{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T14:53:34Z","timestamp":1789052014522,"version":"build-2803163510"},"reference-count":34,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2022,11,17]],"date-time":"2022-11-17T00:00:00Z","timestamp":1668643200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Food Science &amp; Nutrition"],"published-print":{"date-parts":[[2023,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Evidence on the association of 25\u2010hydroxyvitamin D (25[OH]D) and obesity during the first 5\u2009years of life is limited in China. The objective of this study was to examine the associations between weight, weight for age <jats:italic>z<\/jats:italic> score (ZWAZ), weight for length\/height <jats:italic>z<\/jats:italic> score (ZWHZ), and body mass index for age <jats:italic>z<\/jats:italic> score (ZBMI) and 25(OH)D. This was a large population\u2010based cross\u2010sectional multicenter study in which the children aged 0\u20135\u2009years were recruited from 12 children's healthcare centers by a stratified cluster random\u2010sampling method in 10 cities of the Jiangsu province, China. The 25(OH)D concentration was determined by ELISA. A total of 5289 children were investigated. For 0\u201371\u2009months children with obesity and nonobesity, the prevalence of vitamin D deficiency was 36.0% and 29.8%, and the 25(OH)D level was 59.8 and 64.0\u00a0nmol\/L, respectively, and there were all significant difference. Compared with children with nonobesity, children with obesity had higher risk of vitamin D deficiency (OR [95% CI]: 1.33 [1.02, 1.72], <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.05), and had lower 25(OH)D level (\u03b2\u00a0=\u00a0\u22123.84, 95% CI\u00a0=\u00a0\u22127.58, \u22120.09, <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.05). The results for children aged 24\u201371\u2009months were similar to those for children aged 0\u201371\u2009months. However, no significant difference was observed in children aged 0\u201323\u2009months. Vitamin D deficiency was observed in children with greater adiposity during the first 5\u2009years of life. However, the results mainly came from those in the age group of 2 to 5\u2009years instead of the first 2\u2009years in their lives.<\/jats:p>","DOI":"10.1002\/fsn3.3145","type":"journal-article","created":{"date-parts":[[2022,11,17]],"date-time":"2022-11-17T11:35:48Z","timestamp":1668684948000},"page":"1084-1095","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Is vitamin D deficiency influenced by obesity during the first 5\u2009years of life? A cross\u2010sectional multicenter study"],"prefix":"10.1002","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2400-384X","authenticated-orcid":false,"given":"Yan","family":"Zhao","sequence":"first","affiliation":[{"name":"Department of Clinical Nutrition Jiangsu Province Hospital, The First Affiliated Hospital of Nanjing Medical University  Nanjing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui","family":"Qin","sequence":"additional","affiliation":[{"name":"Department of Child Health Care, Jiangsu Women and Children Health Hospital, Women and Child Branch Hospital of Jiangsu Province Hospital The First Affiliated Hospital of Nanjing Medical University  Nanjing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong","family":"Hong","sequence":"additional","affiliation":[{"name":"Department of Child Health Care Drum Tower Maternity and Child Health Care Institute  Nanjing 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