{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T02:10:55Z","timestamp":1788401455552,"version":"build-2803163510"},"reference-count":53,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2023,8,23]],"date-time":"2023-08-23T00:00:00Z","timestamp":1692748800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100012021","name":"Iran University of Medical Sciences","doi-asserted-by":"publisher","award":["95\u201004\u201027\u201029848"],"award-info":[{"award-number":["95\u201004\u201027\u201029848"]}],"id":[{"id":"10.13039\/100012021","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Food Science &amp; Nutrition"],"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Hesperidin, as an antioxidant and anti\u2010inflammatory agent, has beneficial effects on cardiovascular diseases. This study aimed to determine the effects of hesperidin supplementation on inflammation, oxidative stress, and lipid profile in depressed coronary artery bypass graft surgery (CABG) patients. Eighty patients after coronary artery bypass graft surgery participated in this clinical trial and were randomly divided into two groups. The intervention group received 200\u2009mg\/d pure hesperidin supplement and the second group received placebo for 12\u2009weeks. Both groups continued their usual diet. Serum concentrations of inflammatory and stress oxidative markers (hs\u2010CRP, P\u2010selectin, and ox\u2010LDL) were measured and compared at baseline and the end of the intervention. The changes in serum levels of triglyceride were significantly different between the two groups (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.05). HDL\u2010c significantly increased in groups but the differences between the two groups were not statistically significant (<jats:italic>p<\/jats:italic>\u2009&gt;\u2009.05). Hesperidin did not affect FBS, other lipid parameters, hs\u2010CRP, P\u2010selectin, and OX\u2010LDL (<jats:italic>p<\/jats:italic>\u2009&gt;\u2009.05). SBP and DBP differences were not statistically significant (<jats:italic>p<\/jats:italic>\u2009&gt;\u2009.05). After 12\u2009weeks of intervention, hesperidin reduced serum levels of triglyceride in depressed post\u2010CABG patients.<\/jats:p>","DOI":"10.1002\/fsn3.3639","type":"journal-article","created":{"date-parts":[[2023,8,23]],"date-time":"2023-08-23T07:26:21Z","timestamp":1692775581000},"page":"7145-7154","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Hesperidin reduces serum levels of triglyceride after coronary artery bypass graft surgery"],"prefix":"10.1002","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6897-650X","authenticated-orcid":false,"given":"Zahra","family":"Booyani","sequence":"first","affiliation":[{"name":"Department of Nutrition, School of Public Health Iran University of Medical Sciences  Tehran 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