109X(13)70001-9"},{"key":"e_1_2_8_22_1","first-page":"1","volume-title":"Iron deficiency anaemia: Assessment, prevention and control, a guide for programme managers","author":"Unu W. 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